spike

Denifanstat (FASN-IN-2) is a fatty acid synthase (FASN) inhibitor (IC50=0.052 μM, EC50=0.072 μM) with selective and oral activity. Denifanstat has been used in studies of steatohepatitis.

Emodin (Frangula emodin) is an 11β-HSD1 inhibitor with a selective IC50 of 186 and 86 nM against 11β-HSD1 in humans and mice, respectively. Emodin has antiviral, anti-inflammatory, and anti-cancer effects. Emodin can improve metabolic disorders in diet-induced obese mice.

SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2 (ACE2).

Anti-SARS-CoV-2 Spike mAb (CR3022) is a human monoclonal IgG1 antibody produced from CHO cells, which specifically targets the S1 domain of the Spike protein in both SARS-CoV and SARS-CoV-2.

Anti-Spike-RBD mAb is a CHO cell-derived human monoclonal IgG1 antibody that potentially treats SARS-CoV-2 by blocking the interaction between the spike protein and ACE2[1].

The Anti-Spike-RBD Single Domain mAb is a monoclonal antibody derived from CHO cells in Alpaca. It is composed of VHH-huFc and exhibits a strong affinity for the SARS-CoV-2 RBD. [1]

The COVID-19 Spike Protein mRNA, responsible for expressing the COVID-19 spike protein, is crucial for evaluating RNA delivery, translation efficiency, and cell viability. Positioned on the membrane surface, this spike protein facilitates virus entry into cells by binding to host cell membrane receptors and promoting membrane fusion. It serves as a significant action site for neutralizing antibodies and represents a primary focus in vaccine development [1].

COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) formulated with the novel coronavirus pneumonia spike protein, positioned on the membrane surface. It is designed for applications such as RNA delivery, translation efficiency, and cell viability assessment. This spike protein facilitates the COVID-19 virus's entry into host cells by binding to cell membrane receptors and enabling membrane fusion, making it a critical focal point for host neutralizing antibodies and vaccine development [1].

Anti-MERS-CoV Spike Antibody (3I167) is a Rabbit IgG monoclonal antibody targeting MERS-CoV MERS-CoV Spike.

Anti-SARS-CoV/SARS-CoV-2 Spike Antibody (2J777) is a mouse (variable region) / human (kappa / IgG1 constant) chimeric monoclonal antibody targeting SARS SARS-CoV/SARS-CoV-2 Spike.

Anti-SARS-CoV/SARS-CoV-2 Spike Antibody (9J88) is a mouse (variable region) / human (kappa / IgG1 constant) chimeric monoclonal antibody targeting SARS SARS-CoV/SARS-CoV-2 Spike.

Anti-SARS-CoV-2 Omicron (BA.4/BA.5/BA.2.75) Spike RBD Specific Antibody (3M568) is a mouse (variable region) / human (kappa / IgG1 constant) chimeric monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Omicron (BA.4/BA.5/BA.2.75) Spike RBD Specific.

Anti-SARS-CoV-2 Alpha Spike RBD Specific Antibody (4J592) is a mouse (variable region) / human (kappa / IgG1 constant) chimeric monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Alpha Spike RBD Specific.

Anti-SARS-CoV-2 Delta Spike RBD Specific Antibody (2J642) is a mouse (variable region) / human (kappa / IgG1 constant) chimeric monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Delta Spike RBD Specific.

Anti-SARS-CoV-2 Spike Antibody (1W101) is a Mouse IgG1 monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Spike.

Anti-SARS-CoV-2 Spike Antibody (7G286) is a Mouse IgG1 monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Spike.

Anti-SARS-CoV-2 Spike Antibody (3F207) is a Mouse IgG1 monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Spike.

Anti-SARS-CoV-2 Spike Antibody (1M7) is a Mouse IgG1 monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Spike.

Anti-SARS-CoV-2 Spike Antibody (5F835) is a Mouse IgG1 monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Spike.

Anti-SARS-CoV-2 Spike Antibody (6A521) is a Mouse IgG2b monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Spike.

Anti-SARS-CoV-2 Spike Antibody (6I261) is a Mouse IgG2b monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Spike.

Anti-SARS-CoV-2 Spike Antibody (1H528) is a Rabbit IgG monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Spike.

Anti-SARS-CoV-2 Spike Antibody (5I143) is a Rabbit IgG monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Spike.

Anti-SARS-CoV-2 Spike Antibody (7W739) is a Rabbit IgG monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Spike.