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iGluR

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate.[1] They mediate the majority of excitatory synaptic transmission throughout the central nervous system and are key players in synaptic plasticity, which is important for learning and memory. iGluRs have been divided into four subtypes on the basis of their ligand binding properties (pharmacology) and sequence similarity: AMPA receptors, kainate receptors, NMDA receptors and delta receptors.
Cat. No. Product name CAS No. Purity Chemical Structure
T23490 UBP310 902464-46-4 98%
GLUK5 kainate receptor antagonist
T3407 Rapastinel 117928-94-6 98%
Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.
T22542 1-Aminocyclobutanecarboxylic acid 22264-50-2 98%
1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].
T20571 Cis-PDA 46026-75-9 98%
cis-PDA, a general ionotropic receptor antagonist, acts by blocking NMDA, AMPA, and kainate mediated responses. It also acts as a partial NMDA receptor agonist.
T12187L Naspm trihydrochloride 1049731-36-3 98%
Naspm trihydrochloride is a synthetic analogue of Joro spider toxin and is an antagonist of calcium permeable AMPA (CP-AMPA) receptors.
T72662 NMDAR/TRPM4-IN-2 2243506-33-2 98%
NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retina...
T16451 PEAQX tetrasodium hydrate T16451 98%
PEAQX tetrasodium hydrate is an orally available NMDA antagonist that is potent and selective. The IC50 value of PEAQX tetrasodium hydrate (459836-30-7 free base...
T4096 Quinolinic acid 89-00-9 98%
Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
TQ0289 LY450108 376594-67-1 98%
LY450108 is a potentiator of the AMPA receptor.
T8459 DNQX disodium salt 1312992-24-7 98%
DNQX Disodium is a water-soluble form of selective antagonist of non-NMDA receptor
T8435 YM90K 154164-30-4 98%
YM90K hydrochloride is an antagonist of AMPA receptor.
T10930 D-AP5 79055-68-8 98%
D-AP5 is a NMDA receptor antagonist.
T7706 LY-404187 211311-95-4 98%
LY404187 is a positive allosteric modulator of AMPA receptors
T16801 (RS)-(Tetrazol-5-yl)glycine 138199-51-6 98%
(RS)-(Tetrazol-5-yl)glycine (D,L-(tetrazol-5-yl)glycine) is an effective and selective N-methyl-D-aspartate receptor agonist. (RS)-(Tetrazol-5-yl)glycine has EC5...
T12406 PEPA 141286-78-4 98%
PEPA is an allosteric AMPA receptors modulator; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.
T10774 CFM-2 178616-26-7 98%
CFM-2 is a selective non-competitive AMPAR antagonist.
T7355 IC87201 866927-10-8 98%
IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain.
T15820 Mibampator 375345-95-2 98%
Mibampator is an effective and selective AMPA receptor potentiator.
T7108 Omberacetam 157115-85-0 98%
Omberacetam is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to other rel...
T7591 Coluracetam 135463-81-9 98%
Coluracetam(MKC-231) is a Choline Uptake Enhancer.
UBP310
T23490
GLUK5 kainate receptor antagonist
Rapastinel
T3407
Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.
1-Aminocyclobutanecarboxylic acid
T22542
1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].
cis-PDA
T20571
cis-PDA, a general ionotropic receptor antagonist, acts by blocking NMDA, AMPA, and kainate mediated responses. It also acts as a partial NMDA receptor agonist.
Naspm trihydrochloride
T12187L
Naspm trihydrochloride is a synthetic analogue of Joro spider toxin and is an antagonist of calcium permeable AMPA (CP-AMPA) receptors.
NMDAR/TRPM4-IN-2
T72662
NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retina...
PEAQX tetrasodium hydrate
T16451
PEAQX tetrasodium hydrate is an orally available NMDA antagonist that is potent and selective. The IC50 value of PEAQX tetrasodium hydrate (459836-30-7 free base...
Quinolinic acid
T4096
Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
LY450108
TQ0289
LY450108 is a potentiator of the AMPA receptor.
DNQX disodium salt
T8459
DNQX Disodium is a water-soluble form of selective antagonist of non-NMDA receptor
YM90K
T8435
YM90K hydrochloride is an antagonist of AMPA receptor.
D-AP5
T10930
D-AP5 is a NMDA receptor antagonist.
LY-404187
T7706
LY404187 is a positive allosteric modulator of AMPA receptors
(RS)-(Tetrazol-5-yl)glycine
T16801
(RS)-(Tetrazol-5-yl)glycine (D,L-(tetrazol-5-yl)glycine) is an effective and selective N-methyl-D-aspartate receptor agonist. (RS)-(Tetrazol-5-yl)glycine has EC5...
PEPA
T12406
PEPA is an allosteric AMPA receptors modulator; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.
CFM-2
T10774
CFM-2 is a selective non-competitive AMPAR antagonist.
IC87201
T7355
IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain.
Mibampator
T15820
Mibampator is an effective and selective AMPA receptor potentiator.
Omberacetam
T7108
Omberacetam is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to other rel...
Coluracetam
T7591
Coluracetam(MKC-231) is a Choline Uptake Enhancer.
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