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HER1

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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Trastuzumab
T9912180288-69-1
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer.
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TargetMol | Inhibitor Hot
Cetuximab
Cetuximab (anti-EGFR), C225
T9905205923-56-4
Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor receptor (EGFR) (Kd=0.201 nM). Cetuximab has antitumor activity, inhibiting tumor cell proliferation and inducing apoptosis.
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TargetMol | Inhibitor Hot
Matuzumab
EMD-72000, EMD72000, EMD 72000
T9922339186-68-4
Matuzumab (EMD 72000) is a humanized monoclonal antibody targeting EGFR with potential anticancer activity that blocks EGFR activation and downstream signaling for the study of non-small cell lung cancer.
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Panitumumab
Panitumumab(anti-EGFR)
T9927339177-26-3
Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR).
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Laprituximab emtansine
J2898A-SMCC-DM1, IMGN-289
T9901A-0241622327-37-0
Laprituximab emtansine (IMGN-289), an immunotoxin targeting HER1, is an EGFR antibody-drug conjugate (ADC) composed of J2898A antibody, DM1 (anti-microtubule agent), and the SMCC thioether linker, utilized in cancer research [1] [2] [3].
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