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Cat No. | Product Name | Synonyms | Targets |
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T27417L | Glutathione arsenoxide hydrochloride | GSAO HCl,Glutathione arsenoxide hydrochloride(1271726-51-2 Free base) | Apoptosis , AChR |
Glutathione arsenoxide hydrochloride (Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)) is a potentially active anti-cancer molecule and inhibitor of tumour metabolism. glutathione arsenoxide hydrochloride ta... | |||
T9978 | Glutathione synthesis-IN-1 | Others | |
Glutathione synthesis-IN-1 (DC-1) is a inhibitor of glutathione synthesis[1]. | |||
TN7044 | S-(4-Hydroxybenzyl)glutathione | GluR | |
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia ela... | |||
T24807 | S-Methylglutathione | S-Methyl glutathione,Glutathione S-methyl ester,Glutathione ester | |
S-methyl glutathione is an inhibitor of methionine-containing peptide and glyoxylate. | |||
T10956 | Dansyl glutathione | DNS-glutathione | Others |
Dansyl glutathione is a capture agent used for quantitative assessment and identification of reactive metabolites. | |||
T24782 | S-Ethyl glutathione | Glutathione monoethyl ester,Glutathione ethyl ester,L-gamma-Glutamyl-S-ethyl-L-cysteinylglycine | |
S-Ethyl glutathione is the enzyme Glyoxalase 1 inhibitor. | |||
T38312 | L-Cysteine-glutathione disulfide | ||
L-Cysteine-glutathione disulfide, a glutathione derivative endogenous to mammalian cells, is comprised of the oxidized form of free glutathione tripeptide linked via a disulfide bond to L-cysteine. It has been shown to p... | |||
T27417 | Glutathione arsenoxide | GSAO | |
Glutathione arsenoxide is a hydrophilic derivative of phenylarsine oxide (PAO), a protein tyrosine phosphatase inhibitor. Glutathione arsenoxide inhibits angiogenesis and tumour growth. | |||
T68833 | Glutathione sulfinanilide | ||
Glutathione sulfinanilide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth. | |||
T70831 | Glutathione maleimide | ||
Glutathione maleimide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth. | |||
T70602 | Glutathione glycylethyl ester | ||
Glutathione glycylethyl ester is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth. | |||
T70331 | Glutathione sulfonate | ||
Glutathione sulfonate is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth. | |||
T78342 | Glutathione reductase | EC 1.6.4.2 | |
Glutathione reductase (EC 1.6.4.2) is an enzyme that ensures the availability of reduced glutathione [1]. | |||
T69992 | Glutathione sodium | ||
Glutathione sodium is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth. | |||
T36073 | S-Acetyl-L-glutathione | ||
S-Acetyl-L-glutathione is a derivative of glutathione .1 It increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency when used at a concentration of 50 μM. S-... | |||
T19930 | Nitrosoglutathione | S-Nitrosoglutathione,SNOG,Glutathione thionitrite,GSNO | RAAS , NO Synthase |
Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins. GSNO, an exogenous NO donor and substrate of rat alcohol dehydrogenase class III isoenzyme, i... | |||
T36173 | L-Glutathione, oxidized (sodium salt) | ||
Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized fo... | |||
T31949 | Glutathione amide | GASH cpd,L-gamma-Glutamyl-L-cysteinylglycinamide | |
Glutathione amide is a enzyme of a chimeric protein. | |||
T31950 | Glutathione monoisopropyl ester | YM737,YM 737,YM-737 | |
Glutathione monoisopropyl ester is a biochemical. | |||
T71441 | Glutathione palmitamide | ||
Glutathione palmitamide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth. | |||
T80056 | Glutathione Peroxidase | GSH-Px,EC 1.11.1.9 | Glutathione Peroxidase |
Glutathione Peroxidase (GSH-Px; EC 1.11.1.9), a member of the peroxidase family, catalyzes the oxidation of reduced glutathione (GSH) to oxidized glutathione (GSSG) by forming a disulfide bridge, concurrently reducing hy... | |||
T78616 | Glutathione ethyl ester | Reactive Oxygen Species | |
Glutathione ethyl ester, a cell-permeable GSH donor, enhances the in vitro production of embryos by bolstering antioxidative defense, thereby ensuring an effective GSH supply to the oocyte [1]. | |||
T34605 | Selenodiglutathione | Seleno-di-glutathione,Bis(glutathione) selenide | |
Selenodiglutathione is a primary Se metabolite conjugated with two glutathione (GSH) moieties. | |||
T68202 | Glutathione diethyl ester | ||
Glutathione diethyl ester is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth. | |||
T81234 | S-(1,2-Dicarboxyethyl)glutathione | ||
S-(1,2-Dicarboxyethyl)glutathione is a peptide known for its inhibitory effects on blood coagulation and platelet aggregation [1]. | |||
T81233 | S-(p-Nitrobenzyl)glutathione | ||
S-(p-Nitrobenzyl)glutathione acts as a competitive inhibitor of glutathionase. Rat kidney microsomes convert this compound into associated cysteine derivatives. It serves as a research tool in investigating the catabolis... | |||
T83926 | S-Geranylgeranyl-L-glutathione | GGG | |
S-Geranylgeranyl-L-glutathione acts as a ligand for the orphan G protein-coupled receptor (GPCR) P2RY8, displaying selective affinity by inducing internalization of P2RY8 in preference to the sphingosine-1-phosphate rece... | |||
T35940 | Darinaparsin | Dimethylarsinic glutathione,Darinaparsin | |
Darinaparsin is a dimethylated arsenic linked to glutathione. It is cytotoxic to DU145, LNCaP, and PC3 prostate cancer cells (IC50s = 5-10 µM) and patient-derived primary prostate cancer cells (IC50s = 2.5-20 µM)... | |||
T80098 | N,S-Bis-Fmoc-Glutathione | ||
N,S-Bis-Fmoc-Glutathione is a potent inhibitor of glyoxalase II, exhibiting a K i of 0.32 mM [1]. | |||
T37314 | JKE-1674 | GPX | |
JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4). JKE-1674 is an active metabolite of the GPX4 inhibitor ML-210. | |||
T83780 | GPX4 24 | Phospholipid Hydroperoxide Glutathione Peroxidase 24,PHGPx 24,Glutathione Peroxidase 4 24 | |
GPX4 24, a derivative of (1S,3R)-RSL3, acts as a potent inhibitor of glutathione peroxidase 4 (GPX4) through covalent binding in a concentration-dependent manner within 4T1 murine mammary carcinoma cells. This compound e... | |||
T40588 | Acifluorfen | Others | |
Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX) and induces tumors in rodent livers. It causes significant photooxidative damage to pigments a... | |||
T5340 | MPO-IN-28 | Glutathione Peroxidase | |
MPO-IN-28 is a novel potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM. | |||
T8375 | ML-210 | CID 49766530 | Ferroptosis , GPX , Glutathione Peroxidase , Ras |
ML-210 (CID 49766530) is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity | |||
T4090 | PF-06282999 | Glutathione Peroxidase | |
PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potentially useful for the treatment of cardiovascular diseases. | |||
T14379 | AZD5904 | Glutathione Peroxidase | |
AZD5904 is a potent and irreversible human Myeloperoxidase (MPO) inhibitor(IC50 of 140 nM and has similar potency in mouse and rat). | |||
T7831 | Nitecapone | Others , Transferase | |
Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver) | |||
T5481 | TRi-1 | Others | |
TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy | |||
T12189 | NBDHEX | Apoptosis , Glutathione Peroxidase , Autophagy | |
NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) . | |||
T11505 | GSTO1-IN-1 | Glutathione Peroxidase , GST | |
GSTO1-IN-1 is a potent glutathione S-transferase omega 1 inhibitor (GSTO1; IC50: 31 nM). | |||
T8970 | ML162 | Ferroptosis , GPX , Glutathione Peroxidase | |
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively) | |||
T5463 | Verdiperstat | AZD3241,AZD 3241 | Glutathione Peroxidase |
Verdiperstat (AZD 3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders. | |||
T10339 | Antitrypanosomal agent 1 | Parasite | |
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM). | |||
T38155 | N-Acetyl-D-cysteine | Reactive Oxygen Species | |
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group. | |||
T8452 | Dantrolene | Others | |
Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors. | |||
T21480 | Diethylmaleate | Maleic acid, diethyl ester,DIETHYL MALEATE | NF-κB |
Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB. | |||
T3646 | RSL3 | RSL3 1S,1S,3R-RSL3 | Ferroptosis , GPX , Glutathione Peroxidase |
RSL3 (RSL3 1S) is an inhibitor of GPX4, and inhibits system xc- that blocks GSH synthesis (IC50=100 nM). RSL3 is a VDAC-independent activator of iron death that is selective for tumor cells carrying oncogenic RAS. | |||
T4313 | Tinoridine hydrochloride | Nonflamin,Y-3642 hydrochloride | COX , Glutathione Peroxidase |
Tinoridine hydrochloride (Y-3642 hydrochloride) is a non-steroidal anti-inflammatory drug. Tinoridine hydrochloride (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxid... | |||
T5097 | Ezatiostat | TER199(free base),TLK199 | Apoptosis , Glutathione Peroxidase , GST |
Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity. | |||
T4564 | Ethacrynic acid | Edecrin,Etacrynic Acid,Hydromedin | Others , Calcium Channel , NF-κB , GST |
Ethacrynic acid (Edecrin) is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in the thick ascending limb of the loop of Henle. It also inhibits glutathione S-transferase a... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1085L | Glutathione oxidized | Bi(glutathion-S-yl),Oxidized glutathione,L-Glutathione oxidized,Glutathione disulfide,L(-)-Glutathione,GSSG | Reactive Oxygen Species , Endogenous Metabolite , Glutathione reductase |
Glutathione oxidized (L(-)-Glutathione) is a GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized. | |||
T1085 | L-Glutathione reduced | GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,Tathion | Ferroptosis , Reactive Oxygen Species , Endogenous Metabolite , Glutathione reductase |
L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is invo... | |||
T3S0012 | Coniferyl ferulate | P-gp , GST | |
Coniferyl ferulate is a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis. It shows strong inhibition of human placental GST (IC50: 0.3 μM). It also reverses multidrug resistance ... | |||
T5372 | L-SelenoMethionine | L-(+)-Selenomethionine | Apoptosis , Amino Acids and Derivatives , Endogenous Metabolite |
L-SelenoMethionine (L-(+)-Selenomethionine) is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase. | |||
T2800 | L-Theanine | Apoptosis , Others | |
L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation. | |||
TN1078 | Seneciphylline | P450 , GST | |
Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutat... | |||
T2O2721 | L-Cysteine | Thioserine,cysteine,L-(+)-Cysteine | Endogenous Metabolite |
L-Cysteine (L-(+)-Cysteine) is a non-essential sulfur-containing amino acid in humans. L-Cysteine is important for protein synthesis, detoxification, and diverse metabolic functions. Found in beta-keratin, the main prote... | |||
TJS0338 | 4-Methylesculetin | 4-Methyl-6,7-dihydroxycoumarin,Methylesculetin | Antioxidant , Glutathione Peroxidase |
4-Methylesculetin (Methylesculetin) is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities. | |||
T7995 | α-Angelica lactone | Alpha-Angelica Lactone | Others , GST |
α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization. | |||
T3S0541 | Curzerene | Apoptosis , GST | |
Curzerene, a sesquiterpene compound derived from the rhizome of Curculigo orchioides Gaertn, possesses potent anti-cancer properties. It is known to induce apoptosis in cells[1] and also suppress the expression of glutat... | |||
TN7107 | S-(2-Carboxypropyl)cysteine | Endogenous Metabolite | |
S-(2-Carboxypropyl)cysteine is a urinary metabolite of S-(2-Carboxypropyl)glutathione. | |||
T4879 | 12-Hydroxydodecanoic acid | 12-hydroxylauric acid | Others , Endogenous Metabolite |
12-Hydroxydodecanoic acid (12-hydroxylauric acid) is the substrate of the human glutathione-dependent formaldehyde dehydrogenase. | |||
T4818 | Thyminose | 2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose | Others , Endogenous Metabolite |
Thyminose (2-Deoxy-D-arabinose) induces Apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. | |||
TN2175 | Salvianolic acid F | Caspase | |
The role of our hybrid molecules, an analogue of Salvianolic acid F, in compelling the glioma cells towards apoptosis by specifically perturbing the concentration of glutathione along with caspase 6. | |||
TJS1382 | Taraxerone | Dehydrogenase | |
Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration with the concentration dep... | |||
T0507 | L-Pyroglutamic acid | pidolic acid,L-pyroglutamate,5-Oxoproline | Others , Endogenous Metabolite |
L-Pyroglutamic acid (pidolic acid), a cyclized derivative of the L-GLUTAMIC ACID, can elevate blood levels. This function may be associated with problems of GLUTATHIONE or GLUTAMINE metabolism. | |||
T5654 | Musk ketone | Others | |
Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant. | |||
T60789 | L-Cystine dihydrochloride | ||
L-Cystine dihydrochloride is a sulfur-containing precursor of glutathione (GSH) synthesis. The homeostasis of L-Cystine dihydrochloride is important for GSH functions. L-Cystine can be used as a cell culture ingredient [... | |||
T19117 | 3-Deoxyglucosone | 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose | GPX , Glucagon Receptor |
3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein amino groups to form advanced glycosylated end proteins (AGE... | |||
T3S0218 | Thonningianin A | Apoptosis , Others | |
1. Thonningianin A has anti-cancer activities.2. Thonningianin A represents a new potent glutathione S-transferase in vitro inhibitor.3. Thonningianin A has antioxidant property, involves radical scavenging, anti-superox... | |||
T11680 | Isoasatone A | P450 | |
Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity. | |||
TN5283 | L-Cysteine hydrochloride hydrate | L-Cysteine hydrochloride monohydrate | Others , Endogenous Metabolite |
L-Cysteine hydrochloride hydrate (L-Cysteine hydrochloride monohydrate) is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), taurine and gl... | |||
T2S1778 | DL-Goitrin | Goitrin | Others |
DL-Goitrin is a potent antithyroid compound found naturally in crucifers. DL-Goitrin is responsible for the induction of glutathione S-transferases. DL-Goitrin is a moderate inhibitor of purified bovine adrenal dopamine ... | |||
T2S0618 | β-Elemonic Acid | 3-oxo Tirucallic Acid,Beta-Elemonic acid,3-Oxotirucallenoic Acid,Elemadienonic Acid | Apoptosis , Reactive Oxygen Species , COX |
β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are rel... | |||
TN5538 | 6-Methoxykaempferol | Others | |
6-Methoxykaempferol is a flavonoid found in brazilian propolis. 6-Methoxykaempferol has anti-proliferative activity against cancer cells, neuroprotective effects on isolated rat brain synaptosomes and reduces glutathione... | |||
T6S0071 | Fraxinellone | HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1 | |
1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding... | |||
T2823 | Crocin | Gardenia Yellow,Alpha-Crocin | Others |
Crocin (Gardenia Yellow) is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne... | |||
TN5166 | Trans-Methylisoeugenol | Parasite , GST | |
Trans-Methylisoeugenol is a compound with insecticidal activity isolated from Acorus calamus L. It is a natural food flavor. It is a natural food flavor with anxiolytic and antidepressant properties and moderately revers... | |||
T4918 | DL-Glyceraldehyde | Glyceric aldehyde | Reductase |
DL-Glyceraldehyde (Glyceric aldehyde) is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels, ... | |||
TN4318 | Isophysalin A | IκB/IKK | |
Isophysalin A exhibits anti-inflammatory activitiy, it exhibits conjugating abilities with glutathione and also shows significant nitric oxide (NO) production inhibiting activities. | |||
T25687 | Leukotriene C4 | LTC4,Leukotriene C | |
Leukotriene C4 is the conjugation product of Leukotriene A4 and glutathione. It is the major arachidonic acid metabolite in human mast cells, macrophages, and antigen-sensitized lung tissue. It stimulates mucus secretion... | |||
TN4345 | Jacobine | Others | |
Jacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses. It was catalyzed by guinea pig hepatic glutathione-S-transferase enzymes in in vitro experiments. | |||
TN2849 | 3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid | Antifection | |
2-O-beta-d-Glucosyloxy-4-methoxybenzenepropanoic acid[3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid] exhibits glutathione S-transferase (GST) inhibitory and antifungal activities. | |||
T5S0313 | Liguiritigenin-7-O-D-apiosyl-4'-O-D-glucoside | Liquiritin apioside | Others , TNF |
Liquiritin apioside has antioxidant property by inducing glutathione (GSH) biosynthesis via the inhibition of cytokines and protected lung epithelial cells against cigarette smoke-mediated oxidative stress, might be as p... | |||
TN2006 | Odoriflavene | Others | |
Odoriflavene has antioxidant activity, and it also shows inhibition effects on the decrease of glutathione level of rat lens induced by UV irradiation. Odoriflavene shows cytotoxic activity against a SH-SY5Y cell line in... | |||
T82046 | Irisquinone | ||
Irisquinone, a natural anticancer agent, also acts as a radiation sensitizer for cancer therapies. It diminishes glutathione (GSH) levels and hampers the repair of single-strand DNA breaks [1] [2] [3]. | |||
TN3735 | Cycloart-23-ene-3,25-diol | Antifection | |
Cycloart-23-ene-3,25-diol has anti-inflammatory activity, it has protective activity against streptozotocin induced toxicity. Cycloart-23-ene-3,25-diol treatment can decrease liver malondialdehyde but increase superoxida... | |||
TN2876 | 3,4-Dihydroxy-2-methoxyxanthone | Antibacterial , Antifection | |
3,4-Dihydroxy-2-methoxyxanthone shows antibacterial, and hepatoprotective activities, it can prevent tert-butylhydroperoxide-induced lipid peroxidation and cell death in freshly isolated rat hepatocytes and is effective ... | |||
T37714 | Fuscin | ||
Fuscin is a quinonoid fungal metabolite originally isolated from O. fuscum that has diverse biological activities. It inhibits binding of the ADP/ATP translocase inhibitor atractyloside to rat liver mitochondria in an AD... | |||
T35770 | Cylindrospermopsin | ||
Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of ... | |||
T36448 | (E)-Ajoene | ||
(E)-Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities.1,2,3,4It is active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 μg/ml, respectively) and fu... | |||
T83915 | Norbixin hydrate | ||
Norbixin, a carotenoid found in B. orellana, exhibits various biological activities including binding to the peroxisome proliferator-activated receptor γ (PPARγ) with a Ki of 1.15 µM in a cell-free assay. At a dosage of ... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00539 | GSTA1 Protein, Human, Recombinant (His) | Human | HEK293 |
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) ... | |||
TMPJ-00979 | GSH-S Protein, Human, Recombinant (His) | Human | E. coli |
Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glyci... | |||
TMPY-03450 | GSTK1 Protein, Human, Recombinant | Human | E. coli |
GSTK1 gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. Glutathione S-transferases (GSTs) are a family of enzymes that catalyze a var... | |||
TMPY-03338 | GSTZ1 Protein, Human, Recombinant (His) | Human | E. coli |
GSTZ1 (Glutathione S-Transferase Zeta 1) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. GSTZ1 gene is a member of the glutathione S-transferase (GSTs) super-family which encodes mult... | |||
TMPY-00027 | GSTT2B Protein, Human, Recombinant (His) | Human | HEK293 |
GSTT2B Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 29 kDa. Accession number: P0CG29 | |||
TMPH-00073 | ADH2 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
Plays a central role in formaldehyde detoxification. | |||
TMPJ-00690 | PGDS Protein, Human, Recombinant | Human | E. coli |
Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macroph... | |||
TMPY-01554 | GSTM5 Protein, Human, Recombinant (His) | Human | E. coli |
GSTM5 Protein, Human, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 27.9 kDa. Accession number: AAH58881.1 | |||
TMPY-02223 | GSTM2 Protein, Human, Recombinant (His) | Human | E. coli |
Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-te... | |||
TMPJ-00499 | GSTP1 Protein, Human, Recombinant | Human | E. coli |
Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in deto... | |||
TMPY-02843 | GPX7 Protein, Human, Recombinant (hFc) | Human | HEK293 |
GPX7 gene contains 3 distinct gt-ag introns. Transcription produces 4 different mRNAs, 3 alternatively spliced variants, and 1 unspliced form. There are 5 validated alternative polyadenylation sites. The mRNAs appear to ... | |||
TMPH-00912 | ADH5 Protein, Human, Recombinant (GST) | Human | E. coli |
ADH5 Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPH-01711 | ABCC1 Protein, Human, Recombinant (His) | Human | E. coli |
Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs a... | |||
TMPH-01601 | Lactoylglutathione lyase/GLO1 Protein, Human, Recombinant (GST) | Human | E. coli |
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteocl... | |||
TMPY-02157 | GST Protein, Schistosoma japonicum, Recombinant | Schistosoma japonicum | Baculovirus-Insect Cells |
Genetic engineers have used glutathione S-transferase to create the GST gene fusion system. This system is used to purify and detect proteins of interest. In a GST gene fusion system, the GST sequence is incorporated int... | |||
TMPY-03120 | Prostaglandin D2 Synthase Protein, Human, Recombinant (His) | Human | HEK293 |
PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic mole... | |||
TMPH-01511 | GLO2 Protein, Human, Recombinant (GST) | Human | E. coli |
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. | |||
TMPH-01397 | LANCL1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during norma... | |||
TMPH-01296 | GPX5 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective syste... | |||
TMPY-03605 | Glutaredoxin 1/GRX1 Protein, Human, Recombinant (His) | Human | E. coli |
Glutaredoxin-1, also known as GRX1 and GLRX, belongs to theglutaredoxin family. Glutaredoxinsare smallredoxenzymes that useglutathioneas a cofactor. Glutaredoxins are oxidized by substrates, and reduced non-enzymatica... | |||
TMPH-02683 | GSTP1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). ... | |||
TMPH-01399 | GSTP1 Protein, Human, Recombinant (His) | Human | Yeast |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). ... | |||
TMPH-01398 | GSTP1 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). ... | |||
TMPY-02288 | Glyoxalase II/HAGH Protein, Human, Recombinant (His) | Human | E. coli |
HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase an... | |||
TMPH-01040 | CBR1 Protein, Human, Recombinant (His) | Human | Yeast |
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction... | |||
TMPH-02682 | GSTM3 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | |||
TMPH-01396 | GSTK1 Protein, Human, Recombinant (GST) | Human | E. coli |
Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB). | |||
TMPY-03412 | GGCT Protein, Human, Recombinant (His) | Human | E. coli |
GGCT belongs to the gamma-glutamylcyclotransferase family. It catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism. GGCT may play a significant role in ... | |||
TMPH-01039 | CBR1 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction... | |||
TMPH-03138 | GST Protein, Plasmodium falciparum, Recombinant (His) | Plasmodium falciparum | Yeast |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May also function as a storage protein or ligandin for parasitotoxic ferriprotoporphyrin IX (hemin). | |||
TMPY-03115 | GGT1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
GGT1 belongs to the gamma-glutamyltransferase protein family. Many members of this family have not yet been fully characterized and some of which may represent pseudogenes. GGT1 is composed of a heavy chain and a light c... | |||
TMPY-06971 | GGT1 Protein, Human, Recombinant (His) | Human | HEK293 |
GGT1 belongs to the gamma-glutamyltransferase protein family. Many members of this family have not yet been fully characterized and some of which may represent pseudogenes. GGT1 is composed of a heavy chain and a light c... | |||
TMPH-03443 | GPX2 Protein, S. cerevisiae, Recombinant (His & Myc) | Saccharomyces cerevisiae | E. coli |
Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress. Plays an important role in the oxidative stress-induced response in the pres... | |||
TMPH-03108 | GPX5 Protein, Pig, Recombinant (E. coli, His & Myc) | Sus scrofa (Pig) | E. coli |
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxi... | |||
TMPY-02201 | Peroxiredoxin 6 Protein, Human, Recombinant (His) | Human | E. coli |
PRDX6, a member of antioxidant protein superfamily, plays an important role in oxidative stress, catabolism of lipids and phospholipid lipisomes. Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is... | |||
TMPH-03109 | GPX5 Protein, Pig, Recombinant (His & Myc) | Sus scrofa (Pig) | Yeast |
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxi... | |||
TMPJ-00946 | TALDO1 Protein, Human, Recombinant (His) | Human | Human Cells |
Transaldolase (TALDO1) belongs to the transaldolase family of Type 1 subfamily. TALDO1 is expressed selectively in oligodendrocytes of the brain. TALDO1 is a key enzyme of the nonoxidative pentose phosphate pathway provi... | |||
TMPY-01480 | LTC4S Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Leukotriene C4 synthase, also known as LTC4 synthase, Leukotriene-C(4) synthase, and LTC4S, is a multi-pass membrane protein that belongs to the MAPEG family. LTC4S is detected in the lung, platelets, and the myelogenous... | |||
TMPJ-01142 | CDO1 Protein, Human, Recombinant (His) | Human | E. coli |
Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pan... | |||
TMPY-04022 | BOLA1 Protein, Human, Recombinant (His) | Human | E. coli |
BOLA1 is a mitochondrial protein that counterbalances the effect of L-buthionine-(S,R)-sulfoximine (BSO)-induced glutathione (GSH) depletion on the mitochondrial thiol redox potential. Furthermore, overexpression of BOLA... | |||
TMPJ-00836 | G6PD Protein, Human, Recombinant (His) | Human | Human Cells |
Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by ... | |||
TMPY-05069 | Prostaglandin D2 Synthase Protein, Rat, Recombinant (His) | Rat | HEK293 |
PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic mole... | |||
TMPY-04624 | Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic mole... | |||
TMPY-01618 | GLO1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyox... | |||
TMPY-01658 | Leukotriene A4 Hydrolase Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Leukotriene A-4 hydrolase, also known as LTA-4 hydrolase, Leukotriene A (4) hydrolase, LTA4H, and LTA4, is a cytoplasm protein that belongs to the peptidase M1 family. LTA4H hydrolyzes an epoxide moiety of leukotriene A4... | |||
TMPY-00877 | Leukotriene A4 Hydrolase Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Leukotriene A-4 hydrolase, also known as LTA-4 hydrolase, Leukotriene A (4) hydrolase, LTA4H, and LTA4, is a cytoplasm protein that belongs to the peptidase M1 family. LTA4H hydrolyzes an epoxide moiety of leukotriene A4... | |||
TMPH-01503 | Humanin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e... | |||
TMPH-01502 | Humanin Protein, Human, Recombinant (GST) | Human | E. coli |
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e... |
Cat No. | Product Name | ||
---|---|---|---|
L2900 | Oxidation-Reduction Compound Library | 1264 compounds | |
1264 small molecule compounds with pro-oxidant or anti-oxidant activity for high-throughput and high-content screening. | |||
L2550 | Glutamine Metabolism Compound Library | 565 compounds | |
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... |