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Natural Products Natural ProductsDietary Supplement
Dietary supplement-related compounds comprise of high-purity dietary supplement monomeric ingredients from the fields of food science, nutrition, and life sciences research. These compounds encompass standardised forms of vitamins, phytochemicals, amino acid derivatives, and trace elements, featuring well-defined structures and stable physicochemical properties suitable for diverse research applications. In scientific applications, these monomeric compounds serve as vital tools for investigating cellular signalling pathways, metabolic regulatory mechanisms, and oxidative stress responses. Researchers typically employ them to conduct in vitro enzyme activity assays, analyse dose-response relationships in cellular models, and perform nutritional intervention studies at the animal level. This enables the systematic elucidation of specific compounds' molecular mechanisms in chronic disease prevention, ageing process regulation, and metabolic health optimisation.
Docosahexaenoic Acid
Cited
DHA, Cervonic acid
T53696217-54-5
Docosahexaenoic Acid (DHA) is an essential omega-3 fatty acid prevalent in the brain and retina.
- $34
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CitedArachidonic acid Cited
Vevodar, Immunocytophyte, Immunocytophyt, arachidonate
T4129506-32-1
Arachidonic acid (Immunocytophyt) is a polyunsaturated omega-6 essential fatty acid that serves as a major component of biological membranes and animal phospholipids. It is synthesized from dietary linoleic acid and acts as a precursor to lipid mediators such as prostaglandins, thromboxanes, and leukotrienes. Arachidonic acid can improve cognitive responses and cardiovascular function and is commonly used to induce paw edema models.
- $39
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CitedL-Ascorbic acid Cited
Vitamin C, L-Ascorbate, L(+)-Ascorbic acid, Ascorbic acid
T092850-81-7
L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant. L-Ascorbic acid functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen. L-Ascorbic acid is used in the treatment of scurvy.
- $42
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CitedEicosapentaenoic Acid
T536810417-94-4
Eicosapentaenoic Acid is an ω-3 fatty acid and an inhibitor of fatty acid synthase (FASN). Eicosapentaenoic Acid promotes DNA demethylation in the reexpression of the tumor suppressor gene CCAAT/ enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates the RAS/ERK/C/EBPβ pathway in U937 leukemia cells through demethylation of the CpG island of H-RAS intron 1. Eicosapentaenoic Acid promotes the relaxation of vascular smooth muscle cells and vasodilation.
- $36
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Curcumin Cited
Turmeric yellow, Natural Yellow 3, Indian Saffron, Diferuloylmethane
T1516458-37-7
Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity. Curcumin has a wide range of pharmacological activities such as antitumor, anti-inflammatory and antioxidant.
AutophagyEpigenetic Reader DomainFerroptosisHDACHistone AcetyltransferaseInfluenza VirusMitophagyNrf2
- $37
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CitedBiotin Cited
Vitamin H, Vitamin B7, D-Biotin
T111658-85-5
Biotin (Vitamin H) is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.
- $31
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CitedFucoxanthin Cited
all-trans-Fucoxanthin
T76003351-86-8
Fucoxanthin (all-trans-Fucoxanthin) is a carotenoid naturally found in certain algae, serving as an accessory pigment in the chloroplasts of brown algae and most other heterokonts, which imparts a brown or olive-green color. It exhibits anti-obesity, antioxidant, anti-diabetic, anticancer, and anti-inflammatory activities.
- $30
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CitedD-Pantothenic acid
vitamin B5, pantothenate
T648079-83-4
D-Pantothenic acid (vitamin B5) is a water-soluble vitamin ubiquitously found in plants and animal tissues with an antioxidant property. D-Pantothenic acid is a component of coenzyme A (CoA) and a part of the vitamin B2 complex. D-Pantothenic acid is a growth factor and is essential for various metabolic functions, including the metabolism of carbohydrates, proteins, and fatty acids. This vitamin is also involved in the synthesis of cholesterol, lipids, neurotransmitters, steroid hormones, and hemoglobin.
- $35
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Retinol Cited
Vitamin A1, Alphalin, all-trans-Retinol
T118368-26-8
Retinol (Alphalin) and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.
- $56
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CitedNicotinamide Cited
Vitamin PP, Vitamin B3, Nicotinic acid amide, Niacinamide
T093498-92-0
Nicotinamide, a vitamin B3 derivative, is an inhibitor of SIRT1 (IC50=50-180 μM) and SIRT2 (IC50=2 μM). Nicotinamide can be used as a precursor of nicotinamide adenine dinucleotide or NAD+, which can be supplemented by dietary intake and can prevent or treat melanoglossia and pellagra.
- $32
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CitedTaurine
2-Aminoethanesulfonic acid
T0022107-35-7
Taurine (2-Aminoethanesulfonic acid) is an organic acid widely distributed in animal tissues and is one of the constituents of bile acids. Taurine is involved in a number of processes related to energy expenditure and muscle function, and can treat fatigue and muscles as well as improve immune function.
- $41
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L-Arginine Cited
L-Arg, (S)-(+)-Arginine
T3S036474-79-3
L-Arginine (L-Arg) is a substrate of endothelial nitric oxide synthase (eNOS). L-Arginine is transported to vascular smooth muscle cells via a family of cationic amino acid transporters and is metabolized to nitric oxide, polyamines, or L-proline. L-Arginine is a potent vasodilator and can be used to induce experimental acute pancreatitis.
- $31
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CitedL-Glutamic acid
glutamic acid, glutacid, 6899-05-4, (S)-Glutamic acid, (+)-L-Glutamic acid
T2A249756-86-0
L-Glutamic acid is an excitatory amino acid neurotransmitter and a Glutamic acid receptor agonist, including metabolic glutamic acid receptor (mGluR), AMPA receptor, NMDA receptor and KA receptor. L-Glutamic acid has an excitatory effect on the process of DA release from dopaminergic nerve endings. L-Glutamic acid can be used in the research of neurological diseases. L-Glutamic acid acts on ionic and metabolic Glutamic acid receptors.
- $42
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L-Glutamine Cited
L-Glutamic acid 5-amide
T0326L56-85-9
L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid that exists in large quantities in the human body and participates in many metabolic processes. L-Glutamine provides a carbon source for oxidation in certain cells.
- $29
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CitedL-Tryptophan Cited
Tryptophane, Tryptophan, L-Tryptophane, (S)-Tryptophan
T043973-22-3
L-Tryptophan (Tryptophane), an essential amino acid, is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid) and of INDOLE ALKALOIDS in plants. It can be a precursor to NIACIN, although inefficiently in mammals.
- $31
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Citedα-Linolenic acid Cited
Linolenic acid, Alpha-Linolenic Acid
T3P2904463-40-1
α-Linolenic Acid (ALA) is an essential fatty acid that cannot be synthesized by the human body and is obtained by isolating it from seed oils. α-Linolenic acid has been shown to improve memory, inhibit thrombosis, and lower blood lipids.
- $33
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CitedPyridoxine Cited
Vitamin B6, Pyridoxol, Gravidox
T097365-23-6
Pyridoxine (Vitamin B6) is the 4-methanol form of vitamin B6 and is converted to pyridoxal 5-phosphate in the body. Although pyridoxine and vitamin B6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading.
- $39
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CitedMelatonin Cited
N-Acetyl-5-methoxytryptamine, Melatonine
T165973-31-4
Melatonin (Melatonine) is a natural hormone secreted by the pineal gland that activates melatonin receptors. Melatonin is a hormone that regulates the biological clock and also has antioxidant and anti-inflammatory activities.
ApoptosisAutophagyCaMKEndogenous MetaboliteEstrogen/progestogen ReceptorGlutathione PeroxidaseMelatonin ReceptorMitophagyROR
- $31
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CitedVitamin B12
Cyanocobalamin
T104068-19-9
Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intestine. Cyanocobalamin is necessary for hematopoiesis, neural metabolism, DNA, and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 (Cobalamin) deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.
- $31
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Folic acid Cited
Vitamin M, Vitamin B9, Pteroylglutamic acid, Folate, Folacin
T006259-30-3
Folic acid is an orally active essential nutrient involved in the synthesis of DNA/RNA and the production and maintenance of new cells. It exhibits antidepressant-like effects and can reduce the risk of neural tube defects in newborns. Folate deficiency can cause megaloblastic anemia, macrocytic anemia, neural tube closure defects, tumors, and aging-related diseases. Folic acid is also commonly used in research on folate deficiency-related conditions and to induce acute kidney injury models.
- $31
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CitedNiacin Cited
Vitamin B3, Nicotinic acid
T087959-67-6
Niacin (Nicotinic acid) is a water-soluble vitamin belonging to the vitamin B family, which occurs in many animal and plant tissues, with antihyperlipidemic activity. Niacin is converted to its active form niacinamide, which is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and its phosphate form, NADP.
- $37
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Citedglycine Cited
Glycosthene, Glycolixir, Glycocoll, Aminoacetic acid, 2-Aminoacetic acid
T2O272856-40-6
glycine (2-Aminoacetic acid) is a non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
- $41
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CitedRiboflavin phosphate sodium
Vitamin B2 Phosphate Sodium Salt, riboflavin-5'-phosphate, Riboflavin 5'-phosphate sodium, FMN-Na, FMN, Flavin mononucleotide
T1331130-40-5
Riboflavin phosphate sodium (FMN) is the sodium phosphate form of riboflavin, a water-soluble and essential micronutrient that is the primary growth promoter of the naturally occurring vitamin B complex. Riboflavin phosphate sodium is converted into 2 coenzymes, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which produce energy by aiding in the metabolism of fats, carbohydrates, and proteins, and are required for red blood cell formation and respiration, antibody production, and regulation of growth and reproduction in the body.
- $33
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L-Ascorbic acid sodium salt
Vitamin C sodium salt, Sodium L-ascorbate, Sodium ascorbate, L-Ascorbic acid sodium, (+)-Sodium L-ascorbate
T6674134-03-2
L-Ascorbic acid sodium salt (Vitamin C sodium salt) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.
- $30
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