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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3036 | Dydrogesterone | Progesterone Receptor | |
Dydrogesterone is a potent progestogen which can be used in progesterone deficiency studies. | |||
T7537 | Norgestimate | Progesterone Receptor | |
Norgestimate is an acetylated progestinused in combination with ethinyl estradiol as an oral contraceptive. | |||
T13703 | Gestonorone Capronate | Prostaglandin Receptor | |
Gestonorone Capronate is a progesterone used to treat benign prostatic hyperplasia and endometrial cancer. | |||
T28362 | PF-02413873 | PF02413873 | Progesterone Receptor |
PF-02413873 is a competitive antagonist of nonsteroidal progesterone receptor with a Ki of 2.6 nM. PF-02413873 can be used in studies about the treatment of gynecological conditions such as endometriosis. | |||
T1514 | Norethindrone | Norethisterone | Estrogen/progestogen Receptor , Progesterone Receptor |
Norethindrone (Norethisterone) is a synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties... | |||
T14151 | AKR1C1-IN-1 | NADPH | |
AKR1C1-IN-1 is a human 20α-hydroxysteroid dehydrogenase (AKR1C1) inhibitor (Ki: 4 nM for AKR1C1). | |||
T36912 | 17α,20β-Dihydroxy-4-pregnen-3-one | 17α,20β-dihydroxy Progesterone,17α,20β-DHP,17α,20β-Dihydroxy-4-pregnen-3-one | |
17α,20β-Dihydroxy-4-pregnen-3-one (17α,20β-DHP) is an endogenous, maturation-inducing steroid that stimulates oocyte maturation in females of several teleost species. For example, 1 μg/ml of 17α,20β-DHP applied to Persia... | |||
T8395 | Nomegestrol acetate | Others , Progesterone Receptor | |
Nomegestrol acetate is a widely used progestin-like drug,which is characterized as a full agonist at the progesterone receptor | |||
T1596 | Chlormadinone acetate | Gestafortin | Progesterone Receptor , Androgen Receptor |
Chlormadinone acetate (Gestafortin) is an orally active synthetic progestational hormone used often in combinations as an oral contraceptive. | |||
T1541 | Drospirenone | ZK 3059,Dihydrospirorenone | Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , Androgen Receptor , COX |
Drospirenone (ZK 3059) is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity. | |||
T7556 | Fadrozole hydrochloride | CGS 16949A | Aromatase |
Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish. | |||
T6819 | Desogestrel | Org-2969,Desogen,Desogestrelum,Cerazette | Estrogen/progestogen Receptor , Progesterone Receptor |
Desogestrel (Cerazette) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents. | |||
T0996 | Ethynodiol diacetate | Ethynodiol acetate,8080 CB | Estrogen/progestogen Receptor , Progesterone Receptor |
Ethynodiol diacetate (Ethynodiol acetate) is a synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. | |||
T6713 | Ulipristal | Estrogen/progestogen Receptor , Progesterone Receptor | |
Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure. | |||
T2577 | Dienogest | STS 557 | Apoptosis , Estrogen/progestogen Receptor , Progesterone Receptor , Autophagy |
Dienogest (STS 557) is an orally-active, semisynthetic, fourth generation, nonethinylated progestogen with antiproliferative, antiandrogenic, anti-inflammatory and antiangiogenic activities that is used in hormone therap... | |||
T1490 | Gestodene | SHB 331,WL 70 | Estrogen/progestogen Receptor , Progesterone Receptor |
Gestodene (WL 70) is a progestogen hormonal contraceptive. | |||
T5174 | Nestoron | ST-1435,Segesterone Acetate,Nestorone,Elcometrine | Estrogen/progestogen Receptor , Progesterone Receptor |
Nestoron (Segesterone Acetate), a synthetic progestin, is a high-affinity agonist of the progesterone receptor (EC50: 10.3 nM). | |||
T0870 | Altrenogest | R2267,RU2267,Allyltrenbolone,A35957 | Estrogen/progestogen Receptor , Progesterone Receptor |
Altrenogest (Allyltrenbolone)(A35957; RU2267), a progestogen, has structural relation with veterinary steroid trenbolone. | |||
T14975 | CJ-42794 | CJ-042794 | Others |
CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4). It inhibits [3H]-PGE2 binding to the human EP4 receptor (a mean pKi: 8.5). CJ-42794 is a binding affinity that was at least 200-... | |||
T2527 | Ulipristal acetate | Ulipristal,CDB-2914 | Estrogen/progestogen Receptor , Progesterone Receptor , Autophagy |
Ulipristal acetate (CDB-2914) is an orally bioavailable, acetate salt of ulipristal, a selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereb... | |||
T5317 | Cridanimod | CMA,XBIO-101,10-carboxymethyl-9-acridanone | Progesterone Receptor , STING , IFNAR |
Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. | |||
T2567 | Etonogestrel | 3-Oxodesogestrel,3-keto-Desogestrel,Nexplanon,Implanon | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Progesterone Receptor , Endogenous Metabolite |
Etonogestrel (Implanon) is a steroidal progestin used as hormonal contraceptives. | |||
T1102 | Mifepristone | C-1073,RU486,RU 38486 | Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , NO Synthase , Autophagy |
Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist. | |||
T2231 | Estradiol dipropionate | 17-Beta-Estradiol-3,17-Dipropionate | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Progesterone Receptor |
Estradiol dipropionate (17-Beta-Estradiol-3,17-Dipropionate) is a synthetic ester, specifically the 3, 17-dipropanoyl ester, of the natural estrogen, estradiol. | |||
T20720 | Norethisterone enanthate | NSC 9564,Norethindrone enanthate,LG-202,LG202,NSC9564,LG 202,NSC-9564 | Estrogen/progestogen Receptor |
Norethisterone enanthate (NSC-9564) is a long-acting parenteral progestogen with antigonadotropic effects. | |||
T6858 | Hydroxyprogesterone caproate | Primolut Depot,Delalutin,Hormofort,17α-Hydroxyprogesterone hexanoate,17α-Hydroxyprogesterone caproate | Autophagy |
Hydroxyprogesterone caproate (Delalutin) is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical m... | |||
T40380 | 17α-Hydroxyprogesterone acetate | Others | |
17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate shows antiinflammatory effects at the murine maternal-fetal interface. | |||
T37319 | 5β-Dihydroprogesterone | ||
5β-Dihydroprogesterone (5β-DHP) is a progesterone receptor agonist and metabolite of progesterone .1,2It is formed from progesterone by 5β-reductase.25β-DHP inhibits spontaneous contractions in isolated rat uterus when u... | |||
T19416 | Medroxyprogesterone acetate D3 | MPA D3,Medroxyprogesterone 17-acetate D3 | Others |
Medroxyprogesterone acetate D3 is deuterium labeled Medroxyprogesterone acetate. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors. | |||
T34302 | Retroprogesterone | ||
Retroprogesterone, a progestin, may be used for menstrual irregularities in adolescence, for the maintenance of threatened pregnancy, and possibly as an ovulation stimulant. | |||
T21335 | Fluorogestone acetate | Flurogestone Acetate Flugestone Acetate Fluorogesterone Acetate SC9880 | Others |
Fluorogestone acetate (Flurogestone Acetate Flugestone Acetate Fluorogesterone Acetate SC9880) showed a high potency with short duration of activity and performed physiologically similar to progesterone. FGA was approxim... | |||
T60056 | Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl- | Progesterone Receptor | |
Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl- is a progesterone receptor antagonist with antiprogestin effects. | |||
T35054 | Vilaprisan | BAY 1002670,BAY10-02670,BAY-1002670,BAY1002670,BAY-10-02670,BAY 10-02670 | Progesterone Receptor |
Vilaprisan (BAY 1002670) is a novel orally available and selective progesterone receptor modulator (SPRM) with antiproliferative activity against uterine fibroids (UF) and can be used for the study of uterine fibroids. | |||
T68664 | Epostane | Win-32729 | Dehydrogenase |
Epostane (Win-32729) is a 3β-hydroxysteroid dehydrogenase inhibitor that acts by inhibiting the enzyme 3β-hydroxysteroid dehydrogenase, blocking progesterone production. | |||
T61864 | Melengestrol acetate | Progesterone Receptor | |
Melengestrol acetate is a derivative of progesterone and acts as a corticosteroid hormone. Melengestrol acetate promotes endometrial proliferation delay of menstrual activity and pregnancy maintenance. | |||
TP1862L | [Sar9] Substance P acetate(77128-75-7 free base) | Neurokinin receptor | |
[Sar9]-Substance P acetate is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP. | |||
T25048 | Algestone acetophenide | Neolutin | Others |
Algestone acetophenide (Neolutin) is progesterone that used in estrus synchronization and has been evaluated as an injectable contraceptive in combination with estradiol enanthate. It is also used therapeutically as a to... | |||
T21395 | Finerenone | BAY948862,BAY-948862,BAY94-8862,BAY 94-8862,BAY-94-8862,BAY 948862 | Glucocorticoid Receptor |
Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862... | |||
T35666 | PRGL493 | Others | |
PRGL493 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4).1It inhibits formation of arachidonoyl-CoA (AA-CoA) from arachidonic acid in, as well as the proliferation and migration of, PC3 and MDA-MB-231 cancer c... | |||
T16502 | PF-3882845 | Others | |
PF-3882845 also binds to the progesterone receptor (the binding IC50: 310 nM). PF-3882845 is a remarkably high affinity selective and orally efficacious mineralocorticoid receptor (MR binding IC50=2.7 nM) antagonist for ... | |||
T17291 | ZK 216348 | (+)-ZK 216348 | Others |
ZK 216348 also binds to Progesterone and mineralocorticoid receptors (IC50s: 20.4 nM and 79.9 nM, respectively). ZK 216348 is a nonsteroidal selective glucocorticoid receptor agonist (IC50: 20.3 nM). ZK 216348 has an an... | |||
T20747 | Lilopristone | ZK 98.734,ZK-98.734,ZK98.734,Propylmesterolone,Lilopristona,Lilopristonum | |
Lilopristone is an antagonist of progesterone. | |||
T28995 | Tosagestin | Org 30659,Org30659,Org-30659 | |
Tosagestin is a progesterone receptor agonist. | |||
T28361 | PF-02367982 | PF 02367982 | |
PF-02367982 is a potent, selective nonsteroidal progesterone antagonist. | |||
T28263 | Org-31710 | Org 31710,Org31710 | |
Org-31710 is a progesterone receptor antagonist potentially for contraception. | |||
T31608 | EIDD-1619 | ||
EIDD-1619 is a novel water-soluble analog of progesterone. | |||
T29863 | Algestone acetonide | W3395,W-3395,17α-isopropylidenedioxyprogesterone,algestone 16α,17α-acetonide,W 3395 | |
Pyruvate algebra stone (W-3395) is progesterone. | |||
T31082 | CP-8668 | UNII-5371O2R79D,CP 8668 | |
CP-8668 is an orally active nonsteroidal progesterone receptor modulator with tetrahydrobenzoindolone skeleton. | |||
T34798 | Telapristone | metabolite of telapristone acetate (CDB-4124) | |
Telapristone, is the active metabolite of telapristone acetate (also known as CDB-4124). Telapristone is a selective progesterone receptor modulator (SPRM) being studied for the treatment of certain progesterone-sensitiv... | |||
T21257 | 4-Benzoyl-L-phenylalanine | BzF,4 Benzoyl L phenylalanine | |
Algestone is a synthetic dihydroxy derivative of Progesterone, wherein the acetonide group possesses anti-inflammatory properties. |
Cat No. | Product Name | Synonyms | Targets |
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T0478 | Progesterone | Pregn-4-ene-3,20-dione | Estrogen/progestogen Receptor , Progesterone Receptor , Opioid Receptor , Endogenous Metabolite |
Progesterone (Pregn-4-ene-3,20-dione) is the major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is require... | |||
T5040 | Medroxyprogesterone | Estrogen/progestogen Receptor , Progesterone Receptor | |
Medroxyprogesterone is used in the treatment of renal carcinoma. It is a synthetic progestational hormone used in veterinary practice as an estrus regulator. | |||
T1263 | Levonorgestrel | D-Norgestrel | Others , Estrogen/progestogen Receptor , Progesterone Receptor |
Levonorgestrel (D-Norgestrel) is a Progestin and Progestin-containing Intrauterine Device. The physiologic effect of levonorgestrel is by means of Inhibit Ovum Fertilization. | |||
T1429 | 17α-Hydroxyprogesterone | Hydroxyprogesterone,17-OHP,17-Hydroxyprogesterone | Estrogen/progestogen Receptor , Progesterone Receptor , Endogenous Metabolite |
17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to th... | |||
T2899 | Liquiritin | Liquiritigenin-4'-O-glucoside,Liquiritoside | Reactive Oxygen Species |
Liquiritin (Liquiritigenin-4'-O-glucoside) (LIQ) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities. | |||
T1284 | Megestrol acetate | SC10363,BDH1298 | Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , HIV Protease , Autophagy |
Megestrol acetate (BDH1298) is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment ... | |||
T1261 | Medroxyprogesterone Acetate | Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,Farlutin,Medroxyprogesterone (acetate) | Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , Androgen Receptor , Endogenous Metabolite |
Medroxyprogesterone Acetate (Farlutin) is a synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been... | |||
T1688 | Pregnanediol | 5Beta-Pregnane-3Alpha,20alpha-Diol,Pregnandiol | Estrogen/progestogen Receptor , Endogenous Metabolite |
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol(5Beta-Pregnane-3Alpha,20alpha-Diol) has two hydroxyl groups, at 3-alpha a... | |||
T8094 | 16-Dehydroprogesterone | 16-Dehydroprogesterone | Endogenous Metabolite |
16-Dehydroprogesterone is a endogenous Metabolite. 16-Dehydroprogesterone is a steroidal progestin. | |||
TCA2511 | 11Beta-hydroxyprogesterone | Sodium Channel | |
The progesterone derivatives 11 alpha- and 11 beta-hydroxyprogesterone are potent inhibitors of 11 beta-hydroxysteroid dehydrogenase (isoforms 1 and 2) in vitro and can confer mineralocorticoid activity on corticosterone... | |||
T5556 | 5a-Pregnane-3,20-dione | Endogenous Metabolite | |
5a-Pregnane-3,20-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone | |||
T13518 | 5α-Pregnane-3β,6α-diol-20-one | Others | |
5α-Pregnane-3β,6α-diol-20-one is a mitogenic metabolite derived from progesterone, capable of being synthesized by androgen-responsive prostate cancer cells under conditions of starvation. | |||
T7974 | Lynestrenol | Progesterone Receptor | |
Lynestrenol is a synthetic progestational hormone, is the progesterone receptor agonist | |||
T64744 | Ovalbumins | Endogenous Metabolite | |
Ovalbumins is the main protein found in egg whites. Ovalbumins have various biological activities such as antibacterial, anticancer, antihypertensive, antioxidant and immunomodulatory activities. Ovalbumins are the most ... | |||
T7931 | 16a,17a-Epoxy-4-Pregnen-3,20-Dione | Others | |
16a,17a-Epoxy-4-Pregnen-3,20-Dione is a synthetic progestin, a metabolite of the luteinizing hormone hormone, which acts by binding to the luteinizing hormone receptor. It has been used to study the effects of progestero... | |||
TN6524 | Irilone | ||
Irilone has immunomodulatory, and α-amylase inhibitory activities, it exhibits the selective inhibition toward CYP3 A4 rather than other major human CYPs. Irilone exhibited prominent antioxidant activities with the IC50 ... |
Cat No. | Product Name | Species | Expression System |
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TMPY-02412 | ENO1 Protein, Human, Recombinant (His) | Human | E. coli |
The ENO1 gene encodes a multifunctional enzyme that has been identified as a key component of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value ... | |||
TMPK-00717 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag) | Human | HEK293 |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK ... | |||
TMPK-00591 | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) | Mouse | HEK293 |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK ... | |||
TMPH-02141 | CYP21A2 Protein, Human, Recombinant (His) | Human | Yeast |
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-d... | |||
TMPY-01383 | PRMT6 Protein, Human, Recombinant (His & Flag) | Human | HEK293 |
Protein arginine N-methyltransferase 6, also known as Histone-arginine N-methyltransferase PRMT6, PRMT6, and HRMT1L6, is a member of the protein arginine N-methyltransferase family and PRMT6 subfamily. PRMT6 is highly ex... | |||
TMPH-01793 | NR1I2 Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentia... | |||
TMPK-00716 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244) | Human | HEK293 |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK ... | |||
TMPH-02140 | CYP21A2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-d... | |||
TMPH-00279 | Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (His) | Bovine | Yeast |
Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-... | |||
TMPH-00851 | HSD3B1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
A bifunctional enzyme responsible for the oxidation and isomerization of 3beta-hydroxy-Delta(5)-steroid precursors to 3-oxo-Delta(4)-steroids, an essential step in steroid hormone biosynthesis. Specifically catalyzes the... | |||
TMPH-00278 | Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (E. coli, His) | Bovine | E. coli |
Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-... | |||
TMPH-02139 | CYP17A1 Protein, Human, Recombinant (GST) | Human | E. coli |
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen sy... | |||
TMPY-00073 | ENO1 Protein, Rat, Recombinant (His) | Rat | E. coli |
The ENO1 gene encodes a multifunctional enzyme that has been identified as a key component of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value ... | |||
TMPY-02138 | Uteroglobin Protein, Human, Recombinant (His) | Human | HEK293 |
Uteroglobin (UG), also known as Secretoglobin 1A member 1 (SCGB1A1), Blastokinin, Clara cell secretor protein (CCSP) or Clara cell-specific 10-kDa protein (CC10), is the founding member of the secretoglobin family of sma... | |||
TMPY-02328 | Uteroglobin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Uteroglobin (UG), also known as Secretoglobin 1A member 1 (SCGB1A1), Blastokinin, Clara cell secretor protein (CCSP) or Clara cell-specific 10-kDa protein (CC10), is the founding member of the secretoglobin family of sma... |
Cat No. | Product Name | ||
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L2191 | Anti-Breast Cancer Compound Library | 1965 compounds | |
A unique collection of 1965 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study; |