NOS

Nitric oxide synthases(NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO is an important cellular signaling molecule. It helps modulate vascular tone, insulin secretion, airway tone, and peristalsis, and is involved in angiogenesis and neural development. It may function as a retrograde neurotransmitter. Nitric oxide is mediated in mammals by the calcium-calmodulin controlled isoenzymes eNOS (endothelial NOS) and nNOS (neuronal NOS).

Cat. No.	Product name	CAS No.	Purity
TN4383	Kazinol U	1238116-48-7	98%
TN4383	Kazinol U may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes by blocking the NF-ÎºB pathway in pancreatic β-cells reduces ce...
T3P2855	Chamigrenal	19912-84-6
T3P2855	β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 m...
T3426	Bacoside A	11028-00-5
T3426	Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotect...
TN1109	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid	168293-14-9
TN1109	3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid shows anti-inflammatory activity, it can inhibit NO production and iNOS expression in LPS-stimulated Raw264.7...
TN1058	Pelargonidin chloride	134-04-3
TN1058	Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels t...
TN5192	Tuberosin	41347-45-9	98%
TN5192	Tuberosin shows anti-inflammatory and antioxidant activities.It demonstrated a significantly potent inhibition on yeast α-glucosidase in a dose dependent manner....
TN5248	Voleneol	70389-88-7	98%
TN5248	1β,6α-Dihydroxyeudesm-4(15)-ene (Voleneol,DE) can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells, it also can dose-dependent...
TN3366	Ailanthoidol	156398-61-7	98%
TN3366	Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock. It also possesses potentia...
TN3635	Chlojaponilactone B	1449382-91-5	98%
TN3635	Chlojaponilactone B has anti-inflammatory activity, it exhibits pronounced inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264...
TN5164	Trans-Hinokiresinol	17676-24-3	98%
TN5164	Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphyla...
TN4038	Eupatolide	6750-25-0	98%
TN4038	Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast can...
TN3587	Capillarisin	56365-38-9	98%
TN3587	Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
TN2095	Pomiferin	572-03-2	98%
TN2095	Pomiferin is a natural product inhibitor of carbonic anhydrase I and II isoenzymes. It has anticancer, antibacterial and antidiabetic properties. Pomiferin has a...
TN4633	Neocryptotanshinone II	27468-20-8	98%
TN4633	Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-ÎºB and iNOS signaling pathways.
T16830	S-MTC	156719-41-4	98%
T16830	S-MTC is a selective inhibitor of type I nitric oxide synthase.
TN1890	Lupeol acetate	1617-68-1	98%
TN1890	Lupeol acetate possesses antinociceptive, antifertility, and anti-inflammatory properties, the effect probably involves the opioid system, as indicated by the co...
TN1171	6-Dehydrogingerdione	76060-35-0	98%
TN1171	1-Dehydro-6-gingerdione is a 5-HT1A receptor partial agonist.
TN1623	Escin IIB	158800-83-0	98%
TN1623	Escin IIB has positive effects on acute inflammation in animals, it can inhibit the induced by serotonin in rats, the hind paw edema induced by carrageenin, and ...
TN5186	Triptoquinone A	142950-86-5	98%
TN5186	Triptoquinone A may be a useful candidate for the development of a drug as a potent inhibitor of iNOS gene over-expression. Triptoquinone A has anti-inflammatory...
T13628	Curvularin	10140-70-2	98%
T13628	Curvulin, naturally isolated from Campylobacter curvulans, is a fungal metabolite and a potent mycotoxin that inhibits cytokine-induced nitric oxide synthase (iN...