reversibly — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4880	L-Dihydroorotic acid		Others , Endogenous Metabolite
	L-Dihydroorotic acid, also known as (S)-4,5-dihydroorotate or dihydro-L-orotate, belongs to the class of organic compounds known as alpha amino acids and derivatives. Within the cell, L-dihydroorotic acid is primarily lo...		Others , Endogenous Metabolite
T1465	Mupirocin	Pseudomonic acid,BRL-4910A	DNA/RNA Synthesis , Antibacterial , Antibiotic
	Mupirocin (BRL-4910A) is a RNA synthetase inhibitor antibacterial. It has shown excellent activity against gram-positive staphylococci and streptococci.		DNA/RNA Synthesis , Antibacterial , Antibiotic
T8148	Mupirocin calcium hydrate	Mupirocin calcium	Others , Antibacterial , Antibiotic
	Mupirocin calcium hydrate is an antibiotic produced by Pseudomonas fluorescens, showed a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria		Others , Antibacterial , Antibiotic
T2008	LY294002	LY 294002,NSC 697286,SF 1101	Apoptosis , DNA-PK , Casein Kinase , PI3K , Autophagy
	LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM). LY294002 is also an inhibitor of DNA-PK (IC50=1.4 μM) and an inhibitor of CK2 (IC50=98 nM). LY294002 ...		Apoptosis , DNA-PK , Casein Kinase , PI3K , Autophagy
T4079	LY-294002 hydrochloride	SF 1101,LY 294002,NSC 697286	PI3K
	LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation...		PI3K
T2404	Vonoprazan fumarate	TAK-438	ATPase
	Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.		ATPase
T6617	Optovin		TRP/TRPV Channel
	Optovin is a TRPA1 activator, which is reversibly photoactivated.		TRP/TRPV Channel
T21839L	10Panx Acetate	10Panx Acetate(955091-53-9 Free base)	Others
	10Panx Acetate is a mimetic inhibitory peptide that readily and reversibly inhibits the panx1 currents.		Others
T6463	Deoxyarbutin		Tyrosinase
	DeoxyArbutin(IC50=50 nM) inhibits tyrosinase activity reversibly.		Tyrosinase
T1473	Trilostane	Win 24540	Dehydrogenase
	Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly inhibits 3 beta-hydroxysteroid dehydrogenase delta 5-4 isomerase in the adrenal cortex.		Dehydrogenase
T4917	Dehydroascorbic acid	(L)-Dehydroascorbic acid	Endogenous Metabolite
	L-Dehydro Ascorbic Acid is the reversibly oxidized form of ascorbic acid;Dehydroascorbic acid ((L)-Dehydroascorbic acid), a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experi...		Endogenous Metabolite
T4348	Syk Inhibitor II		5-HT Receptor , Syk
	Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).		5-HT Receptor , Syk
T12437	PF429242 dihydrochloride		S1P Receptor
	PF429242 dihydrochloride is a reversible and competitive inhibitor of S1P (IC50 of 175 nM).		S1P Receptor
T5410	PD158780		EGFR
	PD 158780 reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor superfamily: EGFR, ErbB2, ErbB3, and ErbB4 (IC50s: 8μM, 49 nM, 52 nM, and 52 nM in cell assay).		EGFR
T4093	Fabomotizole hydrochloride	Afobazole hydrochloride,CM346 hydrochloride	MAO
	Fabomotizole hydrochloride (CM346 hydrochloride), an anxiolytic drug, produces anxiolytic and neuroprotective effects. The mechanism of Afobazole remains poorly defined, however, with GABAergic, NGF, and BDNF release pro...		MAO
T3052	Sancycline	Bonomycin,Norcycline,Sancyclinum,6-Demethyl-6-deoxytetracycline	Antibacterial
	Sancycline (Bonomycin) is a rare semi-synthetic tetracycline, acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.		Antibacterial
T1535	Sodium 4-phenylbutyrate	Sodium Phenylbutyrate,Buphenyl,TriButyrate	Apoptosis , HDAC , Autophagy
	Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II histone deacetylases (HDACs )resulting in a global increase in gene expression, decreased cellular proliferation, inc...		Apoptosis , HDAC , Autophagy
T4680L	HC067047 Hydrochloride(883031-03-6 free base)		TRP/TRPV Channel
	HC-067047 hydrochloride is a potent and selective TRPV4 antagonist. HC-067047 hydrochloride reversibly inhibited currents through the human, rat, and mouse TRPV4 orthologs with IC50 values of 486 nM, 133nM, and 17 nM, re...		TRP/TRPV Channel
T6651	Safinamide mesylate	PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate	MAO , Monoamine Oxidase
	Safinamide mesylate (EMD 1195686 mesylate) , a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.		MAO , Monoamine Oxidase
T6645	Ropivacaine hydrochloride monohydrate	Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,LEA-103 HCl	Potassium Channel , Sodium Channel
	Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.		Potassium Channel , Sodium Channel