Search Result

Search Results for " induction "

Targets

NOD

268

Compounds

Natural Products

664

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T16159	Muramyl dipeptide	MDP	NOD
	Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide indirectly decreases osteoclast differentiation...		NOD
T2051	SKLB4771	FLT3-IN-1,FLT3-IN-1	FLT
	SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.		FLT
T3147	Pyrrolidinedithiocarbamate ammonium	PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate	NF-κB
	Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction.		NF-κB
T21714	BMS453	BMS 453,BMS-189453	Retinoid Receptor
	BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.		Retinoid Receptor
T27949	LY382884	LY-382884,LY 382884	GluR
	LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade of mossy fibre LTP induction.		GluR
T34076	Piprozolin	W3699,W-3699,W 3699
	Piprozolin (W 3699) is a new type of choleretic acid that shows slight analgesic properties at high doses during chronic experiments.Piprozolin has a slight induction of certain enzymes of the oxidative system.
T11209	EOAI3402143		DUB
	EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis. EOAI3402143 phenocopies the FAS induction and apoptotic sensitization of Usp5 knockdown and fully blocks melanoma tumor growth.		DUB
T13736	Interferon receptor inducer-1		IFNAR
	Interferon receptor inducer-1 Used in the treatment of a disorder in which the induction of interferon is involved. is an interferon (IFN) receptor inducer.		IFNAR
T1535	Sodium 4-phenylbutyrate	Sodium Phenylbutyrate,Buphenyl,TriButyrate	Apoptosis , HDAC , Autophagy
	Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II histone deacetylases (HDACs )resulting in a global increase in gene expression, decreased cellular proliferation, inc...		Apoptosis , HDAC , Autophagy
T27064	CP-312	CP312,Cardioprotectant 312	Reactive Oxygen Species , Autophagy
	CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and targeting the antioxidant response network by inducing HMOX1...		Reactive Oxygen Species , Autophagy
T2445	FG-2216	YM-311,FG2216,FG 2216	HIF/HIF Prolyl-Hydroxylase
	FG-2216 (YM-311) is a potent HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme (IC50: 3.9 uM); orally bioavailable and induced reversible and significant Epo induction in vivo.		HIF/HIF Prolyl-Hydroxylase
T5983	O-Phenanthroline	1,10-Phenanthroline	MMP , Others
	o-Phenanthroline (1,10-Phenanthroline) , a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-Phenanthroline protects mammalian cells from hydrogen peroxide-induced gene m...		MMP , Others
T4615	Balsalazide sodium hydrate	Balsalazide disodium dihydrate,Balsalazide disodium salt dihydrate,Balsalazide disodium	STAT , Interleukin
	Balsalazide sodium hydrate (Balsalazide disodium) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide sodium hydrate is a new 5-aminosalicylic acid (5-ASA) containing prodrug....		STAT , Interleukin
T5521	Bropirimine	U-54461	TLR
	Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.		TLR
T9853	STING activator Compound 53		STING
	STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint cons...		STING
TP2111L	TAT-GluA2 3Y acetate(1404188-93-7 free base)		GluR
	TAT-GluA2 3Y acetate is an inhibitor of AMPA receptor endocytosis.Systemic administration of Tat-GluA2(3Y) during the induction phase of d-amphetamine blocked maintenance of behavioural sensitization and attenuated the m...		GluR
T6891	MK-4101		Apoptosis , Hedgehog/Smoothened , Smo
	MK-4101, an effective inhibitor of the Hedgehog pathway, has anti-tumor activity through the induction of extensive apoptosis and inhibition of proliferation in tumor cells.		Apoptosis , Hedgehog/Smoothened , Smo
T3684	CP21R7	CP21	GSK-3 , PKC
	CP21R7 (CP21) is an effective and specific GSK3β inhibitor. It is used as an activator of stem cells prior to the induction of differentiation of stem cells to smooth muscle and endothelial cells. CP21R7 can be combined ...		GSK-3 , PKC
T8969	API-1	NSC177223	Akt
	API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .		Akt
T21017	5'-Amino-5'-deoxyadenosine	5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo	Apoptosis , Adenosine Receptor
	5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer effects.The anticancer mechanism of 5'-Amino-5'-deoxyadenosine ...		Apoptosis , Adenosine Receptor
T1608	ADH-1 trifluoroacetate	Exherin trifluoroacetate	Dehydrogenase
	ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-c...		Dehydrogenase
T1002	Etodolac	Ultradol,AY-24236,Etodolic acid,Lodine	Retinoid Receptor , COX
	Etodolac (AY-24236) inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. Etodolac is a pyranocarboxylic ...		Retinoid Receptor , COX
T3351	Onatasertib	CC223,CC 223,CC-223	Apoptosis , c-Fms , DNA-PK , FLT , PI3K , mTOR
	Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity. Onatasertib inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor ce...		Apoptosis , c-Fms , DNA-PK , FLT , PI3K , mTOR
T10352	APTO-253	LOR-253,LT-253	Apoptosis , c-Myc , KLF
	APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the K...		Apoptosis , c-Myc , KLF
T60472	GSK-3β inhibitor 12		GSK-3
	GSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM GSK-3β activity and 37.11% of 50 μM GSK-3β activity.GSK-3β inhibitor 12 can be used for the study of Parkinson's in the pre...		GSK-3
T41362	EM-12	Phthalimidinoglutarimide,2-(2,6-Dioxopiperidin-3-yl)phthalimidine	Others
	2-(2,6-Dioxopiperidin-3-yl)phthalimidine (EM-12 (2-(2,6-Dioxopiperidin-3-yl)phthalimidine)) is a teratogenic Thalidomide analogue that is more active than Thalidomide and is much more stable for hydrolysis. 2-(2,6-Dioxop...		Others
T6831	Etretinate	Retinoid,Tegison,Etretinato,Ethyl etrinoate,Ro 10-9359	Apoptosis , Others
	Etretinate (Ro 10-9359) is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of c...		Apoptosis , Others
T35528L	TD52 dihydrochloride	TD52 dihydrochloride(1798328-24-1 Free base),TD52 2HCl	Others
	TD52 dihydrochloride (TD52 2HCl), a derivative of Erlotinib, is a potent and orally active inhibitor of protein phosphatase 2A (CIP2A). It exhibits strong anti-cancer properties by regulating the CIP2A/PP2A/p-Akt signali...		Others
T3124	Carbendazim	Bavistin,Carbendazole,Mercarzole	Antifungal
	Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspec...		Antifungal
T1849	Momelotinib	CYT11387,CYT387,LM-1149	Apoptosis , JAK , Autophagy
	Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhib...		Apoptosis , JAK , Autophagy
T1625	Lomefloxacin hydrochloride	Lomefloxacin HCl,Okacyn,Maxaquin	Topoisomerase , Antibacterial , Antibiotic
	Lomefloxacin hydrochloride (Okacyn) inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during...		Topoisomerase , Antibacterial , Antibiotic
T40795	BNTA		Reactive Oxygen Species
	BNTA is a potent extracellular matrix (ECM) modulator. In a rat model of arthritis, BNTA modulates arthritis by promoting the synthesis of cartilage structural molecules on chondrocytes through the induction of superoxid...		Reactive Oxygen Species
T0977	Medrysone	Gimeracil,6α-Methyl-11β-hydroxyprogesterone	Glucocorticoid Receptor , Others
	Medrysone (6α-Methyl-11β-hydroxyprogesterone) is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with specific intracellular ...		Glucocorticoid Receptor , Others
T6017	Linsitinib	OSI-906	IGF-1R
	OSI-906 (Linsitinib (OSI-906)) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R, whic...		IGF-1R
TNU0630	2'-O-Methyl-5-iodouridine	5-Iodo-2'-O-methyluridine
	2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of antitumor activity. The anticancer mechani...
T19965	Dacomitinib hydrate	PF 299804,PF00299804,PF 00299804,PF-00299804,PF299804,PF-299804	EGFR
	Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of tyrosine kinases. Dacomitinib specifically and irreversibly binds...		EGFR
T3637	Pifithrin-β hydrobromide	Cyclic PFT-α,PFT-β,Cyclic Pifithrin-α hydrobromide,Pifithrin-β,PFT β (hydrobromide)	Ferroptosis , p53
	Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorder...		Ferroptosis , p53
T3352	XL413		cholecystokinin , Casein Kinase , Pim , CDK
	XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. XL-413 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA ...		cholecystokinin , Casein Kinase , Pim , CDK
T3617	Ivosidenib	AG-120	Dehydrogenase , Isocitrate Dehydrogenase (IDH)
	Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Ivosidenib specifically inhibits a mutated form of IDH1 in the cytoplasm, which inhi...		Dehydrogenase , Isocitrate Dehydrogenase (IDH)
T4062	CAY10602		Sirtuin
	CAY10602 is a SIRT1 activator. CAY10602 was derived from high throughput screening for compounds that increase SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays show that CAY10602 dose-depende...		Sirtuin
T33701	NM-3	NM-3,isocoumarin,NM 3,Isocoumarin NM-3,NM3	Apoptosis , Reactive Oxygen Species
	NM-3 is an orally available anti-angiogenic inhibitor with anti-tumour activity.NM-3 is used as a radiation modulator in vitro and in vivo.NM-3 inhibits vascular endothelial growth factor (VEGF), thereby inhibiting the p...		Apoptosis , Reactive Oxygen Species
T3661	Citarinostat	ACY241,HDAC-IN-2	HDAC
	ACY-241, also known as Citarinostat (ACY241), is a potent, selective and orally available histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity. Upon oral administration, ACY-241 inhibits the activ...		HDAC
T3716	Rolapitant	SCH619734	Neurokinin receptor
	Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ...		Neurokinin receptor
T16328	Nitroaspirin	NCX 4016	Apoptosis , COX
	Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin induces significant induction of cell cycle arrest and apoptosis...		Apoptosis , COX
T0153	Oltipraz	NSC 347901,RP 35972	HIF/HIF Prolyl-Hydroxylase , HIV Protease , Reverse Transcriptase , Nrf2 , HIF
	Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as glutathione S transferase (GST) and NAD(P)H: quin...
T3157	COH29	RNR Inhibitor COH29	DNA/RNA Synthesis
	COH29 (RNR Inhibitor COH29) is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase (RNR), with potential antineoplastic activity. Upon oral administration, the RNR i...		DNA/RNA Synthesis
T36083	DS-7423		PI3K , mTOR
	DS-7423 is a dual PI3K and mTOR inhibitor, with IC50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR, respectively. DS-7423 possesses anti-tumor activity[1][2]. DS-7423 increases TP53 expression, the level of p-TP53 on Ser...		PI3K , mTOR
T36674	DMU-212		Apoptosis , ERK
	DMU-212 is a methylated derivative of Resveratrol , with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2...		Apoptosis , ERK
T25507	HP 228	HP-228,Ac-Nle-gln-his-D-phe-arg-D-trp-gly-NH2,HP228
	HP 228 is a heptapeptide by inhibits the induction of nitric oxide synthase.
T25275	Crambene	NSC 321802,NSC-321802,NSC321802
	Crambene results in the induction of apoptosis by protects mice against acute pancreatitis via anti-inflammatory pathways.

Compounds

Synonym: FLT3-IN-1,FLT3-IN-1

Target: FLT

Pyrrolidinedithiocarbamate ammonium

T3147

Synonym: PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate

Target: NF-κB

BMS453

T21714

Synonym: BMS 453,BMS-189453

Target: Retinoid Receptor

LY382884

T27949

Synonym: LY-382884,LY 382884

Target: GluR

Piprozolin

T34076

Synonym: W3699,W-3699,W 3699

Interferon receptor inducer-1

T13736

Synonym:

Target: IFNAR

Sodium 4-phenylbutyrate

T1535

Synonym: Sodium Phenylbutyrate,Buphenyl,TriButyrate

Target: Apoptosis, HDAC, Autophagy

CP-312

T27064

Synonym: CP312,Cardioprotectant 312

Target: Reactive Oxygen Species, Autophagy

FG-2216

T2445

Synonym: YM-311,FG2216,FG 2216

Target: HIF/HIF Prolyl-Hydroxylase

o-Phenanthroline

T5983

Synonym: 1,10-Phenanthroline

Target: MMP, Others

Balsalazide sodium hydrate

T4615

Synonym: Balsalazide disodium dihydrate,Balsalazide disodium salt dihydrate,Balsalazide disodium

Target: STAT, Interleukin

STING activator Compound 53

T9853

Synonym:

Target: STING

TAT-GluA2 3Y acetate(1404188-93-7 free base)

Target: Apoptosis, Hedgehog/Smoothened, Smo

5'-Amino-5'-deoxyadenosine

T21017

Synonym: 5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo

Target: Apoptosis, Adenosine Receptor

ADH-1 trifluoroacetate

T1608

Synonym: Exherin trifluoroacetate

Target: Dehydrogenase

Etodolac

T1002

Synonym: Ultradol,AY-24236,Etodolic acid,Lodine

Target: Retinoid Receptor, COX

Onatasertib

T3351

Synonym: CC223,CC 223,CC-223

Target: Apoptosis, c-Fms, DNA-PK, FLT, PI3K, mTOR

APTO-253

T10352

Synonym: LOR-253,LT-253

Target: Apoptosis, c-Myc, KLF

Synonym: Phthalimidinoglutarimide,2-(2,6-Dioxopiperidin-3-yl)phthalimidine

Target: Others

Etretinate

T6831

Synonym: Retinoid,Tegison,Etretinato,Ethyl etrinoate,Ro 10-9359

Target: Apoptosis, Others

TD52 dihydrochloride

T35528L

Synonym: TD52 dihydrochloride(1798328-24-1 Free base),TD52 2HCl

Target: Others

Carbendazim

T3124

Synonym: Bavistin,Carbendazole,Mercarzole

Target: Antifungal

Momelotinib

T1849

Synonym: CYT11387,CYT387,LM-1149

Target: Apoptosis, JAK, Autophagy

Lomefloxacin hydrochloride

T1625

Synonym: Lomefloxacin HCl,Okacyn,Maxaquin

Target: Topoisomerase, Antibacterial, Antibiotic

BNTA

T40795

Synonym:

Target: Reactive Oxygen Species

Medrysone

T0977

Synonym: Gimeracil,6α-Methyl-11β-hydroxyprogesterone

Target: Glucocorticoid Receptor, Others

2'-O-Methyl-5-iodouridine

TNU0630

Synonym: 5-Iodo-2'-O-methyluridine

Target:

Dacomitinib hydrate

T19965

Synonym: PF 299804,PF00299804,PF 00299804,PF-00299804,PF299804,PF-299804

Target: EGFR

Pifithrin-β hydrobromide

T3637

Synonym: Cyclic PFT-α,PFT-β,Cyclic Pifithrin-α hydrobromide,Pifithrin-β,PFT β (hydrobromide)

Target: Ferroptosis, p53

XL413

T3352

Synonym:

Target: cholecystokinin, Casein Kinase, Pim, CDK

Ivosidenib

T3617

Synonym: AG-120

Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)

Synonym: NM-3,isocoumarin,NM 3,Isocoumarin NM-3,NM3

Target: Apoptosis, Reactive Oxygen Species

Citarinostat

T3661

Synonym: ACY241,HDAC-IN-2

Target: Neurokinin receptor

Nitroaspirin

T16328

Synonym: NCX 4016

Target: Apoptosis, COX

Oltipraz

T0153

Synonym: NSC 347901,RP 35972

Target: HIF/HIF Prolyl-Hydroxylase, HIV Protease, Reverse Transcriptase, Nrf2, HIF

COH29

T3157

Synonym: RNR Inhibitor COH29

Target: DNA/RNA Synthesis

Target: Apoptosis, ERK

HP 228

T25507

Synonym: HP-228,Ac-Nle-gln-his-D-phe-arg-D-trp-gly-NH2,HP228

Target:

Crambene

T25275

Synonym: NSC 321802,NSC-321802,NSC321802

Target:

Cat No.	Product Name	Synonyms	Targets
TN1455	Bryodulcosigenin		Immunology/Inflammation related
	Bryodulcosigenin has anti-inflammatory effect, it shows potent inhibitory effects on EBV-EA induction.		Immunology/Inflammation related
T8417	Pheanthine		Others
	Pheanthine is an extract of the fruit of Gyrocarpus jacquinii and shows induction of C/EBPα activity.		Others
TQ0191	Dihydromethysticin	(+)-Dihydromethysticin	P450
	Dihydromethysticin ((+)-Dihydromethysticin) is a kavalactone found in Piper methysticum. It has marked activity on the induction of CYP3A23.		P450
TN3016	4',6,7-Trimethoxyisoflavone		MMP
	4',6,7-Trimethoxyisoflavone promotes wound healing through NOX2 induction, which leads to collective migration and MMP activation.		MMP
T14011	2-Arachidonoylglycerol		Cannabinoid Receptor , Endogenous Metabolite
	In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand		Cannabinoid Receptor , Endogenous Metabolite
T6S0234	Toosendanin		Others
	1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocytic leukemia HL-6 cells. 3. Toosendanin i...		Others
T3918	Ginsenoside Rb3	Gypenoside IV	NF-κB , COX , NO Synthase
	Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits the induction of COX-2 and iNOS mRNA.		NF-κB , COX , NO Synthase
TMS0484	Episyringaresinol 4'-O-β-D-glncopyranoside	(-)-Syringaresinol 4-O-β-D-glucopyranosi	Others
	Episyringaresinol 4'-O-β-D-glncopyranoside ((-)-Syringaresinol 4-O-β-D-glucopyranosi) inhibits the proliferation of human promyelocytic HL-6 cells through G(1) arrest and induction of apoptosis, may be a potential chemot...		Others
T5S0734	Desmethoxyyangonin	Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain	Others , Monoamine Oxidase
	1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydr...		Others , Monoamine Oxidase
T5S1607	Morusin	Mulberrochromene	NF-κB , Antibacterial , STAT
	1. Morusin (Mulberrochromene) possesses antitumor effects of cell lines including HT-29, A549, MCF-7, and MDA-MB-231, through suppressing STAT3 and NFκB attenuation mediated apoptosis induction. 2. Morusin possesses anti...		NF-κB , Antibacterial , STAT
TN1461	(-)-Butin	Butin	Akt , PI3K , Nrf2
	(-)-Butin (Butin) has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SO...		Akt , PI3K , Nrf2
TJS0487	(-)-Syringaresinol	DL-Syringaresinol,Lirioresinol b	Others
	(-)-Syringaresinol (DL-Syringaresinol) is derived from the stems of Annona Montana. (-)-Syringaresinol inhibits the proliferation of human promyelocytic HL-60 cells through G1 arrest and induction of apoptosis and posses...		Others
T2S0886	Terrestrosin D		Apoptosis , Others
	Terrestrosin D can induce apoptotic cell death and inhibit angiogenesis in xenograft tumor cells, cell cycle arrest and induction of apoptosis in cancer cells and endothelial cells might be plausible mechanisms of action...		Apoptosis , Others
T2S1778	DL-Goitrin	Goitrin	Others
	DL-Goitrin is a potent antithyroid compound found naturally in crucifers. DL-Goitrin is responsible for the induction of glutathione S-transferases. DL-Goitrin is a moderate inhibitor of purified bovine adrenal dopamine ...		Others
T5S1285	(+)-(3R,8S)-Falcarindiol	Falcarindiol	Others
	1. (+)-(3R,8S)-Falcarindiol is a potential new anticancer agent that exerts its activity through inducing ER stress and apoptosis. 2. Falcarindiol induces immunosuppressive effects in vitro and in vivo and might be a nov...		Others
TN1661	Ganoderic acid C2		Reductase , Histamine Receptor , Immunology/Inflammation related
	Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen.
T3395	Timosaponin AIII	Filiferin B,AneMarsaponin A3,Timosaponin A3	AChE , mTOR
	Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC...		AChE , mTOR
TN6972	Methyl pentadecanoate		Others
	Methyl pentadecanoate is a natural product.		Others
T6S1885	Benzoylmesaconine	Mesaconine 14-benzoate	Others
	Benzoylmesaconine (Mesaconine 14-benzoate) is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis. Benzoylmesconine has analgesic activi...		Others
T3S1227	Aristolactam I	Aristolactam,Aristololactam I,Aristololactum	Apoptosis , Caspase
	1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF...		Apoptosis , Caspase
T4916	D-Glucaric acid potassium	D-Saccharic acid potassium salt,Glucosaccharic acid,Glucaric Acid	Others , Endogenous Metabolite
	D-Glucaric acid potassium (D-Saccharic acid potassium salt) is a compound formed from oxidizing sugars, which can be used to test for the presence of hepatic enzyme induction. Studies indicate that D-glucuronolactone deh...		Others , Endogenous Metabolite
TL0007	Bisdemethoxycurcumin	Curcumin III,Didemethoxycurcumin	Epigenetic Reader Domain , Wnt/beta-catenin
	Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by mac...		Epigenetic Reader Domain , Wnt/beta-catenin
TN2091	Polygalacin D		Apoptosis , IAP
	Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxi...		Apoptosis , IAP
T3S1967	(S)-Indoximod	N-ME-Tryptophan,Abrine,L-Abrine	Others , Indoleamine 2,3-Dioxygenase (IDO)
	(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L...		Others , Indoleamine 2,3-Dioxygenase (IDO)
TN1804	Isosilybin A		Apoptosis , Tyrosinase , PPAR , ABC
	Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) of tyrosinase. Isosilybin A shows anti-angio...		Apoptosis , Tyrosinase , PPAR , ABC
T0034	Cortisone acetate	Cortisone 21-acetate,NSC 49420	Glucocorticoid Receptor , Endogenous Metabolite
	Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate (NSC-49420) d...		Glucocorticoid Receptor , Endogenous Metabolite
T3S0081	Oxypeucedanin	(+-)-Oxypeucedanin,Oxypeucadanin	Potassium Channel
	1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocke...		Potassium Channel
TWS2045	Bruceine D		Apoptosis , Antiviral , Gamma-secretase , Parasite
	1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW...		Apoptosis , Antiviral , Gamma-secretase , Parasite
T6S1027	Tussilagone		Others
	1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human co...		Others
T6S2391	L-Chicoric Acid	(-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid	Others , HIV Protease
	L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ...		Others , HIV Protease
T4S1615	Sanggenon C	Sanggenone C	NF-κB
	1. Sanggenon C (Sanggenone C) inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. 2. Sanggenon C and O inhibited NO pro...		NF-κB
TN1724	Harmalol hydrochloride	Harmidol hydrochloride	P450 , Antioxidant
	Harmalol hydrochloride (Harmidol hydrochloride) is a β-carboline alkaloid that can be extracted from the seeds of Peganum harmala L. Harmalol hydrochloride is the major metabolite of Harmaline and significantly inhibits ...		P450 , Antioxidant
T4S2126	Ginkgetin		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
	1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
T6429	Caffeic Acid Phenethyl Ester	Phenylethyl Caffeate,CAPE	Apoptosis , NF-κB
	Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective...		Apoptosis , NF-κB
T3229	Cytochalasin D		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
T3877	Esculentoside A		NF-κB , COX
	Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmun...		NF-κB , COX
T6S0525	Farrerol		ERK , p38 MAPK , Akt
	1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3....		ERK , p38 MAPK , Akt
T2S2264	Linalool	Linalol,(±)-Linalool,Phantol	Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR
	1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th...
TN1163	2'-Hydroxychalcone		Others
	2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxyc...		Others
T5S2343	Acetylshikonin	Acetyl shikonin	Others , P450 , AChE
	1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang...		Others , P450 , AChE
T3S0027	Picropodophyllotoxin	AXL 1717,Picropodophyllin	IGF-1R
	Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...		IGF-1R
TMA1004	Lucidenic acid F		p38 MAPK , JNK
	Lucidenic acid F as a modulator of JNK and p38, it shows potent inhibitory effects on EBV-EA induction.		p38 MAPK , JNK
T21261	Phaseolin
	Phaseolin, a protein from red kidney bean (Phaseolus vulgaris L.), plays a pivotal role in hypersensitivity induction.
TN4778	Physalin H		gp120/CD4 , Antifection , Autophagy
	Physalin H is an Hh signaling inhibitor blocks GLI1-DNA-complex formation, it also strong quinone reductase induction activity with IR (Induction ratio, QR induction activity) value of 3.74±0.02. Physalin H shows immunos...		gp120/CD4 , Antifection , Autophagy
TL0018	Lobelin		AChR , Antifection
	Inhalation challenge with capsaicin and rapid intravenous injection of Lobelin and alinamin indicated that peripheral c-fiber receptors were involved in the induction of coughing.		AChR , Antifection
TN5575	Coronarin D methyl ether
	Coronarin D methyl ether has inhibitory effects on the increase in vascular permeability, nitric oxide production, and inducible nitric oxide synthase induction.
TN3937	Ent-16alpha,17-Dihydroxyatisan-3-one		P-gp
	ent-16alpha,17-Dihydroxyatisan-3-one and ent-16alpha,17-dihydroxykauran-3-one have apoptosis induction activities on L5178 human MDR1 gene-transfected mouse lymphoma cells.		P-gp
TN2116	Pteropodine		BCL , Calcium Channel , 5-HT Receptor
	Pteropodine acts as a positive modulator of muscarinic M(1) and 5-HT(2) receptors. Pteropodine shows antigenotoxic, antioxidant and lymphocyte induction effects, it also shows strong apoptotic effect on acute leukaemic l...		BCL , Calcium Channel , 5-HT Receptor
TN2076	Pinobanksin		Others
	Pinobanksin and some of its ester derivatives from Sonoran propolis have apoptotic induction in a B-cell lymphoma cell line.		Others
TN2400	Alpha-Terthienylmethanol		Others
	Alpha-terthienylmethanol possesses potent cytotoxic activity against human endometrial cancer cells; it inhibits growth mediated by the induction of apoptosis, as shown by the accumulation of sub-G1 and apoptotic cells.		Others
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Natural Products

Bryodulcosigenin

TN1455

Synonym:

Target: Immunology/Inflammation related

Synonym: (+)-Dihydromethysticin

Target: P450

4',6,7-Trimethoxyisoflavone

TN3016

Synonym:

Target: MMP

2-Arachidonoylglycerol

T14011

Synonym:

Target: Cannabinoid Receptor, Endogenous Metabolite

Synonym: Gypenoside IV

Target: NF-κB, COX, NO Synthase

Episyringaresinol 4'-O-β-D-glncopyranoside

TMS0484

Synonym: (-)-Syringaresinol 4-O-β-D-glucopyranosi

Target: Others

Desmethoxyyangonin

T5S0734

Synonym: Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain

Target: Others, Monoamine Oxidase

Morusin

T5S1607

Synonym: Mulberrochromene

Target: NF-κB, Antibacterial, STAT

(-)-Butin

TN1461

Synonym: Butin

Target: Akt, PI3K, Nrf2

(-)-Syringaresinol

TJS0487

Synonym: DL-Syringaresinol,Lirioresinol b

Target: Apoptosis, Others

(+)-(3R,8S)-Falcarindiol

T5S1285

Synonym: Falcarindiol

Target: Reductase, Histamine Receptor, Immunology/Inflammation related

Timosaponin AIII

T3395

Synonym: Filiferin B,AneMarsaponin A3,Timosaponin A3

Target: AChE, mTOR

Methyl pentadecanoate

Synonym: Mesaconine 14-benzoate

Target: Others

Aristolactam I

T3S1227

Synonym: Aristolactam,Aristololactam I,Aristololactum

Target: Apoptosis, Caspase

D-Glucaric acid potassium

T4916

Synonym: D-Saccharic acid potassium salt,Glucosaccharic acid,Glucaric Acid

Target: Others, Endogenous Metabolite

Bisdemethoxycurcumin

TL0007

Synonym: Curcumin III,Didemethoxycurcumin

Target: Epigenetic Reader Domain, Wnt/beta-catenin

Polygalacin D

TN2091

Synonym:

Target: Apoptosis, IAP

(S)-Indoximod

T3S1967

Synonym: N-ME-Tryptophan,Abrine,L-Abrine

Target: Others, Indoleamine 2,3-Dioxygenase (IDO)

Isosilybin A

TN1804

Synonym:

Target: Apoptosis, Tyrosinase, PPAR, ABC

Cortisone acetate

T0034

Synonym: Cortisone 21-acetate,NSC 49420

Target: Glucocorticoid Receptor, Endogenous Metabolite

Oxypeucedanin

T3S0081

Synonym: (+-)-Oxypeucedanin,Oxypeucadanin

Target: Potassium Channel

Bruceine D

TWS2045

Synonym:

Target: Apoptosis, Antiviral, Gamma-secretase, Parasite

Synonym: (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid

Target: Others, HIV Protease

Sanggenon C

T4S1615

Synonym: Sanggenone C

Target: NF-κB

Harmalol hydrochloride

TN1724

Synonym: Harmidol hydrochloride

Target: P450, Antioxidant

Ginkgetin

T4S2126

Synonym:

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

Caffeic Acid Phenethyl Ester

T6429

Synonym: Phenylethyl Caffeate,CAPE

Target: Apoptosis, NF-κB

Cytochalasin D

T3229

Synonym:

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

Target: ERK, p38 MAPK, Akt

Linalool

T2S2264

Synonym: Linalol,(±)-Linalool,Phantol

Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR

Synonym: Acetyl shikonin

Target: Others, P450, AChE

Picropodophyllotoxin

T3S0027

Synonym: AXL 1717,Picropodophyllin

Target: p38 MAPK, JNK

Target: gp120/CD4, Antifection, Autophagy

Lobelin

TL0018

Synonym:

Target: AChR, Antifection

Coronarin D methyl ether

TN5575

Synonym:

Target:

ent-16alpha,17-Dihydroxyatisan-3-one

Target: BCL, Calcium Channel, 5-HT Receptor

alpha-Terthienylmethanol

TN2400

Synonym:

Target: Others

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02594	Noggin/NOG Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPY-05202	Noggin/NOG Protein, Human, Recombinant	Human	HEK293
	Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPY-00890	Noggin/NOG Protein, Human, Recombinant (hFc)	Human	HEK293
	Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPY-03956	Fas Ligand Protein, Human, Recombinant (His)	Human	Yeast
	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su...
TMPY-03104	FGF-17 Protein, Human, Recombinant	Human	E. coli
	FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including ...
TMPY-06842	BMP-4 Protein, Human, Recombinant (E399D)	Human	E. coli
	BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPY-00369	LY6D Protein, Human, Recombinant (mFc)	Human	HEK293
	LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of...
TMPY-05053	ANGPTL2 Protein, Human, Recombinant (His)	Human	HEK293
	The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-04793	IL-35 Protein, Human, Recombinant (Flag & His)	Human	HEK293
	IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ...
TMPY-02157	GST Protein, Schistosoma japonicum, Recombinant	Schistosoma japonicum	Baculovirus-Insect Cells
	Genetic engineers have used glutathione S-transferase to create the GST gene fusion system. This system is used to purify and detect proteins of interest. In a GST gene fusion system, the GST sequence is incorporated int...
TMPY-01941	CD28 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and ...
TMPH-00005	YAP1 Protein, Human, Recombinant (Isoform 9, His)	Human	Yeast

TMPY-05354	CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and ...
TMPY-06021	CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His)	Human,Cynomolgus,Rhesus	HEK293
	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and ...
TMPY-00413	TGF beta 2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPJ-00865	VEGF121 Protein, Human, Recombinant (His)	Human	Human Cells
	Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD...
TMPY-03577	Pleiotrophin/PTN Protein, Mouse, Recombinant	Mouse	Baculovirus-Insect Cells
	HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, ...
TMPY-01894	SIGIRR Protein, Human, Recombinant (His)	Human	HEK293
	Single Ig IL-1-related receptor (SIGIRR) or TIR8 is a member of Toll-like receptor-interleukin 1 receptor signaling (TLR-IL-1R) receptor superfamily. Although SIGIRR/TIR8 shows the typical conserved motifs that character...
TMPJ-00375	HGF Protein, Human, Recombinant (His)	Human	Human Cells
	HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propepti...
TMPY-02087	IL-24 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-24 (IL-24) also known as Melanoma differentiation-associated gene 7 protein (MDA-7) is a member of the IL10 family of cytokines. IL-24/MDA-7/IL24 can induce apoptosis selectively in various cancer cells. Over...
TMPY-01694	Clusterin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-02473	ICOS Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPY-05156	ICOS Protein, Human, Recombinant (rFc)	Human	HEK293
	Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPY-02813	ErbB4 Protein, Human, Rhesus, Recombinant (His)	Human,Rhesus	HEK293
	ERBB4 is a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. ERBB4 is ...
TMPY-01691	Clusterin Protein, Human, Recombinant (CLU34, His)	Human	HEK293
	Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-03802	IL-17F Protein, Human, Recombinant (aa 31-163)	Human	E. coli
	Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a...
TMPY-00856	TCCR Protein, Human, Recombinant (hFc)	Human	HEK293
	The interleukin-27 receptor is a type I cytokine receptor for interleukin-27. It is a heterodimer composed of the interleukin 27 receptor, alpha subunit, and glycoprotein 130. WSX-1/IL-27R, a class I cytokine receptor th...
TMPY-06034	FGFR1 Protein, Human, Recombinant (beta (IIIb), His)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01011	FGFR1 Protein, Human, Recombinant (His)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-00835	IGFBP-3 Protein, Human, Recombinant (His)	Human	HEK293
	The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory...
TMPY-06036	FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)	Human	HEK293
	FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-05593	IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Interleukin-1 receptor accessory protein (IL-1RAcP) also known as Interleukin-1 receptor member 3 (IL-1R3) is a cytokine receptor that binds interleukin 1. The IL-1 receptor accessory protein (IL1RAP) is a transmembrane ...
TMPY-04580	IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Interleukin-1 receptor accessory protein (IL-1RAcP) also known as Interleukin-1 receptor member 3 (IL-1R3) is a cytokine receptor that binds interleukin 1. The IL-1 receptor accessory protein (IL1RAP) is a transmembrane ...
TMPY-05840	IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Interleukin-1 receptor accessory protein (IL-1RAcP) also known as Interleukin-1 receptor member 3 (IL-1R3) is a cytokine receptor that binds interleukin 1. The IL-1 receptor accessory protein (IL1RAP) is a transmembrane ...
TMPY-01403	VNN1 Protein, Human, Recombinant (His)	Human	HEK293
	Pantetheinase, also known as Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, and VNN1, is a cell membrane protein which belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 contains one...
TMPY-04483	IRAK4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-06013	Human coronavirus (HCoV-OC43) Spike S2 Protein (His)	HCoV-OC43	Baculovirus-Insect Cells
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-05677	Human coronavirus (HCoV-OC43) Spike Protein (S1+S2 ECD, His)	HCoV-OC43	Baculovirus-Insect Cells
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-05679	SARS-CoV-2 Spike RBD Protein (hFc)	SARS-CoV-2	HEK293
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-05750	Human coronavirus (HCoV-OC43) Spike S1 Protein (His)	HCoV-OC43	HEK293
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-05670	Human coronavirus (HCoV-NL63) Spike S1 Protein (His)	HCoV-NL63	HEK293
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-05674	Human coronavirus (HCoV-NL63) Spike Protein (S1+S2 ECD, His)	HCoV-NL63	Baculovirus-Insect Cells
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-05675	Human coronavirus (HCoV-229E) Spike Protein (S1+S2 ECD, His)	HCoV-229E	Baculovirus-Insect Cells
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-03574	MERS-CoV Spike/S1 Protein (aa 1-725, His)	MERS-CoV	HEK293
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-01621	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-05227	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-05671	Human coronavirus (HCoV-229E) Spike S1 Protein (His)	HCoV-229E	HEK293
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-03512	MERS-CoV Spike/S2 Protein (aa 726-1296, His)	MERS-CoV	Baculovirus-Insect Cells
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-05676	Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) Spike Protein (S1+S2 ECD, His)	HCoV-HKU1	Baculovirus-Insect Cells
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
TMPY-02429	Human coronavirus HKU1 (isolate N1) (HCoV-HKU1) Spike S1 Protein (His)	HCoV-HKU1	HEK293
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...
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Noggin/NOG Protein, Mouse, Recombinant (hFc)

TMPY-02594

Species: Mouse

Expression System: HEK293

Noggin/NOG Protein, Human, Recombinant

TMPY-05202

Species: Human

Expression System: HEK293

Noggin/NOG Protein, Human, Recombinant (hFc)

TMPY-00890

Species: Human

Expression System: HEK293

Fas Ligand Protein, Human, Recombinant (His)

TMPY-03956

Species: Human

Expression System: Yeast

FGF-17 Protein, Human, Recombinant

TMPY-03104

Species: Human

Expression System: E. coli

BMP-4 Protein, Human, Recombinant (E399D)

TMPY-06842

Species: Human

Expression System: E. coli

LY6D Protein, Human, Recombinant (mFc)

TMPY-00369

Species: Human

Expression System: HEK293

ANGPTL2 Protein, Human, Recombinant (His)

TMPY-05053

Species: Human

Expression System: HEK293

IL-35 Protein, Human, Recombinant (Flag & His)

TMPY-04793

Species: Human

Expression System: HEK293

GST Protein, Schistosoma japonicum, Recombinant

TMPY-02157

Species: Schistosoma japonicum

Expression System: Baculovirus-Insect Cells

CD28 Protein, Human, Recombinant (hFc)

TMPY-01941

Species: Human

Expression System: HEK293

YAP1 Protein, Human, Recombinant (Isoform 9, His)

TMPH-00005

Species: Human

Expression System: Yeast

CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPY-05354

Species: Human

Expression System: HEK293

CD28 Protein, Human, Cynomolgus, Rhesus, Recombinant (His)

TMPY-06021

Species: Human,Cynomolgus,Rhesus

Expression System: HEK293

TGF beta 2 Protein, Mouse, Recombinant (His)

TMPY-00413

Species: Mouse

Expression System: HEK293

VEGF121 Protein, Human, Recombinant (His)

TMPJ-00865

Species: Human

Expression System: Human Cells

Pleiotrophin/PTN Protein, Mouse, Recombinant

TMPY-03577

Species: Mouse

Expression System: Baculovirus-Insect Cells

SIGIRR Protein, Human, Recombinant (His)

TMPY-01894

Species: Human

Expression System: HEK293

HGF Protein, Human, Recombinant (His)

TMPJ-00375

Species: Human

Expression System: Human Cells

IL-24 Protein, Human, Recombinant (His)

TMPY-02087

Species: Human

Expression System: HEK293

Clusterin Protein, Mouse, Recombinant (His)

TMPY-01694

Species: Mouse

Expression System: HEK293

ICOS Protein, Mouse, Recombinant (hFc)

TMPY-02473

Species: Mouse

Expression System: HEK293

ICOS Protein, Human, Recombinant (rFc)

TMPY-05156

Species: Human

Expression System: HEK293

ErbB4 Protein, Human, Rhesus, Recombinant (His)

TMPY-02813

Species: Human,Rhesus

Expression System: HEK293

Clusterin Protein, Human, Recombinant (CLU34, His)

TMPY-01691

Species: Human

Expression System: HEK293

IL-17F Protein, Human, Recombinant (aa 31-163)

TMPY-03802

Species: Human

Expression System: E. coli

TCCR Protein, Human, Recombinant (hFc)

TMPY-00856

Species: Human

Expression System: HEK293

FGFR1 Protein, Human, Recombinant (beta (IIIb), His)

TMPY-06034

Species: Human

Expression System: HEK293

FGFR1 Protein, Human, Recombinant (His)

TMPY-01011

Species: Human

Expression System: HEK293

IGFBP-3 Protein, Human, Recombinant (His)

TMPY-00835

Species: Human

Expression System: HEK293

FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)

TMPY-06036

Species: Human

Expression System: HEK293

IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-05593

Species: Human

Expression System: HEK293

IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His)

TMPY-04580

Species: Mouse

Expression System: HEK293

IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)

TMPY-05840

Species: Cynomolgus

Expression System: HEK293

VNN1 Protein, Human, Recombinant (His)

TMPY-01403

Species: Human

Expression System: HEK293

IRAK4 Protein, Human, Recombinant (His)

TMPY-04483

Species: Human

Expression System: Baculovirus-Insect Cells

Human coronavirus (HCoV-OC43) Spike S2 Protein (His)

TMPY-06013

Species: HCoV-OC43

Expression System: Baculovirus-Insect Cells

Human coronavirus (HCoV-OC43) Spike Protein (S1+S2 ECD, His)

TMPY-05677

Species: HCoV-OC43

Expression System: Baculovirus-Insect Cells

SARS-CoV-2 Spike RBD Protein (hFc)

TMPY-05679

Species: SARS-CoV-2

Expression System: HEK293

Human coronavirus (HCoV-OC43) Spike S1 Protein (His)

TMPY-05750

Species: HCoV-OC43

Expression System: HEK293

Human coronavirus (HCoV-NL63) Spike S1 Protein (His)

TMPY-05670

Species: HCoV-NL63

Expression System: HEK293

Human coronavirus (HCoV-NL63) Spike Protein (S1+S2 ECD, His)

TMPY-05674

Species: HCoV-NL63

Expression System: Baculovirus-Insect Cells

Human coronavirus (HCoV-229E) Spike Protein (S1+S2 ECD, His)

TMPY-05675

Species: HCoV-229E

Expression System: Baculovirus-Insect Cells

MERS-CoV Spike/S1 Protein (aa 1-725, His)

TMPY-03574

Species: MERS-CoV

Expression System: HEK293

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)

TMPY-01621

Species: Human

Expression System: HEK293

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated

TMPY-05227

Species: Human

Expression System: HEK293

Human coronavirus (HCoV-229E) Spike S1 Protein (His)

TMPY-05671

Species: HCoV-229E

Expression System: HEK293

MERS-CoV Spike/S2 Protein (aa 726-1296, His)

TMPY-03512

Species: MERS-CoV

Expression System: Baculovirus-Insect Cells

Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) Spike Protein (S1+S2 ECD, His)

TMPY-05676

Species: HCoV-HKU1

Expression System: Baculovirus-Insect Cells

Human coronavirus HKU1 (isolate N1) (HCoV-HKU1) Spike S1 Protein (His)

TMPY-02429

Species: HCoV-HKU1

Expression System: HEK293

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	A collection of 22706 bioactive compounds for high-throughput screening, high-content screening, cell induction and target identification.
L4200	FDA-Approved Drug Library	1729 compounds
	A unique collection of 1729 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS);
L3400	Clinical Compound Library	3480 compounds
	A unique collection of 3480 compounds in clinical trial phases for high throughput screening (HTS) and high content screening (HCS);
L9200	Drug Repurposing Compound Library	4630 compounds
	A unique collection of 4630 approved and clinical drugs for high throughput screening (HTS) and high content screening (HCS);
L7000	Bioactive Lipid Compound Library	385 compounds
	A unique collection of 385 bioactive lipids related compounds for high throughput screening (HTS) and high content screening (HCS), including Agonists & Antagonists, Endocannabinoids, Farnesyl/geranylgeranyl derivates, ...
L2140	Cancer Cell Differentiation Compound Library	413 compounds
	A unique collection of 413 cancer cell differentiation inducing compounds for high throughput and high content screening;
L1010	FDA-Approved & Pharmacopeia Drug Library	3158 compounds
	3158 compounds from marketed drugs for high throughput screening (HTS) and high content screening (HCS);
L5300	Mitochondria-Targeted Compound Library	830 compounds
	A unique collection of 830 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;
L4000	Bioactive Compound Library	14590 compounds
	A collection of 14590 small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification;