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Search Results for " m9 "

Targets

14

Compounds

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T8435 YM90K YM90K hydrochloride,6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)- GluR , iGluR
YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.
T4278 AM966 LPA Receptor , LPL Receptor
AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release.
T7954 YM976 PDE
YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM)
T10593 BPR1M97 Opioid Receptor
BPR1M97 is a mu opioid receptor (MOP) and neuropeptide-orphin FQ (NOP) receptor agonist with blood-brain barrier permeability and potency, with Kis values of 1.8 nM for MOP and 4.2 nM for NOP.BPR1M97 exhibits anti-injuri...
T40165 OM99-2 TFA OM99-2 TFA
OM99-2 TFA is an eight-residue peptidomimetic compound, functioning as a tight-binding inhibitor of human brain memapsin 2. It exhibits a high affinity for the target with a Ki value of 9.58 nM, making it a promising can...
T79272 BDM91514
BDM91514 enhances antibiotic efficacy by inhibiting AcrB, effectively curbing the proliferation of E. coli BW25113 with an EC90 of 8 μM when coupled with 8 μg/mL Pyridomycin. Additionally, BDM91514 exhibits favorable pla...
T70194 AM92016
AM92016 is a specific blocker of the time dependent delayed rectifier potassium current. AM92016 does not show any β-adrenoceptor blocking activity.
T78200 BDM91270
BDM91270 (compound 29) serves as an inhibitor of the E. coli AcrAB-TolC efflux pump, displaying an EC90 value of 0.6 μM against wild-type E. coli AcrB. It has applications in research on Escherichia coli drug resistance ...
T15768 LM985 Others
LM985 is one of a series of compounds based on the flavone ring structure. It has anti-tumor activities.
T24663 YM928 YM-928,YM 928
YM928 is an orally active antagonist of the AMPA receptor.
T70868 HM90822
HM90822 is a novel antagonist to the inhibitors of apoptosis (IAPs), potentiating cell death in EGFR-overexpressing non-small-cell lung cancer cells.
T69733 LM9
LM9 is a MyD88 inhibitor which prevents atherosclerosis by regulating inflammatory responses and oxidative stress in macrophages.
T40393 OM99-2 OM99-2
OM99-2 is an eight-residue peptidomimetic with a high affinity for human brain memapsin 2, exhibiting a Ki value of 9.58 nM. This compound represents a significant advancement in the development of BACE1 inhibitors and h...
T10294 AM9405 5-HT Receptor
AM9405 is a novel peripherally active cannabinoid type 1 (CB1) and serotonin type 3 receptor agonist. AM9405 inhibits twitch contraction of the ileum and the colon with IC 50 s of 45.71 and 0.076 nM, respectively. AM9405...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03343 EIF3K Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
EIF3K is a member of the eIF3 subunit K family. It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-...
TMPK-00553 ADAM9 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibu...
TMPH-01272 TRIM9 Protein, Human, Recombinant (His & SUMO) Human E. coli
E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and ma...
TMPY-02404 ADAM9 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
ADAM9 (A disintegrin and metallopeptidase domain 9, MDC9, meltrin gamma), is a type 1 transmembrane protein that has been associated with cancer development and metastases. ADAM9 is consistently overexpressed in various ...
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