Akt

Protein kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration.

Cat. No.	Product name	CAS No.	Purity
TN4637	Neogrifolin	23665-96-5	98%
TN4637	Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS ...
TN5050	Sprengerinin C	88861-91-0	98%
TN5050	Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can st...
T11743	Kanosamine hydrochloride	57649-10-2	98%
T11743	Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species. Kanosamine inhibits...
TN1594	DL-Syringaresinol	1177-14-6	98%
TN1594	(+)-Syringaresinol shows inhibitory activity of Helicobacter pylori motility with the IC50 value is 50 microg/ml.
T10274	AKT-IN-2	1295514-91-8	98%
T10274	AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).
TN2694	2,3-Dihydro-3-methoxywithaferin A	21902-96-5	98%
TN2694	2,3-Dihydro-3-methoxywithaferin A is a natural withanolide , is cytotoxic to human cancer cells, and is a candidate anticancer natural compound. It protects norm...
T19378	Ipfencarbazone	212201-70-2	98%
T19378	Ipfencarbazone herbicide agent, is a substance being developed for the control of weeds such as watergrass in rice.
TMA0291	Dehydroglyasperin D	517885-72-2	98%
TMA0291	Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 h...
T14925	Cenisertib	871357-89-0	98%
T14925	Cenisertib (AS-703569) is a multi-kinase inhibitor and blocks the activity of Aurora-kinase-A/B, AKT, ABL1, STAT5, and FLT3. Cenisertib inhibits tumor growth in ...
TN4213	Hirsutenone	41137-87-5	98%
TN4213	Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid pero...
TN3539	Broussonin A	73731-87-0	98%
TN3539	Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, tra...
TN5100	Taspine	602-07-3	98%
TN5100	Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of H...
TN3152	6-Acetonyldihydrochelerythrine	22864-92-2	98%
TN3152	6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therape...
TN4245	Icariside D2	38954-02-8	98%
TN4245	Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 uM, it induces apoptosis via alteration of expression o...
TN3517	Bisacurone	120681-81-4	98%
TN3517	Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced liver injury by suppressi...
TN1549	Damnacanthal	477-84-9	98%
TN1549	Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its...
TN1805	Isosilybin B	142796-22-3	98%
TN1805	Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway, it has anti-prostate cancer (PCA) activit...
T2S0606	Bakkenolide A	19906-72-0	98%
T2S0606	Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign...
TN1462	Cajanin	32884-36-9	98%
TN1462	Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol ef...
TN4374	Kaerophyllin	75590-33-9	98%
TN4374	Kaerophyllin has anti-fibrotic effects, it can protect the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting H...