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Search Results for " w7 "

17

Compounds

Cat No. Product Name Synonyms Targets
T20792 W-7 hydrochloride W 7 HCl,W7 HCl,W-7 HCl CaMK , Apoptosis , Myosin , PDE
W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride induces apoptosis and has antitumor activity.
T35095 W 7 BRN 2888957,W7,W-7
W 7 is a biochemical.
T1800 GW788388 GW 788388 ALK , TGF-beta/Smad
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.
T15453 GW7647 PPAR
GW7647 is a potent agonist of PPARα (EC50s: 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ, and PPARδ, respectively).
T8866 GW779439X Apoptosis , Antibacterial , CDK , Aurora Kinase
GW779439X is an inhibitor of CDK.
T15633 JW74 Wnt/beta-catenin
JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).
T6079 NVP-ADW742 ADW742,ADW,GSK 552602A Apoptosis , IGF-1R
NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
T7805 GW791343 dihydrochloride GW791343 (HCl) P2X Receptor
GW791343 dihydrochloride (GW791343 (HCl)) is a P2X7 allosteric modulator.
TP1474 LXW7 Integrin
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. LXW7 is a disulfide cyclic octa-pepti...
TP2148 LXW7 TFA (1313004-77-1 free base) LXW7 TFA Integrin
LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor with an anti-inflammatory effect. LXW7 has a high binding affinity to αvβ3 integrin (IC50: 0.68 μM). It increases the phosphorylation...
T15452 GW7604 Others
GW7604 is an antiestrogen and it also is the metabolite of GW5638. GW5638 is an antagonist of high-affinity estrogen receptor (ER).
T75724 LXW7 TFA
LXW7 TFA, a cyclic peptide encompassing Arg-Gly-Asp (RGD), serves as an inhibitor of integrin αvβ3. It demonstrates high binding affinity towards αvβ3 integrin, evidenced by an IC50 value of 0.68 μM. Additionally, LXW7 T...
T27513 GW7845 GW 7845,GW-7845
GW7845, an L-tyrosine derivative, is a PPAR-γ agonist.
T24123 GW780056X GW-780056-X,GW 780056 X
GW780056X is a selective inhibitor of cyclin-dependent kinase. GW780056X is also an inhibitor of Yes1 kinase. It is an inhibitor of binding or entry into cells for the Lassa Virus.
T6526 GW791343 trihydrochloride GW791343 3HCl P2X Receptor
GW791343 trihydrochloride (GW791343 3HCl) is aHCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7.
T35103 W7477 BRN 0626598,W 7477,W-7477,CP 14304
W7477 is a biochemical.
T11519 GW768505A free base Others
GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2 (pIC50: 7.81 for VEGFR2) with anti-angiogenic activity.
TargetMol