piperidine

Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy.

Cyproheptadine hydrochloride is an effective orally active 5-HT2A receptor antagonist with antidepressant, anti-serotonin, and antiplatelet activities. It can be used for research on thromboembolic diseases and for the establishment of diabetes models.

Mesoridazine Besylate (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. It is a metabolite of thioridazine.

Piperidine-MO-1 is a dopamine receptor modulator, with an ED50 of 68 μmol/kg on increase of DOPAC in the rat striatum.

BMS-1166-n-piperidine-co-n-piperazine dihydrochloride, a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor, inhibits the PD-1/PD-L1 interaction with an IC50 of 39.2 nM. It contains the target protein PD-1/PD-L1 ligand and PROTAC linker, which can be used to synthesize PROTAC PD-1/PD-L1 degrader-1 and has anticancer activity. Additionally, it serves as a diluent for the preparation of tablets for direct compression.

4-(4-Fluorobenzoyl)piperidine hydrochloride, with CAS No. 25519-78-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-(4-Fluorobenzoyl)piperidine hydrochloride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-(9H-fluoren-9-ylmethoxycarbonylamino)-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester is a substituted piperidine derivative widely used in organic synthesis as a linker to form peptide and peptidomimetic molecules, and is widely used in peptide synthesis and peptide mimicry, as well as in the synthesis of pharmaceuticals, biopolymers and other organic molecules.

4-Methyl-1-(4-methylphenyl)piperidine-2,6-dione ,with CAS No. 883022-85-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Methyl-1-(4-methylphenyl)piperidine-2,6-dione provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-[5-Methyl-2-(trifluoromethyl)-3-furoyl]piperidine ,with CAS No. 936083-19-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-[5-Methyl-2-(trifluoromethyl)-3-furoyl]piperidine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.

4-(2-KETO-1-BENZIMIDAZOLINYL)PIPERIDINE, with CAS No. 20662-53-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-(2-KETO-1-BENZIMIDAZOLINYL)PIPERIDINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-(DIPHENYLMETHOXY)PIPERIDINE, with CAS No. 65214-86-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-(DIPHENYLMETHOXY)PIPERIDINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-(1H-Pyrazol-1-yl)-piperidine 2HCl, with CAS No. 1181458-83-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-(1H-Pyrazol-1-yl)-piperidine 2HCl provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Spiro[isochroman-1,4'-piperidine] ,with CAS No. 180160-97-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Spiro[isochroman-1,4'-piperidine] provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

N-piperidine Ibrutinib hydrochloride is a potent BTK inhibitor, a BTK ligand, inhibits WT BTK and C481S BTK, which can be used to synthesize a range of PROTAC molecules.N-piperidine Ibrutinib hydrochloride has potential anticancer N-piperidine Ibrutinib hydrochloride has potential anticancer activity, inhibiting the growth and proliferation of cancer cells.

4-{2-[(3R,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

Thalidomide-piperidine is an E3 ubiquitin ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugates) that can be utilized in the synthesis of SMART1.

Thalidomide-piperidine-C2-piperazine-Boc is an E3 Ligase Ligand-linker conjugate comprising a cereblon ligand based on Thalidomide and a linker. This compound is utilized in the synthesis of PROTAC.

(S)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 is a conjugate that serves as both an E3 ubiquitin ligase ligand and a linker for NX-2127.

4-Hydroxy-1-(2-phenylethyl)piperidine is a synthetic ligand for muscarinic acetylcholine receptors (mAChR) or non-opioid intracellular sigma-1 receptors (σ1 receptors). It serves as a metabolite of the opioid compounds furanylfentanyl and 4-fluoroisobutyryl fentanyl (FIBF).

Thalidomide-piperidine-C-Pip-C2-Pip-C2-OH (Compound C6) is a conjugate linking a ligand and an E3 ligase, which is utilized in the synthesis of PROTAC PARP1 degrader-30.

(2R,3S)-Boc-3-TBSO-2-hydroxymethyl-piperidine is a heterocyclic compound used in organic synthesis and biochemical experiments.

3-(4-Bromo-2-fluorophenyl)piperidine-2,6-dione is a CRBN-type E3 ubiquitin ligase ligand, which can be used in the preparation of PROTACs.

3-(4-Bromo-2-chlorophenyl)piperidine-2,6-dione acts as a ligand for CRBN type E3 ubiquitin ligase and is useful in the synthesis of PROTAC.