mes

MES (2-Morpholinoethanesulphonic acid) potassium is a zwitterionic buffer with an effective pH buffering range of 5.5-7.0. As a Good's buffer, MES potassium is widely used in biochemical and molecular biology experiments, including cell culture, enzyme activity assays, electrophoresis, and protein studies.

MES Sodium is a biological buffer commonly used to prepare solutions with a pH range of 5.5–6.7.

MES (2-Morpholinoethanesulphonic acid) hydrate is a zwitterionic buffer with an effective buffering range of pH 5.5-7.0. As a Good's buffer, MES hydrate is extensively used in biochemical and molecular biology experiments, including applications such as cell culture, enzyme activity assays, electrophoresis, and protein research.

MES (2-Morpholinoethanesulphonic acid) (2-Morpholinoethanesulphonic acid), a zwitterionic buffer, is effective in the pH range of 5.5-7.7. MES, as one of the Good's buffers, is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments.

Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.

Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor

2-Methylthio-ATP tetrasodium (2-MeS-ATP tetrasodium) is a non-specific P2 receptor agonist, which can activate P2X2 and P2Y1 receptors and mimic the physiological effects of ATP by binding to P2 receptors, and is widely used in the study of cell signaling and metabolic processes. In addition, 2-Methylthio-ATP tetrasodium induces non-competitive inhibition of ADP-induced platelet aggregation in human.

2-Methylthioadenosine diphosphate trisodium (2-MeS-ADP) is the salt form of 2-Methylthioadenosine diphosphate, a synthetic analog of adenosine diphosphate (ADP), a potent purinergic P2Y receptor agonist that agonizes human P2Y13 at nanomolar levels, mouse P2Y13 and human P2Y12, induces platelet aggregation and morphological changes, and is indicated for neurological and cardiovascular disease studies.

MES hemisodium salt is a useful organic compound for research related to life sciences. The catalog number is T65286 and the CAS number is 117961-21-4.

2-MeS-ATP (2-Methylthio-ATP) is an analog of adenosine nucleotides, serving specifically as an agonist for P2Y purinergic receptors (P2Y purinergic receptor). This compound also inhibits the release of toxic mediators by macrophages stimulated by lipopolysaccharides (LPS). It is utilized in research related to endotoxic shock and inflammatory diseases.

MES-d13 is the deuterated form of MES. MES (2-Morpholinoethanesulphonic acid) serves as a zwitterionic buffer with an effective buffering range of pH 5.5-7.0. As a Good's buffer, MES is extensively used in biochemistry and molecular biology experiments, including cell culture, enzyme activity assays, electrophoresis, and protein research.

Mes-PEG2-CH2-t-butyl ester is a PEG linker that features a PEG2 segment to enhance compound solubility and a t-butyl ester group that can be deprotected under acidic conditions. The mesylate ester serves as an excellent leaving group, offering all its benefits while not being restricted by acidic protons that could react with nucleophiles.

MES monohydrate is an amphoteric ionic buffer that is a PH stabilizing reagent used for protein purification and enzyme assays.

[11C]MeS-IMPY exhibits a higher binding affinity for β-amyloid plaques extracted from Alzheimer's disease (AD) brains or AD brain homogenates than IMPY, with Ki values of 7.93 nM and 8.95 nM, respectively. [11C]MeS-IMPY is a potential radioactive ligand for positron emission tomography (PET) imaging of β-amyloid plaques.

Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR, respectively).

Deferoxamine Mesylate (DFOM) is an iron chelator and ferroptosis inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1α levels and induces apoptosis.

Darbufelone mesylate (CI-1004 mesylate) inhibited PGF2α and LTB4 in cells and demonstrated IC50 values of 0.19 μM for PGHS-2 and 20 μM for PGHS-1.

INCB 3284 dimesylate is a selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2 (IC50: 3.7 nM). It can be used in the research of acute liver failure.

Masupirdine mesylate (SUVN-502 mesylate) is a selective 5-HT6 receptor antagonist that crosses the blood-brain barrier and is utilized in the study of neurological disorders such as Alzheimer's disease and dementia.

9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.

BL-1020 Mesylate (CYP-1020 Mesylate) is an orally available GABA A receptor agonist and D2 antagonist that decreases dopamine activity and enhances GABAA activity.BL-1020 Mesylate has been used in the study of schizophrenia, Alzheimer's disease, and bi-directional cognitive impairment.

Ono-3307 mesylate is a protease inhibitor with inhibitory effects on a variety of proteases.Ono-3307 mesylate has significant protective effects against liver injury in rats and inhibits the deposition of radiofibrillar proteins in the kidneys and lungs.PF-184298 is a protease inhibitor with potential antioxidant effects in plasma and adipose tissue.PF-184298 can be used in the study of pancreatitis.

Pentamidine dimesylate is an inhibitor of calcium-dependent complex formation with p53 [(Ca)S100B-p53) in malignant melanoma (MM). Pentamidine dimesylate restores p53 tumor suppressor activity in vivo.

Tirilazad mesylate (U 74006F) is a non-glucocorticoid, lipid peroxidation inhibitor with antiviral and neuroprotective activities. It confines intracellular intramembranous foci, attenuates spinal cord injuries induced by trauma, stroke, and ischemia/reperfusion injuries, inhibits toxins in dogs, and is used in the study of neurological disorders.