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Anti-kynureninase/KYNU Antibody (4H809) (Synonyms: KYNUU, kynureninase)

Catalog No. TMAY-03223 Copy Product Info
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Anti-kynureninase/KYNU Antibody (4H809) is a Rabbit antibody targeting kynureninase/KYNU. Anti-kynureninase/KYNU Antibody (4H809) can be used in WB.

Anti-kynureninase/KYNU Antibody (4H809)

Copy Product Info
🥰Excellent
Catalog No. TMAY-03223
Synonyms KYNUU, kynureninase

Anti-kynureninase/KYNU Antibody (4H809) is a Rabbit antibody targeting kynureninase/KYNU. Anti-kynureninase/KYNU Antibody (4H809) can be used in WB.

Anti-kynureninase/KYNU Antibody
(4H809)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-kynureninase/KYNU Antibody (4H809) is a Rabbit antibody targeting kynureninase/KYNU. Anti-kynureninase/KYNU Antibody (4H809) can be used in WB.
SynonymsKYNUU, kynureninase
Ig Type
Rabbit IgG
Clone
4H809
Reactivity
Mouse
Specificity
Mouse kynureninase/KYNU
Verified Activity
Anti-KYNu rabbit monoclonal antibody at 1:500 dilution.
-Lane A: NCI-H460 Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.
-Developed using the Odyssey technique.
-Performed under reducing conditions.
-Predicted band size:52 kDa.
-Observed band size:52 kDa(We are unsure as to the identity of these extra bands.)
Application
Recommended Dose
WB: 1:500-1:2000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse KYNU (rM KYNU; TMPY-02418; Q9CXF0; Met1-Ser464).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundKYNU (Kynureninase) is a Protein Coding gene. KYNU is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Genetic studies in the mouse and the human suggest that kynureninase activity may influence blood pressure and renal function. The gene coding kynureninase (KYNU) is also located on chromosome band 2q14-q23, where a linkage peak for essential hypertension was previously detected in the Chinese Han population. The results show that the rare KYNU variant Arg188Gln affects kynureninase activity and are consistent with the hypothesis that this mutation can predispose to essential hypertension. Diseases associated with KYNU include Hydroxykynureninuria and Vertebral, Cardiac, Renal, And Limb Defects Syndrome 2.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Mouse KYNU protein (TMPY-02418)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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