T13406L |
Zabofloxacin hydrochloride
|
623574-00-5
|
98%
|
|
Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens inc...
|
T15804 |
LY2452473
|
1029692-15-6
|
98%
|
|
LY2452473 is an orally bioavailable and selective androgen receptor modulator.
|
T40284 |
B-Raf IN 2
|
2649372-20-1
|
98%
|
|
B-Raf IN 2 is a potent and selective BRAF inhibitor extracted from patent WO2021116055A1, compound Ia. B-Raf IN 2 can be used for the research of cancer.
|
TN4166 |
Griffipavixanthone
|
219649-95-3
|
98%
|
|
Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mito...
|
T6318 |
AZ 628
|
878739-06-1
|
98%
|
|
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.
|
T8721 |
I-37
|
2359690-13-2
|
98%
|
|
I-37 is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibitor.
|
T6003 |
GSK1904529A
|
1089283-49-7
|
98%
|
|
GSK1904529A is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .
|
T10567 |
BMS-214662
|
195987-41-8
|
98%
|
|
BMS-214662 is an effective and selective inhibitor of farnesyl transferase with potent antitumor activity (IC50: 1.35 nM).
|
T1931 |
6H05
|
1469338-01-9
|
98%
|
|
6H05 is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).
|
T12556 |
PROTAC B-Raf degrader 1
|
2364367-27-9
|
98%
|
|
PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.
|
TN2114 |
Pseudoginsenoside Rh2
|
1370264-16-6
|
98%
|
|
Pseudoginsenoside Rh2 has cytotoxicity, it induces mitochondrial apoptosis in A549 cells and is responsible for excessive activation of the Ras/Raf/ERK/p53 pathw...
|
T12978 |
NSC-70220
|
4551-00-2
|
98%
|
|
SOS1-IN-1 is an inhibitor of SOS1.
|
T2074 |
Raf inhibitor 1
|
1093100-40-3
|
98%
|
|
B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor.
|
T24437 |
MCP110
|
521310-51-0
|
98%
|
|
MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.
|
T9755 |
MRTX0902
|
2654743-22-1
|
98%
|
|
MRTX0902 is an effective and high selective inhibitor of SOS1 with an IC50 of 46 nM and a Ki of 2 nM.
|
T6949 |
PLX7904
|
1393465-84-3
|
98%
|
|
PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melan...
|
T6320 |
GDC-0879
|
905281-76-7
|
98%
|
|
GDC-0879 is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM with activity against c-Raf as well.
|
T19802 |
ZINC72115182
|
918504-27-5
|
98%
|
|
ZINC72115182 is a novel inhibitor of selective. It is the DFG-in over the DFG-out Conformation of the B-Raf Kinase V600E Mutant in Colorectal Cancer.
|
T11224 |
Rineterkib
|
1715025-32-3
|
98%
|
|
ERK-IN-1 is a RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is pa...
|
T10599 |
BRAF inhibitor
|
918505-61-0
|
98%
|
|
BRAF inhibitor is an inhibitor of B-Raf extracted from patent WO/2011103196 A1 (Compound P-0850).
|