peptide-5

Connexin43 mimetic peptide. Reduces swelling, astrogliosis, neuroinflammation and neuronal cell death following spinal cord injury ex vivo and in vivo. Exhibits analgesic effects in models of neuropathic pain. O'Carroll et al (2008) Connexin 43 mimetic peptides reduce swelling, astrogliosis and neuronal cell death after spinal cord injury. Cell.Commun.Adhes. 15 27 PMID:18649176 |Mao et al (2017) Characterisation of Peptide5 systemic administration for treating traumatic spinal cord injured rats. Exp.Brain.Res. 235 3033 PMID:28725925 |Kim et al (2017) Characterising the mode of action of extracellular Connexin43 channel mimetic peptides in an in vitro ischemia injury model. Biochem.Biophys.Acta. 1861 68 PMID:27816754 |Tonkin et al (2017) Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice. Exp.Neurol. 300 1 PMID:29055716

Peptide5 acetate reduces animal swelling, astrogliosis, and neuronal cell death after spinal cord injury. Peptide5 acetate significantly reduces the degree of spinal cord injury (SCI) in a rodent ex vivo model.

Peptide5 TFA, a connexin 43 mimetic peptide, mitigates swelling, astrogliosis, and neuronal cell death in animal models of spinal cord injury, and suppresses the NLRP3 inflammasome, functioning as an anti-inflammatory agent (1) (2) (3).

Palmitoyl Dipeptide-5 Acetate is a peptide that is a cosmetic ingredient that improves skin quality and prevents skin aging.

Palmitoyl tripeptide-5, a bioactive peptide, is widely used in cosmetics for its anti-aging properties [1].

Palmitoyl Dipeptide-5 Diaminohydroxybutyrate is a bioactive peptide recognized for its anti-aging properties and is commonly utilized as an ingredient in cosmetics [1].

Palmitoyl tripeptide-5 biTFA is a bioactive peptide with anti-aging properties, reported for use as a cosmetic ingredient.

Palmitoyl dipeptide-7, a bioactive peptide renowned for its anti-aging properties, is utilized as an ingredient in cosmetic formulations.

Acetyl Tetrapeptide-5 acetate helps reduce eye puffiness, improve skin elasticity as well as overall smoothness.

Tetrapeptide-5 is a humectant or hydroscopic moisturizer.

Delmitide, a TNF-alpha production inhibitor, is used potentially for the treatment of Crohn's disease and ulcerative colitis.

H-Ser-Phe-Leu-Leu-Arg-OH, also known as Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), is utilized in coronary heart disease (CHD) research.

Peptide 5e, an antimicrobial peptide, exhibits inhibitory activity against E. coli, S. aureus, and C. albicans with respective minimum inhibitory concentration (MIC) values of 30, 5, and 25 μg/mL [1].

Peptide 5g, an antimicrobial peptide, inhibits E. coli, S. aureus, and C. albicans, exhibiting minimum inhibitory concentration (MIC) values of 30, 10, and 12.5 μg/mL, respectively [1].

Peptide 5f, sourced from wasp venom, exhibits antimicrobial properties effective against both bacterial and fungal pathogens, while demonstrating minimal hemolytic activity on human red blood cells [1].

Hemoregulatory peptide 5b is a synthetic analog of granulocyte chalone which initially identified in extracts of rodent bone marrow and human leukocytes. Monomer inhibits both formations of GM-CFC colonies and cytotoxic drug-induced recruitment of murine

Fmoc-Lys(Tfa)-OH is a peptide, a lysine derivative with an Fmoc protective group on the α-amino group, widely used in biochemical experiments and drug synthesis research.

P-113 acetate is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5, shows good safety and efficacy profiles in gingivitis and human immunodeficiency virus (HIV) patients with oral candidiasis.

C-Type Natriuretic Peptide (CNP) (1-22), human acetate is an agonist of natriuretic peptide receptor B (NPR-B), an endothelial-derived relaxant and growth inhibitory factor. C-Type Natriuretic Peptide (CNP) (1-22), human acetate inhibits cAMP synthesis stimulated by histamine and 5-HT or directly by Forskolin.

IRBP acetate(211426-18-5 free base) (Interphotoreceptor Retinoid Binding Protein Fragment IRBP) is a 20-residue peptide, which is a major pathogenic epitope. It exists in the first homologous repeat of interstitial visual pigment Binding Protein peptide (IRBP 161-180) and can induce post-uveitis (EAU).

Autocamtide 2 TFA is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). Autocamtide 2 TFA can be used in the CaMKII activity assay.

N-Acetyl-α-Endorphin acetate is an acetylated α-Endorphin at N-terminal. α-Endorphin is an endogenous opioid peptide.

Mini Gastrin I, human acetate is a shorter version of human gastrin, consists of amino acids 5-17 of the parent peptide.

Lyn peptide inhibitor acetate is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors. Lyn peptide inhibitor can be used for study of asthma, allergic, and other eosinophilic disorders.