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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5001 | Nintedanib esylate | Intedanib,BIBF 1120 (esylate),Nintedanib Ethanesulfonate Salt,BIBF 1120 | VEGFR , FGFR , PDGFR |
Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β | |||
T68229 | Nintedanib esylate hemihydrate | ||
Nintedanib esylate hemihydrate is a potent inhibitor of multiple receptor tyrosine kinases (RTKs) and non-receptor tyrosine kinases (nRTKs). | |||
T7175 | Alflutinib mesylate | AST2818 mesylate | EGFR |
Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M. | |||
T72528 | NSC243928 mesylate | HuR | |
NSC243928 mesylate binds to human lymphocyte antigen 6 (LY6), a cell growth inhibitor with anticancer activity, and induces cell death in triple-negative breast cancer cells in a LY6K-dependent manner. | |||
T9789 | Cevidoplenib dimesylate hydrochloride | Syk | |
Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties. | |||
T19526 | Pradefovir mesylate | Pradefovir mesilate,Remofovir mesylate,Hepavir B | P450 |
Pradefovir mesylate (Hepavir B) is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with Km of 60 μM. | |||
T13564L2 | AZ7550 trimesylate salt | AZ7550 Mesylate,AZ7550 trimesylate salt (1421373-99-0 free base) | MLK |
AZ7550 trimesylate salt (AZ7550 Mesylate) is the active metabolite of ositinib, AZ7550 trimesylate salt inhibits IGF1R activity and can be used in the study of non-small cell lung cancer. | |||
T6144 | KB-R7943 mesylate | KB-R7943 | Na+/Ca2+ Exchanger , Autophagy |
KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM. | |||
T0425L | Pefloxacin Mesylate Dihydrate | Pefloxacinium mesylate dihydrate,1589 RB | Topoisomerase , Antibacterial , Antibiotic |
Pefloxacin Mesylate Dihydrate (1589 RB) , an antibacterial agent, restrains bacterial DNA replication by inhibiting DNA gyrase (topoisomerase). | |||
T9173 | HM-30181 mesylate monohydrate | P-gp | |
HM-30181 mesylate monohydrate is an oral P-glycoprotein (P-gp) inhibitor, used to enhance the oral bioavailability of P-gp substrate drugs. | |||
T2392 | Nafamostat mesylate | FUT-175 | Apoptosis , Serine/threonin kinase , SARS-CoV , Serine Protease |
Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. | |||
T11949 | Masupirdine mesylate | SUVN-502 mesylate,SVN-502 mesylate | 5-HT Receptor |
Masupirdine mesylate (SUVN-502 mesylate) is a selective 5-HT6 receptor antagonist that crosses the blood-brain barrier.Masupirdine mesylate is used in the study of neurological disorders such as Alzheimer's disease and d... | |||
T23588 | 9-CP-Ade Mesylate | 9-Cyclopentyladenine monomethanesulfonate,9 CP Ade Mesylate,9CPAde Mesylate | AChR |
9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase. | |||
T28978 | Tirilazad mesylate | U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate | Antiviral |
Tirilazad mesylate (U 74006F) is a non-glucocorticoid, lipid peroxidation inhibitor with antiviral activity and neuroprotective activity.Tirilazad mesylate confines intracellular intramembranous foci, attenuates spinal c... | |||
T7026L | Kukoamine B mesylate | Antioxidant | |
Kukoamine B mesylate is a novel cationic alkaloid derived from dermatophytes with antioxidant activity, inhibits LPS internalization in Kupffer and RAW 264.7 cells, and can be used to study acute inflammation and diabete... | |||
T71699 | Lanopepden mesylate | GSK 1322322 mesylate,GSK-1322322J mesylate | Antibacterial |
Lanopepden mesylate is a peptide deformylase inhibitor against Staphylococcus aureus. | |||
T28248 | Ono-3307 mesylate | Ono-3307,Ono3307,Ono 3307 | Protease |
Ono-3307 mesylate is a protease inhibitor with inhibitory effects on a variety of proteases.Ono-3307 mesylate has significant protective effects against liver injury in rats and inhibits the deposition of radiofibrillar ... | |||
T7861 | Flumatinib mesylate | HHGV678 mesylate | Bcr-Abl , PDGFR , c-Kit |
Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants. | |||
T7804 | Garenoxacin mesylate hydrate | Garenoxacin mesylate [USAN],BMS284756 (Mesylate hydrate) | Antibacterial |
Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains. | |||
T12059L | Mitoquinone mesylate | MitoQ mesylate,MitoQ10 mesylate | Reactive Oxygen Species |
Mitoquinone mesylate (MitoQ10 mesylate) is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage. |