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Glucocorticoid Receptor

The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind. The GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response.
Cat. No. Product name CAS No. Purity Chemical Structure
T15246 Esaxerenone 1632006-28-0 98%
Esaxerenone is a highly potent and selective non-steroidal antagonist of the mineralocorticoid receptor.
T14301 Apararenone 945966-46-1 98%
Apararenone is a novel antagonist of non-steroidal mineralocorticoid receptor, and for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis....
T1683 Actriol 547-81-9 95.35%
Actriol is always used as Glucocorticoid Receptor agonist.
T1666 Fludrocortisone acetate 514-36-3 97.6%
Fludrocortisone, a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of ...
T0208 Prednisolone disodium phosphate 125-02-0 98%
Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties.
T15389L Glucagon (1-29), bovine, human, porcine hydrochloride 28270-04-4 98%
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylatio...
T17217 Vamorolone 13209-41-1 98.04%
Vamorolone is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects...
T6580 Meprednisone 1247-42-3 98.07%
Betapar(Meprednisone) is a glucocorticoid and a methylated derivative of prednisone.
T15102 Dexamethasone palmitate 14899-36-6 98.08%
Dexamethasone palmitate is a prodrug of Dexamethasone and a glucocorticoid receptor agonist. It shows a 47-fold lower affinity for the glucocorticoid receptor th...
T0294 6α-Methylprednisolone 21-hemisuccinate sodium salt 2375-03-3 98.16%
METHYLPREDNISOLONE, a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.
T3316 Fluorometholone 426-13-1 98.21%
Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon)...
T3096 Canrenoate potassium 2181-04-6 98.28%
Potassium canrenoate is a synthetic pregnadiene derivative with anti-aldosterone activity.
T1561 Clobetasol propionate 25122-46-7 98.44%
Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expre...
T4602 Hydrocortisone hemisuccinate 2203-97-6 98.7%
Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.
T0337 Prednisolone acetate 52-21-1 98.85%
Prednisolone Acetate is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
T14377 AZD5423 1034148-04-3 98.94%
AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in su...
T16727 Relacorilant 1496510-51-0 99%
Relacorilant is a selective and orally bioavailable antagonist of glucocorticoid receptor(Ki of 7.2 nM in HepG2 TAT assay, and also shows Kis of 12, 81.2, 210 nM...
T0181 Loteprednol etabonate 82034-46-6 99%
Loteprednol Etabonate is an ophthalmic analog of the corticosteroid prednisolone with anti-inflammatory activity.
T2810 (20S)-Protopanaxatriol 34080-08-5 99%
(20S)-Protopanaxatriol(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid receptor.
T0270 Hydrocortisone 17-butyrate 13609-67-1 99.01%
Hydrocortisone Butyrate is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects.
Esaxerenone
T15246
Esaxerenone is a highly potent and selective non-steroidal antagonist of the mineralocorticoid receptor.
Apararenone
T14301
Apararenone is a novel antagonist of non-steroidal mineralocorticoid receptor, and for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis....
Actriol
T1683
Actriol is always used as Glucocorticoid Receptor agonist.
Fludrocortisone acetate
T1666
Fludrocortisone, a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of ...
Prednisolone disodium phosphate
T0208
Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties.
Glucagon (1-29), bovine, human, porcine hydrochloride
T15389L
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylatio...
Vamorolone
T17217
Vamorolone is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects...
Meprednisone
T6580
Betapar(Meprednisone) is a glucocorticoid and a methylated derivative of prednisone.
Dexamethasone palmitate
T15102
Dexamethasone palmitate is a prodrug of Dexamethasone and a glucocorticoid receptor agonist. It shows a 47-fold lower affinity for the glucocorticoid receptor th...
6α-Methylprednisolone 21-hemisuccinate sodium salt
T0294
METHYLPREDNISOLONE, a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.
Fluorometholone
T3316
Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon)...
Canrenoate potassium
T3096
Potassium canrenoate is a synthetic pregnadiene derivative with anti-aldosterone activity.
Clobetasol propionate
T1561
Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expre...
Hydrocortisone hemisuccinate
T4602
Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.
Prednisolone acetate
T0337
Prednisolone Acetate is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
AZD5423
T14377
AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in su...
Relacorilant
T16727
Relacorilant is a selective and orally bioavailable antagonist of glucocorticoid receptor(Ki of 7.2 nM in HepG2 TAT assay, and also shows Kis of 12, 81.2, 210 nM...
Loteprednol etabonate
T0181
Loteprednol Etabonate is an ophthalmic analog of the corticosteroid prednisolone with anti-inflammatory activity.
(20S)-Protopanaxatriol
T2810
(20S)-Protopanaxatriol(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid receptor.
Hydrocortisone 17-butyrate
T0270
Hydrocortisone Butyrate is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects.
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