l 5

L5-DA is a G-quadruplex (G4) ligand that selectively stabilizes G4s, exhibiting significant cytotoxicity to HeLa cells with an IC50 value of 4.3 μM. It stabilizes G4s in HeLa cells, blocking the cell cycle and inducing apoptosis.

L-5-BromoTryptophan (5-BrW) is an analog of the tryptophan (Trp) effector and inhibits the gelation of hemoglobin S.

5-Fluoro-L-tryptophan is a competitive inhibitor of the vesicular glutamate transporter (VGLUT). It holds potential for research related to disorders involving neurotransmitter systems.

Guanine-2'-deoxy-β-L-ribofuranosyl-5'-O-triphosphate (sodium) is an isomer of dGTP and functions as an inhibitor of telomerase, with an inhibition constant (Ki) of 15 μM for the human enzyme.

L-Lysine, mono(2-(((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)thio)propanoate) can be used in related research in the field of life sciences. Its product number is T32817 and CAS number is 61560-15-4.

SJP-L-5 is a inhibitor of HIV-1 infection by blocking viral DNA nuclear entry.

L-5-Methyluridine, an L-configuration of 5-Methyluridine, is an endogenous methylated nucleoside present in human fluids.

5-Hydroxy-L-tryptophan-4,6,7-D3 is L-5-Hydroxytryptophan labeled with 2H. L-5-Hydroxytryptophan (L-5-HTP) is a dietary supplement and a precursor to serotonin, which inhibits the IFN-γ induced PD-L1 expression. It promotes anti-tumor immunity and is used in research on migraine and depression.

Guanine-β-L-ribofuranosyl-5'-O-triphosphate (sodium) is an isomer of iso-guanosine-5'-O-triphosphate.

B-AP15 (NSC-687852)(NSC-687852) is a selective inhibitor of the deubiquitinating enzymes Usp14 and UCHL5 of the 26S proteasome. It blocks the deubiquitinating activity of the 26S proteasome.

Nucleoside Derivatives - L-Nucleosides, Azido-nucleosides, Halo-nucleosides; Scaffolds and Templates

6-Diazo-5-oxo-L-nor-Leucine (DON) is a glutamine antagonist, an irreversible glutaminolysis inhibitor (Ki=6 μM) with antitumor (particularly pancreatic cancer), antibacterial, and antiviral activities.

Fmoc-L-glutamic acid 5-tert-butyl ester (Fmoc-Glu(OtBu)-OH) is a glutamic acid derivative.

H-Glu(OMe)-OH, a glutamate derivative, is used in synthesizing various compounds and is associated with immune and metabolic processes in the body.

CathepsinL-IN-5 (D6-3) is a potent inhibitor of Cathepsin L (CatL) with an IC50 value of 0.27 nM. It effectively blocks the function of CatL and significantly impedes the entry of SARS-CoV-2 pseudovirus into cells by inhibiting the cleavage of the spike protein. CathepsinL-IN-5 is applicable for research on infections.

L-AP5 is a NMDA antagonist.

L-Glutamic-5-14C acid is a bioactive chemical.

L-Lysine, 5'-ester with 3'-azido-3'-deoxythymidine is a bioactive chemical.

Vem-L-Cy5 (compound 3), a Vemurafenib-based BRAF inhibitor conjugated with the near-infrared (NIR) fluorophore cyanine-5 (Cy5), selectively targets the BRAF V600E mutation and inhibits MEK phosphorylation. This compound demonstrates cell permeability and has been shown to inhibit the growth of various cancer cell types [1].

RSV L-protein-IN-5 (Compound E) serves as a potent inhibitor of the Respiratory Syncytial Virus (RSV), with an EC50 value of 0.1 μM. It targets RSV polymerase with an IC50 of 0.66 μM and impedes RSV mRNA synthesis through the inhibition of transcript guanylation. The compound demonstrates moderate cytotoxicity, with a CC50 of 10.7 μM in HEp-2 cells, and effectively reduces viral titers in mouse models of RSV infection [1].

Thymidine-5'-diphosphate-L-rhamnose disodium, isolated from Occhromonas malhamensis [1], is a chemical compound.

HS-(CH2)3CO-L-Ala-D-Ala-L-Ala-NH-CH2-S-(CH2)5-CO-DM is a peptide-cleavable agent-linker conjugate used in antibody-drug conjugates (ADCs), with DM indicating the maytansinoid component [1].

4-Chloro-3-methoxy-5-methylphenyl 6-O-(6-deoxy-β-L-mannopyranosyl)-β-D-glucopyranoside (compound 3), a natural anticancer agent extracted from Lilium regale, exhibits potent inhibitory effects on the proliferation of A549 lung cancer cells and holds promise for applications in cancer research [1].

L-Glutamine-13C5,15N2 is L-Glutamine (T0326L) labeled with 13C and 15N. L-Glutamine (T0326L) (L-Glutamic acid 5-amide) is a non-essential amino acid found abundantly in the human body and plays a role in various metabolic processes. It serves as a carbon source for oxidation in certain cells.