iGluR

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate.[1] They mediate the majority of excitatory synaptic transmission throughout the central nervous system and are key players in synaptic plasticity, which is important for learning and memory. iGluRs have been divided into four subtypes on the basis of their ligand binding properties (pharmacology) and sequence similarity: AMPA receptors, kainate receptors, NMDA receptors and delta receptors.

Cat. No.	Product name	CAS No.	Purity
T6618	Orphenadrine Citrate	4682-36-4	98%
T6618	Orphenadrine Citrate is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.
T3407	Rapastinel	117928-94-6	98%
T3407	Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.
T23490	UBP310	902464-46-4	98%
T23490	GLUK5 kainate receptor antagonist
T15820	Mibampator	375345-95-2	98%
T15820	Mibampator is an effective and selective AMPA receptor potentiator.
T20571	Cis-PDA	46026-75-9	98%
T20571	cis-PDA, a general ionotropic receptor antagonist, acts by blocking NMDA, AMPA, and kainate mediated responses. It also acts as a partial NMDA receptor agonist.
TQ0289	LY450108	376594-67-1	98%
TQ0289	LY450108 is a potentiator of the AMPA receptor.
T3407L	Rapastinel acetate	491872-39-0	98%
T3407L	Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.
T61518	TAK-653	1358751-06-0	98%
T61518	TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats.
T12187L	Naspm trihydrochloride	1049731-36-3	98%
T12187L	Naspm trihydrochloride is a synthetic analogue of Joro spider toxin and is an antagonist of calcium permeable AMPA (CP-AMPA) receptors.
T4096	Quinolinic acid	89-00-9
T4096	Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
T22542	1-Aminocyclobutanecarboxylic acid	22264-50-2
T22542	1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].
T8435	YM90K	154164-30-4	100%
T8435	YM90K hydrochloride is an antagonist of AMPA receptor.
T8459	DNQX disodium salt	1312992-24-7	100%
T8459	DNQX Disodium is a water-soluble form of selective antagonist of non-NMDA receptor
T10930	D-AP5	79055-68-8	100%
T10930	D-AP5 is a NMDA receptor antagonist.
T7706	LY-404187	211311-95-4	100%
T7706	LY404187 is a positive allosteric modulator of AMPA receptors
T10774	CFM-2	178616-26-7	97.16%
T10774	CFM-2 is a selective non-competitive AMPAR antagonist.
T7355	IC87201	866927-10-8	97.44%
T7355	IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain.
T4113	NBQX	118876-58-7	97.66%
T4113	Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.
T7591	Coluracetam	135463-81-9	98%
T7591	Coluracetam(MKC-231) is a Choline Uptake Enhancer.
T7580	CX546	215923-54-9	98%
T7580	CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.