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Results for "Wnt/beta-catenin" in TargetMol Product Catalog
  • Inhibitor Products
    26
    TargetMol | Activity
  • Recombinant Protein
    17
    TargetMol | inventory
  • Natural Products
    5
    TargetMol | natural
CHIR-99021
T2310252917-06-9
CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in mouse and human embryonic stem cells.
  • $36
In Stock
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
HLY78
T11571854847-61-3In house
HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt/β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling.
  • $34
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DK419
T151372102672-22-8In house
DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM. DK419 decreases protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin.It also induces production of pAMPK.
  • $79
In Stock
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SKL2001
T6989909089-13-0
SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.
  • $34
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TargetMol | Citations Cited
Tegatrabetan
T56421227637-23-1
Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.
  • $34
In Stock
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TargetMol | Citations Cited
Teplinovivint
T91511428064-91-8
Teplinovivint is a potent inhibitor of the Wnt/β-catenin signaling pathway, demonstrating anti-inflammatory properties with potential utility in tendinopathy research.
  • $135
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TargetMol | Inhibitor Sale
Mirodenafil dihydrochloride
TQ0126862189-96-6
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
  • $30
In Stock
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TargetMol | Inhibitor Sale
KY19382
T90252226664-93-1
KY19382 (2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382) is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β( IC50s of 19 and 10 nM, respectively). It activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.
  • $100
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Mirodenafil
T16079862189-95-5
Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
  • $44
In Stock
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Salinomycin sodium salt
TQ021555721-31-8
Salinomycin sodium salt (Sodium salinomycin), an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.
  • Inquiry Price
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L-quebrachitol
T5729642-38-6
L-quebrachitol is a natural product.L-quebrachitol may promote osteoblastogenesis by triggering the BMP-2-response as well as the Runx2, MAPK, and Wnt/β-catenin signaling pathway.
  • $31
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Astragaloside I
T392584680-75-1
Astragaloside I (Cyclosieversioside B) is a natural product isolated from Astragalus membranaceus. It can stimulate osteoblast differentiation through the Wnt/β-catenin signaling pathway and can be used to study osteogenic activity.
  • $47
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PNU-74654
T7204113906-27-7
PNU 74654 binds to β-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway.
  • $51
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TargetMol | Citations Cited
Wnt/β-catenin agonist 1
T133442305372-67-0
Wnt/β-catenin agonist 1 is an agonist of Wnt/β-catenin signalling pathway(EC50 of 0.27 μM).
  • $1,520
6-8 weeks
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KY1220
T15677292168-79-7
KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.
  • $44
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N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
TN7036883715-23-9
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) induces osteogenic differentiation and subsequent bone formation of mesenchymal stem cells by activating the canonical Wnt/β-catenin signaling pathway that can be used for osteoporosis research.
  • $43
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Cardiogenol C hydrochloride
T80051049741-55-0
Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).
  • $30
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Cardiogenol C
T2161671225-39-1
Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.
  • $38
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Wnt/β-catenin agonist 3
T9988912790-59-1
Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.
  • $68
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CWP232228
T109041144044-02-9
CWP232228, a potent and selective Wnt / β-catenin signaling inhibitor, antagonizes the binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting the growth of breast cancer and live
  • $233
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Pamidronic acid
T840040391-99-9
Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells
  • $33
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MSAB
T8710173436-66-3
MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.
  • $31
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Wnt/β-catenin agonist 2
T41094943820-93-7
Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and is an effective Wnt agonist. Wnt/β-catenin agonist 2 can be used in the study of diseases related to signal transduction and is closely related to cancer invasion and metastasis.
  • $49
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Triptonide
T5S105838647-11-9
1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, and this expression was suppressed by ERK1/2 and p38 MAPK inhibitors.
  • $51
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KYA1797K
T68681956356-56-1
KYA1797K is a highly potent and selective inhibitor. Wnt/β-catenin IC50 is 0.75 μM through TOPflash assay.
  • $41
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FH535
T2413108409-83-2
FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.
  • $32
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