h8

H-8 hydrochloride is a reversible and ATP-competitive PKA inhibitor. It can be used to study metabolic diseases.

H8-A5, a HDAC8 inhibitor, shows antiproliferation activity in MDA-MB-231 cancer cells.

IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μM, and 1.38 μM for IDH1R132H, IDH1R132C, and IDH1wt).

LH846 is a selective inhibitor of CK1δ with IC50 values of 290 nM for CK1δ, 1.3 μM for CK1ε, and 2.5 μM for CK1α, and exhibits no inhibitory activity at CK2.

ZH8965 is an orally active TAAR1-Gs/Gq agonist (EC50: 6.1/14.8 nM) that shows efficacy in alleviating antipsychotic-like phenotypes and cognitive deficits in an MK-801-induced psychosis model in mice. It is applicable for research related to schizophrenia.

ZH8659 hydrochloride is a trace amine-associated receptor 1 (TAAR1)-Gq agonist and can be utilized in research related to neurological disorders.

BtGH84 Activator I is a BtGH84 activator. It is the small molecule activator of a glycoside hydrolase.

Pyridinium, 1,1'-(thiodimethylene)bis(4-formyl-, dichloride, dioxime is a bioactive chemical.

ZH8667 is a TAAR1-Gs agonist that holds potential for schizophrenia research [1].

ZH8659 is a Gq agonist targeting the trace amine-associated receptor 1 (TAAR1) and has potential applications in schizophrenia research [1].

ZH8651, a TAAR1 agonist, activates both Gs and Gq signaling pathways and has potential applications in schizophrenia research [1].

Ginsenoside Rh8 is a natural product.

(±)-Prenalterol (H 80/62) is a new cardioselective positive inotropic compound that is an agonist of beta-2- and beta-1-adrenergic receptors and can be used to study chronic congestive heart failure.

Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.

DSPS (Dioctadecanoylphosphatidylserine) is a glycerophospholipid, an important phospholipid membrane component that plays a key role in cell cycle signaling. DSPS can regulate cellular activity and mediate apoptosis. DSPS is widely used as a nutritional supplement.

Norgestrel (WY-3707) is a synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes.

ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.

H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).

AM-2232 (UNII-40KCH8YIKP) is a potent and unselective agonist of the cannabinoid receptors.

H-89 is a selective and potent protein kinase A inhibitor (IC50: 48 nM), a candidate cardioprotectant, induces spatial learning impairment in rats, and can be used to study myocardial infarction.

ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.

AH 8532 is an opioid compound with analgesic effects and is effective in inhibiting the quinone-induced writhing response in mice, with an oral ED50 of 16 mg/kg.

AH 8529 is an orally active opioid compound with analgesic properties.

Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin.