tumour

Tumor-associated MUC1 epitope, a biologically active peptide, is the distinctive feature of MUC1 mucin—a significantly glycosylated type I transmembrane glycoprotein. Its extracellular domain comprises variable numbers of tandem repeats (VNTR) of a 20 amino acid sequence. This peptide is overexpressed on the surface of various human adenocarcinomas and hematological malignancies like multiple myeloma and B-cell lymphoma, rendering MUC1 a widely relevant target for immunotherapeutic approaches.

Carcinoembryonic antigen peptide 1 (CEA peptide) is a Carcinoembryonic Antigen (CEA) derived peptide. CEA is a broad-spectrum tumour marker, a glycoprotein produced by colorectal cancer tissues, which acts as an antigen to elicit an immune response.

Glutathione diethyl ester is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.

TNF-α (31-45), human (TFA), is a peptide of tumor necrosis factor-α (TNF alpha), an inflammatory cytokine that induces necrosis or apoptosis.