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Cat No. | Product Name | Synonyms | Targets |
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TP1484L | α2β1 Integrin Ligand Peptide acetate | α2β1 Integrin Ligand Peptide acetate (134580-64-6) | Integrin |
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor. α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the... | |||
T13473 | αvβ1 integrin-IN-1 | Integrin | |
αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects. | |||
T36291 | Integrin modulator 1 | ||
Integrin modulator 1 is a potent and selective α4β1 integrin agonist, with an IC50 of 9.8 nM for RGD-binding α4β1. Integrin modulator 1 increases cell adhesion mediated by α4β1 integrin, with an EC50 of 12.9 nM[1]. Integ... | |||
T40361 | Integrin Binding Peptide | ||
Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels. | |||
T40243 | αvβ5 integrin-IN-1 | ||
αvβ5 integrin-IN-1, a potent and selective αvβ5 integrin inhibitor, exhibits a high inhibitory potency with a pIC50 value of 8.2. | |||
T15584 | Integrin Antagonists 27 | Others | |
Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent. | |||
T11663 | Integrin-IN-2 | Others | |
Integrin-IN-2 is an orally bioavailable pan αv integrin inhibitor.Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively. | |||
TP1484 | α2β1 Integrin Ligand Peptide | ||
The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen recep... | |||
T13473L | αvβ1 integrin-IN-1 TFA (1689540-62-2 free base) | αvβ1 integrin-IN-1 TFA | Integrin |
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM). | |||
TP1374 | α2β1 Integrin Ligand Peptide TFA | ||
α2β1 Integrin Ligand Peptide TFA interacts with the integrin receptor on the cell membrane and enters the cell to mediate extracellular signaling.It is a potential antagonist of the collagen receptor. | |||
T79140 | αvβ6 integrin inhibitor 2 | Integrin | |
αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM. | |||
T82063 | Integrin signaling inhibitor, mP13 | ||
Integrin Signaling Inhibitor mP13 is a compound that impedes both inside-out and outside-in integrin-mediated signaling processes, such as fibrinogen binding, platelet adhesion, and clot retraction [1]. | |||
T79792 | αvβ1 integrin-IN-2 | Integrin | |
αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively. Additionally, this compound inhibits a range of other integrins, with IC50 valu... | |||
T79918 | α7β1 integrin modulator-1 | Integrin | |
α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1]. | |||
T63868 | α5β1 integrin agonist-1 | ||
α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death. | |||
T12177 | Natalizumab | Integrin | |
Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. | |||
T73625 | αvβ1 integrin-IN-1 TFA | ||
αvβ1 Integrin-IN-1 TFA (Compound C8) is a potent, selective inhibitor of αvβ1 integrin, demonstrating an IC 50 value of 0.63 nM. It exhibits antifibrotic effects [1]. | |||
T16695 | Pyrintegrin | Integrin | |
Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal... | |||
T6812L | Cyclo(-RGDfK) TFA | Integrin | |
Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM). | |||
TP1330 | Cyclo(RADfK) | Integrin | |
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.Cyclo(RADfK) is a negative control for the cyclo (-RGDfK-), the RGD peptide. RGD... | |||
T6812 | Cyclo(-RGDfK) | Cyclo (-RGDfK) | Integrin |
Cyclo(-RGDfK) (Cyclo (-RGDfK)) is an effective and specific αvβ3 integrin inhibitor. | |||
T8523 | ILK-IN-3 | Integrin | |
ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity. | |||
T7261 | Grp94 Inhibitor-1 | GPR , HSP | |
Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM). | |||
T13147 | ICAM-1-IN-1 | Integrin | |
ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor. | |||
TP1204 | IRGD peptide | c(CRGDKGPDC) | Integrin |
iRGD peptide (c(CRGDKGPDC)) is a 9-amino acid cyclic peptide (sequence: CRGDKGPDC) and a molecular mimicry agent that was originally identified in an in vivo screening of phage display libraries in tumor-bearing mice. | |||
T4259 | GLPG0187 | Integrin | |
GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM). | |||
TQ0250 | CWHM-12 | Integrin | |
CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1). | |||
T21868 | BIO-1211 | Integrin | |
BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM). | |||
T6813 | Cyclo(RGDyK) trifluoroacetate | Cyclo(RGDyK) | Integrin |
Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM. | |||
T21781 | A-286982 | Integrin | |
A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1. | |||
TP1474 | LXW7 | Integrin | |
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. LXW7 is a disulfide cyclic octa-pepti... | |||
T2254 | A-205804 | Integrin | |
A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression. | |||
T5488 | ILK-IN-2 | OSU-T315 | Integrin |
ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM. | |||
T12783 | RWJ 50271 | Integrin | |
RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells). | |||
T2494 | Cilengitide | EMD 121974 | Integrin , Autophagy |
Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa. | |||
T3638 | Leukadherin-1 | Integrin , Complement System | |
Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendothelial migration; reduces inflammation. | |||
T30751 | Carotegrast methyl | AJM300 | Integrin |
Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist. | |||
T4400 | DIM-C-pPhOH | CDIM8 | Apoptosis , Others |
DIM-C-pPhOH (CDIM8) is a nur77 (NR4A1) antagonist,inhibits TGF-β induced cell migration of breast cancer cell lines,promotes ROS/endoplasmic reticulum stress and proapoptotic pathways in pancreatic cancer cell lines,mimi... | |||
T5310 | TR-14035 | MDK-1191 | Integrin |
TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM). | |||
T4435 | E7820 | ER68203-00 | Integrin |
E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells). | |||
T10397 | ATN-161 trifluoroacetate salt | ATN-161 TFA salt | Integrin |
ATN-161 trifluoroacetate salt (ATN-161 TFA salt) is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of liver metastases and improves survival in a murine model. | |||
T6966 | RGD | RGD (Arg-Gly-Asp) Peptides,Arg-Gly-Asp,RGD Peptides | Integrin |
RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins. | |||
T5485 | OSU-T315 | OSU-T315 (1,5-regioisomer),ILK-IN-2 | Apoptosis , Integrin , Autophagy |
OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor. | |||
T6182 | Tirofiban | L700462,Aggrastat,MK383 | Integrin |
Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM. | |||
T3977 | Lifitegrast | SHP-606,SAR 1118 | Integrin |
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist. | |||
T6657 | SB273005 | Integrin | |
SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively. | |||
T6806 | Cilengitide TFA | Integrin , Autophagy | |
Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2. | |||
T7570 | RGD peptide (GRGDNP) | RGD peptide GRGDNP(2TFA),RGD peptide GRGDNP | Apoptosis , Integrin |
RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor. | |||
T2537 | Tirofiban hydrochloride monohydrate | Tirofiban Hydrochloride,MK-383 Hydrochloride | ATPase , Integrin |
Tirofiban hydrochloride monohydrate (MK-383 Hydrochloride) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist. | |||
T1950 | PND-1186 | PND1186,PND 1186,VS-4718,SR-2516 | Apoptosis , FAK |
PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3862 | Irigenin | NF-κB , Integrin | |
Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enha... | |||
T3404 | Cucurbitacin B | Cuc B,DATISCACIN,Amarine | Apoptosis , PTEN , Integrin , Endogenous Metabolite , HIF , STAT , Autophagy |
Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inh... | |||
T36715 | Tetrac | Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid | Apoptosis , EGFR |
Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blocking EGFR-mediated cell signaling in colorectal cancer cells.Tetrac... | |||
T3834 | 8-Epideoxyloganic acid | ROS , Immunology/Inflammation related | |
8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibl... | |||
T5S0055 | Chelidonine | Helidonine,Khelidonin,Stylophorin | Apoptosis , Others , Influenza Virus |
1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model ... | |||
T4S0498 | Glaucocalyxin A | Wangzaozin B,Leukamenin F | Apoptosis , Akt , Caspase , PI3K |
1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi... | |||
TN5447 | Apigenin 7-O-methylglucuronide | Apigenin-7-O-β-D-glucuronide methyl ester | |
Apigenin 7-O-methylglucuronide did not affect GAG level or secretion, may potentially be used in osteogenesis imperfecta (OI) type I pharmacotherapy in patients with normal GAG content. Apigenin 7-O-methylglucuronide whi... | |||
T40960 | Fibronectin | Integrin | |
Fibronectin is a macromolecular glycoprotein found in blood, connective tissue, and cell surfaces that serves as a biomarker for tissue damage.Fibronectin is recognized by the integrin family of surface receptors.Fibrone... | |||
T36295 | Echistatin TFA | ||
Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorpti... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05716 | Integrin alpha V beta 3 Protein, Human, Recombinant (His) | Human | HEK293 |
Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. | |||
TMPY-05717 | Integrin alpha V beta 8 Protein, Human, Recombinant (His) | Human | HEK293 |
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cyto... | |||
TMPY-04643 | Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His) | Mouse | HEK293 |
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th... | |||
TMPY-03878 | Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) | Human | HEK293 |
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th... | |||
TMPY-02159 | Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His) | Human | HEK293 |
Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 192 kDa. Accession number: P08648&P05556-1 | |||
TMPY-02160 | Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His) | Human | HEK293 |
Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 196 kDa. Accession number: P53708&P05556-1 | |||
TMPY-04881 | Integrin alpha 6 beta 4 Protein, Human, Recombinant (Flag & His) | Human | HEK293 |
Integrin alpha 6 beta 4 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 196 kDa. Accession number: CAA37656.1 | |||
TMPY-02158 | Integrin alpha 6 beta 1 Protein, Human, Recombinant (Flag & His) | Human | HEK293 |
Integrin alpha 6 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 198 kDa. Accession number: P23229-3&P05556-1 | |||
TMPY-05762 | Integrin alpha X beta 2 Protein, Human, Recombinant (His) | Human | HEK293 |
Integrin alpha X beta 2 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 204.8 kDa. Accession number: P20702&P05107 | |||
TMPY-02161 | Integrin alpha X beta 2 Protein, Human, Recombinant (Flag & His) | Human | HEK293 |
Integrin alpha X beta 2 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 205 kDa. Accession number: P20702&P05107 | |||
TMPY-00476 | ITGB1 Protein, Human, Recombinant (His) | Human | HEK293 |
ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involv... | |||
TMPJ-00211 | CD47 Protein, Human, Recombinant (His) | Human | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an... | |||
TMPK-00839 | ITGB6 Protein, Human, Recombinant (His) | Human | HEK293 |
ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide ... | |||
TMPK-01247 | ITGB6 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide ... | |||
TMPJ-00810 | ITGA5 Protein, Human, Recombinant (His) | Human | Human Cells |
Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In cas... | |||
TMPY-02289 | CIB2 Protein, Human, Recombinant (His) | Human | E. coli |
Calcium and integrin-binding protein 2 (CIB2) belongs to a protein family with four known members, CIB1 through CIB4, which are characterized by multiple calcium-binding EF-hand domains. Sensorineural hearing loss is gen... | |||
TMPJ-00786 | ITGB1 Protein, Human, Recombinant (aa 21-728, His) | Human | Human Cells |
Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue ... | |||
TMPY-02198 | ILKAP Protein, Human, Recombinant (His) | Human | HEK293 |
Integrin-linked kinase-associated serine/threonine phosphatase 2C, also known as ILKAP, is a cytoplasm protein that belongs to the PP2C family. ILKAP contains one PP2C-like domain. ILKAP is widely expressed. Highest leve... | |||
TMPJ-00614 | CD47 Protein, Rhesus macaque, Recombinant (His & Flag) | Rhesus Macaque | Human Cells |
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellular domain (ECD)... | |||
TMPJ-00212 | CD47 Protein, Human, Recombinant (mFc) | Human | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an... | |||
TMPJ-00613 | CD47 Protein, Rhesus macaque, Recombinant (hFc) | Rhesus macaque | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an... | |||
TMPJ-00445 | IBSP Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Bone sialoprotein 2(IBSP) is a monomeric non‑collagenous member of the SIBLING family of extracellular matrix proteins. It is principally associated with the early stages of bone mineralization. Mouse IBSP is synthesize... | |||
TMPJ-00208 | CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an... | |||
TMPJ-00209 | CD47 Protein, Human, Recombinant (Avi & His), Biotinylated | Human | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an... | |||
TMPJ-00242 | PARVA Protein, Human, Recombinant (His) | Human | E. coli |
Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with i... | |||
TMPH-00213 | Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc) | Bothrops atrox | E. coli |
Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor a... | |||
TMPH-02569 | WISP2/CCN5 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production. | |||
TMPY-00970 | CD31/PECAM-1 Protein, Human, Recombinant (His) | Human | HEK293 |
The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transm... | |||
TMPY-03630 | MZB1/PERP1 Protein, Human, Recombinant (His) | Human | HEK293 |
MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion an... | |||
TMPY-01613 | Periostin/OSF-2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ... | |||
TMPY-01020 | Periostin/OSF-2 Protein, Human, Recombinant (His) | Human | HEK293 |
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ... | |||
TMPY-04935 | CD47 Protein, Human, Recombinant (aa 1-139, His) | Human | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-04683 | CD47 Protein, Human, Recombinant | Human | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-03093 | CD47 Protein, Rat, Recombinant (His) | Rat | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-05191 | CD47 Protein, Human, Recombinant, Biotinylated | Human | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-05276 | CD47 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-04810 | CD47 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-05343 | CD47 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem... | |||
TMPY-01142 | ICAM-1/CD54 Protein, Human, Recombinant (His) | Human | HEK293 |
Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. IC... | |||
TMPY-04487 | Osteomodulin Protein, Human, Recombinant (His) | Human | HEK293 |
Osteomodulin (OMD), also known as Osteoadherin (OSAD), Keratan sulfate proteoglycan osteomodulin, KSPG osteomodulin, and SLRR2C, is a secreted protein that belongs to the small leucine-rich proteoglycan (SLRP) family and... | |||
TMPY-01349 | ICAM-1/CD54 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. IC... | |||
TMPY-05017 | ICAM-1/CD54 Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. IC... | |||
TMPY-00981 | ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK) | Human | HEK293 |
Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. IC... | |||
TMPY-01830 | VCAM-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains... | |||
TMPY-00947 | VCAM-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains... | |||
TMPY-01288 | Osteopontin Protein, Human, Recombinant (His) | Human | HEK293 |
Osteopontin, also known as Secreted phosphoprotein 1, Bone sialoprotein 1, BSP-1, OPN, and SPP1, is a member of the osteopontin family and a SIBLING glycoprotein. Osteopontin has been classified as T-helper 1 cytokine an... | |||
TMPY-06988 | Osteopontin Protein, Human, Recombinant (aa 17-166, His) | Human | HEK293 |
Osteopontin, also known as Secreted phosphoprotein 1, Bone sialoprotein 1, BSP-1, OPN, and SPP1, is a member of the osteopontin family and a SIBLING glycoprotein. Osteopontin has been classified as T-helper 1 cytokine an... | |||
TMPY-00803 | Fibronectin Protein, Human, Recombinant (aa 607-1265, His) | Human | HEK293 |
Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet ... | |||
TMPY-05053 | ANGPTL2 Protein, Human, Recombinant (His) | Human | HEK293 |
The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism... | |||
TMPY-01919 | MMP-9 Protein, Mouse, Recombinant | Mouse | HEK293 |
Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogen... | |||
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