iGluR

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate.[1] They mediate the majority of excitatory synaptic transmission throughout the central nervous system and are key players in synaptic plasticity, which is important for learning and memory. iGluRs have been divided into four subtypes on the basis of their ligand binding properties (pharmacology) and sequence similarity: AMPA receptors, kainate receptors, NMDA receptors and delta receptors.

Cat. No.	Product name	CAS No.	Purity
T23490	UBP310	902464-46-4	98%
T23490	GLUK5 kainate receptor antagonist
T3407	Rapastinel	117928-94-6	98%
T3407	Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.
T22542	1-Aminocyclobutanecarboxylic acid	22264-50-2	98%
T22542	1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].
T20571	Cis-PDA	46026-75-9	98%
T20571	cis-PDA, a general ionotropic receptor antagonist, acts by blocking NMDA, AMPA, and kainate mediated responses. It also acts as a partial NMDA receptor agonist.
T12187L	Naspm trihydrochloride	1049731-36-3	98%
T12187L	Naspm trihydrochloride is a synthetic analogue of Joro spider toxin and is an antagonist of calcium permeable AMPA (CP-AMPA) receptors.
T72662	NMDAR/TRPM4-IN-2	2243506-33-2	98%
T72662	NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retina...
T16451	PEAQX tetrasodium hydrate	T16451	98%
T16451	PEAQX tetrasodium hydrate is an orally available NMDA antagonist that is potent and selective. The IC50 value of PEAQX tetrasodium hydrate (459836-30-7 free base...
T4096	Quinolinic acid	89-00-9	98%
T4096	Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
TQ0289	LY450108	376594-67-1	98%
TQ0289	LY450108 is a potentiator of the AMPA receptor.
T8459	DNQX disodium salt	1312992-24-7	98%
T8459	DNQX Disodium is a water-soluble form of selective antagonist of non-NMDA receptor
T8435	YM90K	154164-30-4	98%
T8435	YM90K hydrochloride is an antagonist of AMPA receptor.
T10930	D-AP5	79055-68-8	98%
T10930	D-AP5 is a NMDA receptor antagonist.
T7706	LY-404187	211311-95-4	98%
T7706	LY404187 is a positive allosteric modulator of AMPA receptors
T16801	(RS)-(Tetrazol-5-yl)glycine	138199-51-6	98%
T16801	(RS)-(Tetrazol-5-yl)glycine (D,L-(tetrazol-5-yl)glycine) is an effective and selective N-methyl-D-aspartate receptor agonist. (RS)-(Tetrazol-5-yl)glycine has EC5...
T12406	PEPA	141286-78-4	98%
T12406	PEPA is an allosteric AMPA receptors modulator; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.
T10774	CFM-2	178616-26-7	98%
T10774	CFM-2 is a selective non-competitive AMPAR antagonist.
T7355	IC87201	866927-10-8	98%
T7355	IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain.
T15820	Mibampator	375345-95-2	98%
T15820	Mibampator is an effective and selective AMPA receptor potentiator.
T7108	Omberacetam	157115-85-0	98%
T7108	Omberacetam is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to other rel...
T7591	Coluracetam	135463-81-9	98%
T7591	Coluracetam(MKC-231) is a Choline Uptake Enhancer.