Shopping Cart
Remove All
Your shopping cart is currently empty
Synonyms: PTK2B, PTK, PKB, FRNK, FAK2, CAKB
Anti-PYK2 Monoclonal Antibody
(6M943)

| Description | Anti-PYK2 Monoclonal Antibody (6M943) is a Mouse antibody targeting PYK2. Anti-PYK2 Monoclonal Antibody (6M943) can be used in WB,IHC. |
| Synonyms | PTK2B, PTK, PKB, FRNK, FAK2, CAKB |
| Ig Type | IgG2a |
| Clone | 6M943 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | PYK2: PTK2B protein tyrosine kinase 2 beta, also known as PTK2B, PKB, PTK, CAKB, FAK2, FRNK. Entrez Protein NP_004094. It is a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of PYK2 (aa815-997) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PTK2B |
| Gene ID | |
| Protein Name | Protein-tyrosine kinase 2-beta |
| Uniprot ID |
| Molecular Weight | Theoretical: 115.8 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
|---|

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.