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Glucocorticoid Receptor

The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind. The GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TN3910 Ecdysone 3604-87-3 100%
Ecdysone
Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signal...
T78073 HP210 728039-52-9 98%
HP210
HP210, a selective glucocorticoid receptor modulator (SGRM), can suppress IL-1β and IL-6 mRNA expression, suggesting its utility in investigating inflammation-re...
T80652 N-Demethyl Mifepristone 104004-96-8 98%
N-Demethyl Mifepristone
N-Demethyl Mifepristone (RU 42633), an active metabolite of Mifepristone, exhibits 61% of the affinity for the glucocorticoid receptor relative to Mifepristone's...
T1614 Hydrocortisone 50-23-7 99.95%
Hydrocortisone
Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolyt...
T2526 Ciclesonide 126544-47-6 99.94%
Ciclesonide
Ciclesonide (Alvesco)(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases.
T0107 Halcinonide 3093-35-4 99.94%
Halcinonide
Halcinonide (Halciderm), a high-efficiency corticosteroid, is served as an anti-inflammatory agent used in topical preparations.
T9022 AZD9977 1850385-64-6 99.92%
AZD9977
AZD9977 is a novel, selective modulator of mineralocorticoid receptor .
T1124 Flumethasone 2135-17-3 99.91%
Flumethasone
Flumethasone (RS-2177) is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
T0977 Medrysone 2668-66-8 99.91%
Medrysone
Medrysone (6α-Methyl-11β-hydroxyprogesterone) is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone ex...
T2548 Diflorasone 2557-49-5 99.91%
Diflorasone
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by dif...
T0261 Amcinonide 51022-69-6 99.9%
Amcinonide
Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.
T0947L Dexamethasone Phosphate disodium 2392-39-4 99.88%
Dexamethasone Phosphate disodium
Dexamethasone Phosphate disodium (EGP437. Dex-Phos) is a water-soluble form of the synthetic glucocorticoid dexamethasone.
T2748 Cortodoxone 152-58-9 99.87%
Cortodoxone
Cortodoxone (11-Desoxycortisol) is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland.
T1541 Drospirenone 67392-87-4 99.85%
Drospirenone
Drospirenone (ZK 3059) is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.
T0820 Triamcinolone acetonide 76-25-5 99.84%
Triamcinolone acetonide
Triamcinolone acetonide (Azmacort) is a Corticosteroid. The mechanism of action of triamcinolone acetonide is as a Corticosteroid Hormone Receptor Agonist. It is...
T8396 Prednisone acetate 125-10-0 99.84%
Prednisone acetate
Prednisone acetate (Prednisone 21-acetate) is a glucocorticoid receptor agonist with immunomodulating properties and anti-inflammatory.
T1560 Prednisolone 50-24-8 99.83%
Prednisolone
Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
T0948L Corticosterone 50-22-6 99.82%
Corticosterone
Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involv...
T3033 Deoxycorticosterone acetate 56-47-3 99.81%
Deoxycorticosterone acetate
Deoxycorticosterone acetate (Cortexone acetate) is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of...
T0354 Canrenone 976-71-6 99.8%
Canrenone
Canrenone (SC14266) is an aldosterone antagonist with potassium-sparing diuretic activity.
Ecdysone
TN3910
Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signal...
HP210
T78073
HP210, a selective glucocorticoid receptor modulator (SGRM), can suppress IL-1β and IL-6 mRNA expression, suggesting its utility in investigating inflammation-re...
N-Demethyl Mifepristone
T80652
N-Demethyl Mifepristone (RU 42633), an active metabolite of Mifepristone, exhibits 61% of the affinity for the glucocorticoid receptor relative to Mifepristone's...
Hydrocortisone
T1614
Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolyt...
Ciclesonide
T2526
Ciclesonide (Alvesco)(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases.
Halcinonide
T0107
Halcinonide (Halciderm), a high-efficiency corticosteroid, is served as an anti-inflammatory agent used in topical preparations.
AZD9977
T9022
AZD9977 is a novel, selective modulator of mineralocorticoid receptor .
Flumethasone
T1124
Flumethasone (RS-2177) is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
Medrysone
T0977
Medrysone (6α-Methyl-11β-hydroxyprogesterone) is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone ex...
Diflorasone
T2548
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by dif...
Amcinonide
T0261
Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.
Dexamethasone Phosphate disodium
T0947L
Dexamethasone Phosphate disodium (EGP437. Dex-Phos) is a water-soluble form of the synthetic glucocorticoid dexamethasone.
Cortodoxone
T2748
Cortodoxone (11-Desoxycortisol) is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland.
Drospirenone
T1541
Drospirenone (ZK 3059) is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.
Triamcinolone acetonide
T0820
Triamcinolone acetonide (Azmacort) is a Corticosteroid. The mechanism of action of triamcinolone acetonide is as a Corticosteroid Hormone Receptor Agonist. It is...
Prednisone acetate
T8396
Prednisone acetate (Prednisone 21-acetate) is a glucocorticoid receptor agonist with immunomodulating properties and anti-inflammatory.
Prednisolone
T1560
Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
Corticosterone
T0948L
Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involv...
Deoxycorticosterone acetate
T3033
Deoxycorticosterone acetate (Cortexone acetate) is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of...
Canrenone
T0354
Canrenone (SC14266) is an aldosterone antagonist with potassium-sparing diuretic activity.
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TargetMol