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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T20792 | W-7 hydrochloride | W 7 HCl,W7 HCl,W-7 HCl | CaMK , Apoptosis , Myosin , PDE |
W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride induces apoptosis and has antitumor activity. | |||
T35095 | W 7 | BRN 2888957,W7,W-7 | |
W 7 is a biochemical. | |||
T1800 | GW788388 | GW 788388 | ALK , TGF-beta/Smad |
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities. | |||
T15453 | GW7647 | PPAR | |
GW7647 is a potent agonist of PPARα (EC50s: 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ, and PPARδ, respectively). | |||
T8866 | GW779439X | Apoptosis , Antibacterial , CDK , Aurora Kinase | |
GW779439X is an inhibitor of CDK. | |||
T15633 | JW74 | Wnt/beta-catenin | |
JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM). | |||
T6079 | NVP-ADW742 | ADW742,ADW,GSK 552602A | Apoptosis , IGF-1R |
NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit. | |||
T7805 | GW791343 dihydrochloride | GW791343 (HCl) | P2X Receptor |
GW791343 dihydrochloride (GW791343 (HCl)) is a P2X7 allosteric modulator. | |||
TP1474 | LXW7 | Integrin | |
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. LXW7 is a disulfide cyclic octa-pepti... | |||
TP2148 | LXW7 TFA (1313004-77-1 free base) | LXW7 TFA | Integrin |
LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor with an anti-inflammatory effect. LXW7 has a high binding affinity to αvβ3 integrin (IC50: 0.68 μM). It increases the phosphorylation... | |||
T15452 | GW7604 | Others | |
GW7604 is an antiestrogen and it also is the metabolite of GW5638. GW5638 is an antagonist of high-affinity estrogen receptor (ER). | |||
T75724 | LXW7 TFA | ||
LXW7 TFA, a cyclic peptide encompassing Arg-Gly-Asp (RGD), serves as an inhibitor of integrin αvβ3. It demonstrates high binding affinity towards αvβ3 integrin, evidenced by an IC50 value of 0.68 μM. Additionally, LXW7 T... | |||
T27513 | GW7845 | GW 7845,GW-7845 | |
GW7845, an L-tyrosine derivative, is a PPAR-γ agonist. | |||
T24123 | GW780056X | GW-780056-X,GW 780056 X | |
GW780056X is a selective inhibitor of cyclin-dependent kinase. GW780056X is also an inhibitor of Yes1 kinase. It is an inhibitor of binding or entry into cells for the Lassa Virus. | |||
T6526 | GW791343 trihydrochloride | GW791343 3HCl | P2X Receptor |
GW791343 trihydrochloride (GW791343 3HCl) is aHCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7. | |||
T35103 | W7477 | BRN 0626598,W 7477,W-7477,CP 14304 | |
W7477 is a biochemical. | |||
T11519 | GW768505A free base | Others | |
GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2 (pIC50: 7.81 for VEGFR2) with anti-angiogenic activity. |