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Anti-kynureninase/KYNU Antibody (4H809)
😃Good
Catalog No. TMAY-03223
Alias KYNUU, kynureninase
Anti-kynureninase/KYNU Antibody (4H809) is a Rabbit antibody targeting kynureninase/KYNU. Anti-kynureninase/KYNU Antibody (4H809) can be used in WB.
Anti-kynureninase/KYNU Antibody (4H809)
Anti-kynureninase/KYNU Antibody (4H809)
😃Good
Catalog No. TMAY-03223Alias KYNUU, kynureninase
Anti-kynureninase/KYNU Antibody (4H809) is a Rabbit antibody targeting kynureninase/KYNU. Anti-kynureninase/KYNU Antibody (4H809) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: WB Reactivity: Mouse |
| Alias | KYNUU, kynureninase |
| Ig Type | Rabbit IgG |
| Clone | 4H809 |
| Reactivity | Mouse |
| Verified Activity | Anti-KYNu rabbit monoclonal antibody at 1:500 dilution. -Lane A: NCI-H460 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:52 kDa. -Observed band size:52 kDa(We are unsure as to the identity of these extra bands.) |
| Application | WB |
| Recommended Dose | WB: 1:500-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse KYNU (rM KYNU; TMPY-02418; Q9CXF0; Met1-Ser464). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | KYNU (Kynureninase) is a Protein Coding gene. KYNU is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Genetic studies in the mouse and the human suggest that kynureninase activity may influence blood pressure and renal function. The gene coding kynureninase (KYNU) is also located on chromosome band 2q14-q23, where a linkage peak for essential hypertension was previously detected in the Chinese Han population. The results show that the rare KYNU variant Arg188Gln affects kynureninase activity and are consistent with the hypothesis that this mutation can predispose to essential hypertension. Diseases associated with KYNU include Hydroxykynureninuria and Vertebral, Cardiac, Renal, And Limb Defects Syndrome 2. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse KYNU protein (TMPY-02418) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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