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Metabolism AhR

AhR

The aryl hydrocarbon receptor (AHR) is a member of the basic helix-loop-helix-period-aryl hydrocarbon receptor nuclear translocator-single-minded (bHLH-PAS) family of transcription factors, which act as biological sensors by initiating gene expression programs in response to endogenous and exogenous signals.
Cat No. product name
T0343 Nimodipine Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
T1046 Mexiletine hydrochloride Mexiletine Hydrochloride is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine....
T1159 Leflunomide Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.
T1831 StemRegenin 1 StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor.
T1960 YL109 YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.
T2448 CH 223191 CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).
T4644 Benvitimod Tapinarof is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.
T4938 Indoxyl sulfate potassium salt Indoxyl sulfate (potassium salt) is an agonist for the human aryl hydrocarbon receptor (AHR). The aryl hydrocarbon receptor (AhR) has recently emerged as a path...
T4928 L-Kynurenine L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppres...
T5622 AHR antagonist 1 AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
T7202 ITE ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.
T5541 PDM 11 PDM 11 is an antagonist of aryl hydrocarbon receptor (AhR)
T10007 1,4-Chrysenequinone 1,4-Chrysenequinone acts as an activator of aryl hydrocarbon receptor (AhR).
T9112 (-)-Perillaldehyde (-)-Perillaldehyde shows antibacterial activity.
T5281 3-Methylindole Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
T5281 3-Methylindole Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
T4608 PDM2 PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
T4607 CAY10465 CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
T4607 CAY10465 CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
TN1451 Brevifolincarboxylic acid Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincar...
Nimodipine
T0343CAS 66085-59-4
Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
Mexiletine hydrochloride
T1046CAS 5370-01-4
Mexiletine Hydrochloride is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine....
Leflunomide
T1159CAS 75706-12-6
Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.
StemRegenin 1
T1831CAS 1227633-49-9
StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor.
YL109
T1960CAS 36341-25-0
YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.
CH 223191
T2448CAS 301326-22-7
CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).
Benvitimod
T4644CAS 79338-84-4
Tapinarof is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.
Indoxyl sulfate potassium salt
T4938CAS 2642-37-7
Indoxyl sulfate (potassium salt) is an agonist for the human aryl hydrocarbon receptor (AHR). The aryl hydrocarbon receptor (AhR) has recently emerged as a path...
L-Kynurenine
T4928CAS 2922-83-0
L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppres...
AHR antagonist 1
T5622CAS 2162982-11-6
AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
ITE
T7202CAS 448906-42-1
ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.
PDM 11
T5541CAS 1032508-03-4
PDM 11 is an antagonist of aryl hydrocarbon receptor (AhR)
1,4-Chrysenequinone
T10007CAS 100900-16-1
1,4-Chrysenequinone acts as an activator of aryl hydrocarbon receptor (AhR).
(-)-Perillaldehyde
T9112CAS 18031-40-8
(-)-Perillaldehyde shows antibacterial activity.
3-Methylindole
T5281CAS 83-34-1
Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
3-Methylindole
T5281CAS 83-34-1
Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
PDM2
T4608CAS 688348-25-6
PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
CAY10465
T4607CAS 688348-33-6
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
CAY10465
T4607CAS 688348-33-6
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
Brevifolincarboxylic acid
TN1451CAS 18490-95-4
Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincar...