eb 1

EB1 is a potent and selective MNK kinase inhibitor with inhibitory effects on MNK1 and MNK2 with IC50 values of 0.69 μM and 9.4 μM, respectively.EB1 inhibits the growth of cancer cells, promotes apoptosis, and inhibits the phosphorylation of eIF4E.

EB1 peptide (Penetrating analog), an amphipathic cell-penetrating peptide (CPP) derivative of Penetratin, holds promise for intracellular drug delivery research [1].

DSPE-PEG2000-EB1 is a PEG compound composed of DSPE and the pH-responsive transmembrane peptide (EB1). It is utilized for drug delivery.

DSPE-PEG1000-EB1 is a PEG compound composed of DSPE and a pH-responsive cell-penetrating peptide (EB1). It is utilized for drug delivery applications.

DSPE-PEG5000-EB1 is a PEGylated compound composed of DSPE and the pH-responsive transmembrane peptide (EB1). It is useful for drug delivery applications.

DSPE-PEG3400-EB1 is a PEG compound formed by combining DSPE with a pH-responsive transmembrane peptide (EB1). It is utilized in drug delivery applications.

Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.

Adenosylcobalamin (AdoCbl) is a biologically active form of vitamin B12 .It is a cofactor for methylmalonyl CoA mutase. It belongs to the corrinoid group of compounds, which contain a corrin macrocycle, and is produced only by certain bacteria and archaea. It is a cofactor for various enzymes including mutases, eliminases, aminomutases, and a reductase.

Nebracetam hydrochloride (WEB 1881 FU hydrochloride) is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i.

WEB-1868 is one of the metabolites of nebracetam which is an agonist for human M1-muscarinic receptors.

Alibendol (cebera) is a choleretic, antispasmodic, and cholekinetic.

Centanafadine is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).

Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).

NPD1335, a potent inhibitor of Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1), exhibits submicromolar activity against T. brucei parasites and an improved cytotoxicity profile. By elevating intracellular cAMP levels, NPD1335 disrupts the cell cycle, leading to cell death [1].

Calystegine B1 is a useful organic compound for research related to life sciences and the catalog number is T126110.

Euchrenone B1 is a useful organic compound for research related to life sciences and the catalog number is T126256.

Trachelosperoside B1 is a useful organic compound for research related to life sciences. The catalog number is T126419 and the CAS number is 109742-56-5.

Nafocare B1 is a modifier of synthetic immune biological response.

Seocalcitol is an analog of vitamin D, binds vitamin D receptor protein from human osteosarcoma MG-63 cells(Kd : 0.27 nM).

EB1002 is a selective NK2R agonist that has demonstrated significant enhancements in the expression levels of genes associated with mitochondrial biogenesis (such as PGC-1α) in obese mice. This suggests that EB1002 promotes energy expenditure by enhancing mitochondrial activity. Additionally, EB1002 has improved insulin sensitivity and glucose-lipid metabolism in mice. Therefore, EB1002 holds potential for research into obesity and type 2 diabetes.

Boronophenylalanine B-10 (BPA) is a boron delivery agent used in boron neutron capture therapy (BNCT) for the treatment of metastatic melanoma and other tumors.

Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).

MLEB-1934 is an effective ergoline alkaloid analogue that acts as a DNA replication inhibitor and is applicable for antibacterial research.

insulin receptor (IR) activator