| T1920 |
CapivasertibHOT |
Capivasertib (AZD5363) is a new-type orally available inhibitor of the serine/threonine protein kinase AKT (IC50s: 3/7/7 nM for Akt1/2/3).
|
| T1952 |
MK-2206 dihydrochlorideHOT |
MK-2206 is a highly specific inhibitor of Akt1/2/3 (IC50: 8/12/65 nM in cell-free assays) and no effect on the activities of 250 other protein kinases.
|
| T8969 |
API-1 |
API-1 is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .
|
| TN1269 |
3beta-Methoxy-2,3-dihydrowithaferin A |
3beta-Methoxy-2,3-dihydrowithaferin A has cytoprotective activity, it protects normal cells against stress.
|
| T4S1419 |
Praeruptorin A |
1. Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation 2. Prae...
|
| T5S1632 |
8-O-Acetylshanzhiside methyl ester |
8-O-Acetylshanzhiside methylester has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might b...
|
| T5574 |
Guggulsterone E&Z |
Guggulsterone E&Z is a 3-hydroxy steroid. It has a role as an androgen.
|
| T5736 |
CYNARIN |
CYNARIN is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.
|
| T7315 |
BAY1125976 |
BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)
|
| T7885 |
Afuresertib hydrochloride |
Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
|
| TN1033 |
Sennidin A |
Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM.
|
| TN1034 |
Sennidin B |
Sennidin B stimulates glucose incorporation in rat adipocytes.
|
| TN1189 |
13-Methylberberine |
13-Methylberberine shows anti-adipogenic effect on 3T3-L1 adipocytes, it has potential as an anti-obesity drug
|
| TN1215 |
2'-Methoxykurarinone |
2'-Methoxykurarinone has strong alpha-glucosidase inhibitory activities, with IC(50) values of 155 microM. 2'-Methoxykurarinone is a noncompetitive inhibitor of...
|
| TN1235 |
3,4,5-Tricaffeoylquinic acid |
3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α±- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like r...
|
| TN1245 |
3-Deoxysappanchalcone |
3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level.
|
| TN1379 |
Alphitolic acid |
Alphitolic acid is a potent Hh/GLI signaling inhibitor, it shows an important relationship between Hh/GLI signaling inhibition, the decrease of BCL2, and cytoto...
|
| TN1376 |
Alpha-Solanine |
Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut.
|
| T5S0168 |
Atractylenolide II |
1. Atractylenolide II has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation , ERK...
|
| TN1458 |
Buddlejasaponin IV |
Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-k...
|
| TN1461 |
(-)-Butin |
(-)-Butin has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuate...
|
| TN1462 |
Cajanin |
Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol e...
|
| TN1490 |
Chrysoeriol |
Chrysoeriol has antioxidant, antiinflammatory, antitumor, antimicrobial, antiviral, and free radical scavenging activities, it also shows selective bronchodilat...
|
| TN1549 |
Damnacanthal |
Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through it...
|
| TN1594 |
DL-Syringaresinol |
(+)-Syringaresinol shows inhibitory activity of Helicobacter pylori motility with the IC50 value is 50 microg/ml.
|
| TN1728 |
Hellebrigenin |
Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. ...
|
| TN1805 |
Isosilybin B |
Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway, it has anti-prostate cancer (PCA) activi...
|
| TN1889 |
Lupalbigenin |
Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins.
|
| TN1911 |
Marein |
Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation ...
|
| TN1990 |
Norathyriol |
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.
|
| TN2259 |
Taurocholic acid |
Taurocholic acid feeding shows cytoprotective effects on the biliary tree after adrenergic denervation of the liver; taurocholic acid feeding prevents tumor nec...
|
| T4S0498 |
Glaucocalyxin A |
1. Glaucocalyxin A-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases...
|
| T4489 |
AZD26 |
AZD-26 is an allosteric AKT inhibitor (IC50: 1.04 μM).
|
| T6S0525 |
Farrerol |
1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection a...
|
| T3001 |
Honokiol |
Honokiol is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.
|
| T6251 |
PF04691502 |
PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.
|
| T6849 |
Uprosertib |
Uprosertib (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respec...
|
| T1911 |
Afuresertib |
Afuresertib is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity.
|
| T2482 |
AT13148 |
AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.
|
| T0228 |
Methyl hesperidin |
Methyl Hesperidin, a flavanone glycoside (flavonoid) (C28H34O15), is abundant in citrus fruits. Its aglycone form is called hesperetin.
|
| T2420 |
PHT427 |
PHT-427 is a dual Akt (Ki: 2.7 μM) and PDPK1 (Ki: 5.2 μM) inhibitor (high-affinity binding for the PH domains of Akt and PDPK1).
|
| T3467 |
Miransertib |
ARQ-092 is an orally bioavailable, selective, and potent allosteric Akt inhibitor.
|
| T2492 |
Perifosine |
Perifosine is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.
|
| T3560 |
Desmethylanethol trithione |
ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. In the in vitro glucose-oxygen deprivation (OGD) model, ADT-...
|
| T3399 |
Psoralidin |
Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive ...
|
| T2789 |
Scutellarin |
Scutellarin, an active flavone isolated from Scutellaria baicalensis, can inhibit RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, and down-regu...
|
| T2790 |
Oridonin |
Oridonin is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with I...
|
| T2274 |
SC 79 |
SC79, a selective Akt activator, may be used to enhance Akt activity in various pathological and physiological conditions.
|
| T6065 |
Triciribine |
Triciribine is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.
|
| T12397 |
KP-23172 |
KP-23172 is a inhibitor of PI3-K/Akt pathway.
|
| T6817 |
Deguelin |
Deguelin is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.
|
| T3881 |
Vaccarin |
Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylatio...
|
| T2895 |
Lupeol |
Lupeol is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.
|
| T6139 |
A674563 |
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
|
| T2176 |
2,3-Butanedione 2-Monoxime |
2, 3-Butanedione 2-Monoxime is an inhibitor of skeletal and cardiac muscle contraction.
|
| T0033 |
Miltefosine |
Miltefosine is the treatment of visceral and cutaneous leishmaniasis drug , and is proceeding clinical trials for this in several countries. Several medical age...
|
| T3346 |
AKT inhibitor VIII |
AKT inhibitor VIII is a highly specific Akt1/2 inhibitor (IC50: 58/210 nM). The selectivity for Akt1 is higher about 36-fold than Akt3.
|
| T3729 |
Ethyl gallate |
Ethyl gallate obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-depende...
|
| T6304 |
AT7867 |
AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside th...
|
| T3132 |
SC66 |
SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 μg/ml, at 72 h).
|
| T6285 |
GSK690693 |
GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.
|
| T4046 |
BX517 |
BX-517 is a potent and selective inhibitor of PDK1.
|
| T4444 |
A-674563 HCl (552325-73-2(free base)) |
A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2...
|
| TN2328 |
Zeylenone |
Zeylenone has good antitumor efficacy, it inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways. Zeyl...
|
| T14034 |
3CAI |
3CAI is a specific inhibitor of AKT1 and AKT2.
|
| T6252 |
Ipatasertib |
Ipatasertib (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively.
|
| TN4244 |
Icariside B1 |
Icariside B1 shows inhibitory effects on LPS-induced NO production in RAW264.7 cells.
|
| TN3539 |
Broussonin A |
Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, tr...
|
| TN3655 |
Cimiside E |
Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1...
|
| TN3691 |
Communic acid |
Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmeti...
|
| TN3726 |
Cudraflavone B |
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and m...
|
| TN3753 |
Dalbergioidin |
Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyce...
|
| TN3806 |
Dehydroglyasperin C |
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemo...
|
| TMA0291 |
Dehydroglyasperin D |
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 ...
|
| TMA2474 |
Delta-Tocotrienol |
Delta-tocotrienol is a potential angiogenic inhibitor, it (2.5-5 microM) can significantly suppress human colorectal adenocarcinoma cells (DLD-1-CM) -induced tu...
|
| TMA1743 |
Ergosterol peroxide |
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fo...
|
| TN4038 |
Eupatolide |
Eupatolide has anti-inflammatory activity, it inhibits lipopolysaccharide-induced COX-2 and iNOS expression in RAW264.7 cells by inducing proteasomal degradatio...
|
| TN4046 |
Excisanin A |
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pot...
|
| TN4179 |
Haginin A |
Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB acti...
|
| TN4213 |
Hirsutenone |
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid per...
|
| TN4245 |
Icariside D2 |
Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 uM, it induces apoptosis via alteration of expression...
|
| TN3517 |
Bisacurone |
Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced liver injury by suppress...
|
| TN4263 |
Isoangustone A |
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation...
|
| TN4356 |
Jolkinolide A |
Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly i...
|
| TN4374 |
Kaerophyllin |
Kaerophyllin has anti-fibrotic effects, it can protect the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting ...
|
| TN4390 |
Kihadanin B |
Kihadanin B can repress the adipogenesis by decreasing lipid accumulation through the suppression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes.
|
| TN4506 |
(+)-Matairesinol |
(+)-Matairesinol exhibits immunomodulatory activity; it also shows inhibition of the discoloration of yellowtail dark muscle.
|
| TN4637 |
Neogrifolin |
Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS...
|
| TN4675 |
Nortrachelogenin |
Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth...
|
| TN4683 |
Nyasol |
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory...
|
| TN4932 |
Sageone |
Sageone represents a promising anticancer agent against gastric cancer that warrants further study, it synergizes with cisplatin cytotoxicity in SNU-1 human gas...
|
| TN5050 |
Sprengerinin C |
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can s...
|
| TN5100 |
Taspine |
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of ...
|
| T8656 |
CAY10404 |
CAY10404 is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apopto...
|
| T6139L |
A-674563 2HCl(552325-73-2(fb-2hcl)) |
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
|
| TN3525 |
Boehmenan |
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity i...
|
| TN3486 |
Bakkenolide IIIa |
Bakkenolide IIIa has antioxidant, and neuroprotective effects, it protects against cerebral damage by inhibiting AKT and ERK1/2 activation and inactivated NF-Î...
|
| T14152 |
Akt1 and Akt2-IN-1 |
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.
|
| T6S0619 |
Pachymic acid |
Pachymic acid is a natural product, and inhibits Akt and ERK signaling pathways.
|
| T13862 |
Recilisib |
Recilisib is a radioprotectant,can activate AKT, PI3K activities in cells.
|
| T10276 |
AKT Kinase Inhibitor |
AKT Kinase Inhibitor is an inhibitor of Akt kinase with anti-tumor activity.
|
| T10274 |
AKT-IN-2 |
AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).
|
| T10275 |
AKT-IN-3 |
AKT-IN-3 is a potent, orally active low hERG blocking Akt inhibitor (IC50: 1.4 nM, 1.2 nM, and 1.7 nM for Akt1, Akt2, and Akt3). AKT-IN-3 (compound E22) also ex...
|
| T14925 |
Cenisertib |
Cenisertib (AS-703569) is a multi-kinase inhibitor and blocks the activity of Aurora-kinase-A/B, AKT, ABL1, STAT5, and FLT3. Cenisertib inhibits tumor growth in...
|
| T15056 |
DB07107 |
DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM).
|
| T15374 |
Ipatasertib dihydrochloride |
Ipatasertib dihydrochloride is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18, and 8 nM for Akt1, Akt2, and Akt3, respectively).
|
| T13265 |
Urolithin B |
Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enh...
|
| T19378 |
Ipfencarbazone |
Ipfencarbazone herbicide agent, is a substance being developed for the control of weeds such as watergrass in rice.
|
| T11743 |
Kanosamine hydrochloride |
Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species. Kanosamine inhibit...
|
| T16104 |
ML-9 |
ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibi...
|
| T16155 |
MSN-125 |
MSN-125 effectively inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons protect primary neurons against glutamate excitotoxi...
|
| T5508 |
PF-AKT400 |
PF-AKT400 is a broadly selective and ATP-competitive inhibitor of Akt.
|
| T11928 |
M2698 |
M2698 can cross the blood-brain barrier and has anti-cancer activity. M2698 is an orally active, ATP competitive, selective p70S6K and Akt dual-inhibitor with ...
|
| TN3404 |
Altholactone |
Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of...
|
| T17280 |
(Z)-Guggulsterone |
(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-...
|
| T2S0606 |
Bakkenolide A |
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sig...
|
| T2S1040 |
Jolkinolide B |
Jolkinolide B has potent anti-inflammatory, and antitumor activities, it is able to enhance apoptosis of human leukemic HL-60 and THP-1 cells, at least in part,...
|
| T2S1975 |
Ponicidin |
Ponicidin has anti-leukemia, immunoregulatory and anti-inflammatory functions, it also has anti-viral function especially in the upper respiratory tract infecti...
|
| T3229 |
Cytochalasin D |
Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertili...
|
| T3S0209 |
Vincristine |
Vincristine-induced nociceptive painful sensation, may be due to its potential of antioxidative, neuroprotective and calcium channel inhibitory action.Vincristi...
|
| T4001 |
Euxanthone |
Euxanthone has vasorelaxation effect, may be through multiple pathways involved PKC-mediated signal pathway and calcium-independent pathway, it induces its vaso...
|
| T4A2399 |
Cinobufotalin |
Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide p...
|
| T7190 |
Actein |
Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblas...
|
| TN2691 |
2',3'-Dehydrosalannol |
2',3'-Dehydrosalannol possesses antifeedant activity against Spodptera litura. It shows anticancer effects on triple-negative breast cancer(TNBC), it inhibits c...
|
| TN2694 |
2,3-Dihydro-3-methoxywithaferin A |
2,3-Dihydro-3-methoxywithaferin A is a natural withanolide , is cytotoxic to human cancer cells, and is a candidate anticancer natural compound. It protects nor...
|
| TN3139 |
5alpha-Hydroxycostic acid |
5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may be a good drug candidate.
|
| TN3152 |
6-Acetonyldihydrochelerythrine |
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therap...
|
| TN3219 |
7,8-Didehydrocimigenol |
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity o...
|
| T1961 |
Vistusertib |
AZD2014 is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.
|
