Search Result

Search Results for " osteoarthritis "

Targets

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T2553	Etofenamate		COX
	Etofenamate is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.		COX
T16124	MMP13-IN-3		MMP
	MMP13-IN-3 is >1000 selective over other MMPs. MMP13-IN-3 is an effective, selective, and orally active MMP-13 inhibitor (IC50=1 nM) for the potential treatment of osteoarthritis.		MMP
T0291	Flurbiprofen	dl-Flurbiprofen	Apoptosis , COX , MRP
	Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.		Apoptosis , COX , MRP
T1748	Kartogenin	KGN	TGF-beta/Smad
	Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.		TGF-beta/Smad
T9977	SGK1-IN-4		SGK
	SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.		SGK
T1421	Aceclofenac	Preservex,Airtal	COX
	Aceclofenac (Preservex) is a non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties.		COX
T4561	Tiaprofenic acid	Tiaprofensaeure,Acido tiaprofenico,Surgam	Others , COX
	Tiaprofenic acid (Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.		Others , COX
T9711	OGT-IN-2		Others
	OGT-IN-2 is a potent O-GlcNAc transferase (OGT) inhibitor. OGT-IN-2 inhibits sOGT and ncOGT with IC50 values of 30 μM and 53 μM, respectively[1]. OGT-IN-2 can be used for the research of articular diseases[1].		Others
T0859	Fenbufen	CL-82204,Lederfen	ATPase , Caspase , COX
	Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractur...		ATPase , Caspase , COX
T4552	Fursultiamine	Diteftin,Judolor,Alinamin F	Others
	Fursultiamine (Alinamin F) is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency.		Others
T6574	Lumiracoxib	Prexige,COX-189	COX
	Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.		COX
T1780	Parecoxib	SC 69124,Vorth-P,Valus-P	COX
	Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.		COX
T5099	Gefapixant	RO 4926219,AF219,MK-7264	P2X Receptor
	Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.		P2X Receptor
T28394	PG-116800	PG-530742,PGE-7113313,PGE 7113313,PG 530742	MMP
	PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.		MMP
T1109	(Z)-Capsaicin	Zucapsaicin,Civamide,cis-Capsaicin	TRP/TRPV Channel , HSV
	(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.(Z)-Capsaicin is a synthetic cis isomer of natural capsaicin that has shown therapeutic efficacy in pain ac...		TRP/TRPV Channel , HSV
T77502	Wnt pathway inhibitor 3		Wnt/beta-catenin , Adenylyl cyclase
	Wnt pathway inhibitor 3 is a potent AC1 inhibitor with an IC50 value of 45 nM.Wnt pathway inhibitor 3 has antiproliferative activity and can be used in studies to ameliorate osteoarthritis in a mouse model of experimenta...		Wnt/beta-catenin , Adenylyl cyclase
T15358	Funapide	TV 45070,XEN402	Sodium Channel
	Funapide (TV 45070) is a potent Sodium Channel Nav1.7 inhibitor with potential anti-inflammatory activity for the treatment of erythema gangrenosum, musculoskeletal pain, knee osteoarthritis, and postherpetic nerves.		Sodium Channel
T1586	Tenoxicam	Ro-12-0068,Tenoxicamum,Mobiflex,Tilcotil	COX
	Tenoxicam (Tilcotil), an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.		COX
T35859	Aldumastat	GLPG1972,S201086,G504572	Others
	Aldumastat (GLPG1972) is a highly potent, specific and orally active inhibitor of ADAMTS-5.Aldumastat is used for the study of osteoarthritis of the knee.		Others
T27312	Fentiazac	Donorest,Flogene,BR-700	Others
	Fentiazac（BR-700） is an orally active nonsteroidal alkanoic acid derivative with significant analgesic, anti-inflammatory, and antipyretic activity.Fentiazac is used in the study of inflammatory diseases such as rheumato...		Others
T77092	Nadecnemab	REGN-5069	Others
	Nadecnemab is an IGG4-κantibody targeting GFRA3, a receptor of the glial cell-derived neurotrophic factor family. Nadecnemab can be used for knee osteoarthritis and neurological disorders.		Others
T29663	ADL-5747	ADL-5747 (free base),ADL5747,ADL-5747 free base	Opioid Receptor
	ADL-5747 (ADL-5747 (free base)) (free base) is a delta opioid receptor agonist used in the treatment of neurological disorders, skin and musculoskeletal disorders, and may be used in the study of postherpetic neuralgia, ...		Opioid Receptor
T67805	Oxepinac
	oxepinac is an effective and well-tolerated compound for the treatment of painful osteoarthritis. oxepinac has no teratogenic effect on mouse and rabbit fetuses in animal experiments.
T14283	Amyloid P-IN-1		Beta Amyloid
	amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, and type 2 diabetes mellitus.		Beta Amyloid
T0219	Valdecoxib	SC 65872	COX
	Valdecoxib (SC 65872) is a prescription drug used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is classified as a nonsteroidal anti-inflammatory drug, or N...		COX
T78169	Enpp-1-IN-16		PDE
	Enpp-1-IN-16 is an inhibitor targeting ENPP1 with potential anti-cancer activity.Enpp-1-IN-16 can be used to study insulin resistance in relation to type II diabetes mellitus and various ENPP1-mediated diseases in the ch...		PDE
T14978	CL-82198		MMP
	CL-82198, a selective MMP-13 inhibitor, serves as a pharmacological intervention to halt the progression of osteoarthritis (OA). Its mechanism of action involves binding to the S1’ pocket of MMP-13, ensuring its selectiv...		MMP
T6568	Licofelone	ML-3000	Apoptosis , Lipoxygenase , COX
	Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory. Inhibition of 5-LOX may reduce the gastrointestinal toxicity ass...		Apoptosis , Lipoxygenase , COX
T7724	Tepoxalin	RWJ-20485,RWJ20485,ORF20485,ORF-20485,RWJ 20485,ORF 20485	Lipoxygenase , COX
	Tepoxalin (RWJ 20485) is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis. Tepoxalin inhibits COX-1, COX-2, and 5-LOX. Tepoxalin is a potent inhibitor of sheep seminal vesicle cyclooxyge...		Lipoxygenase , COX
T8785	HALOFUGINONE LACTATE		DNA/RNA Synthesis , TGF-beta/Smad
	HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner ...		DNA/RNA Synthesis , TGF-beta/Smad
T1641	Strontium ranelate	Distrontium renelate,S12911	Calcium Channel , CaSR
	Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both in...		Calcium Channel , CaSR
T28032	MF266-1	MF 266-1,MF-266-1
	MF266-1, a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of osteoarthritis and rheumatoid.
T68444	Dircin
	Dircin is an anti-inflammatory agent, prescribed for osteoarthritis and chronic inflammatory arthritis. It works by inhibiting interleukin-1.
T27233	Enflicoxib	E 6087,E6087,E-6087
	E-6087 is a cyclooxygenase 2 (COX-2) inhibitor potentially for the treatment of osteoarthritis and pain.
T39047	DDR2-IN-1	DDR2-IN-1
	DDR2-IN-1 (Compound 129) is recognized as a highly effective DDR2 inhibitor, displaying an IC50 value of 26 nM. It is a suitable choice for conducting osteoarthritis research.
T29084	V116517	V-116517,V 116517
	V-116517, a TRPV1 antagonist, is used potentially for the treatment of severe pain due to osteoarthritis and chronic pain due postherpetic neuralgia (PHN).
T26563	Adavivint HCl (1467093-03-3 free base)	SM-04690,Adavivint HCl,Adavivint,SM04690,SM 04690
	Adavivint, also known as SM04690, is a small-molecule inhibitor of the Wnt pathway which is being investigated as a potential disease modifying agent for the treatment of osteoarthritis of the knee
T17027	Tedalinab	GRC-10693	Cannabinoid Receptor
	Tedalinab is an effective and selective cannabinoid receptor 2 agonist. Tedalinab has the potential for neuropathic pain and osteoarthritis treatment. Tedalinab has >4700-fold functional selectivity for CB2 over CB1.		Cannabinoid Receptor
T16504	PF-4693627		Prostaglandin Receptor
	PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM). It is used for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA).		Prostaglandin Receptor
T14352	Autotaxin-IN-1		PDE
	Autotaxin-IN-1 is a potent autotaxin inhibitor, which has favorable potency (IC50=2.2 nM), PK properties, and a robust PK/PD relationship and it is used in treatment of osteoarthritis pain[1].		PDE
T30939	Cindunistat HCl maleate	PHA 728669F,SD 6010,PHA-728669F,SD6010 PF-00572986,SD-6010,PHA728669F
	Cindunistat( PHA-728669F, PF-00572986, PHA-84250, SD-6010, and SC-084250) is a potent and oral selective iNOS inhibitor which is expected to be used in patients with symptomatic osteoarthritis of the knee.
T16570	Pralnacasan	VX-740,HMR 3480	Others
	Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM). Pralnacasan has the potential ...		Others
T0184L	Fenoprofen	Nalgesic,Fenoprofen Calcium,Nalfon
	Fenoprofen is a non-steroidal anti-inflammatory drug used to relieve symptoms of rheumatoid arthritis, osteoarthritis, and mild to moderate pain. It can block the enzyme that produces prostaglandin (cyclooxygenase), resu...
T26531	ABT-963	ABT963
	ABT-963 is a cyclooxygenase 2 (COX-2) inhibitor potentially for the treatment of osteoarthritis and pain. ABT-963 has excellent selectivity in human whole blood, high oral anti-inflammatory potency in vivo, and gastric s...
T76077	MMP-13 Substrate
	MMP-13 Substrate, a compound utilized in osteoarthritis (OA) research [1], functions as a substrate for MMP-13.
T38595	EP4 receptor antagonist 3	EP4 receptor antagonist 3
	EP4 receptor antagonist 3 is a highly potent and specific inhibitor of the EP4 receptor. It is intended for research purposes in studying EP4 receptor-mediated diseases such as acute and chronic pain, osteoarthritis, rhe...
T72868	ADAMTS-5-IN-2
	ADAMTS-5-IN-2 is a potent inhibitor of ADAMTS-5, exhibiting an IC50 of 0.71 µM, and holds potential for osteoarthritis research.
T39000	Zaloglanstat	GRC-27864,ISC-27864
	Zaloglanstat (ISC-27864) is a potent inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1). It is utilized in the research of various conditions, including asthma, osteoarthritis, rheumatoid arthritis, acute or ch...
T68563	Piroxicam olamine
	Piroxicam olamine is a cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmeno...
T16291	NF157		COX
	NF157 significantly decreases the expression of metalloproteinase (MMP)-3, MMP-13, which can be used in the treatment of osteoarthritis (OA). NF157 is a highly selective nanomolar P2Y11 antagonist (pKi: 7.35). The IC50s ...		COX

Compounds

Synonym: dl-Flurbiprofen

Target: Apoptosis, COX, MRP

Kartogenin

T1748

Synonym: KGN

Target: TGF-beta/Smad

Synonym: Preservex,Airtal

Target: COX

Tiaprofenic acid

T4561

Synonym: Tiaprofensaeure,Acido tiaprofenico,Surgam

Synonym: CL-82204,Lederfen

Target: ATPase, Caspase, COX

Fursultiamine

T4552

Synonym: Diteftin,Judolor,Alinamin F

Target: Others

Lumiracoxib

T6574

Synonym: Prexige,COX-189

Target: COX

Parecoxib

T1780

Synonym: SC 69124,Vorth-P,Valus-P

Target: COX

Gefapixant

T5099

Synonym: RO 4926219,AF219,MK-7264

Target: P2X Receptor

PG-116800

T28394

Synonym: PG-530742,PGE-7113313,PGE 7113313,PG 530742

Target: MMP

(Z)-Capsaicin

T1109

Synonym: Zucapsaicin,Civamide,cis-Capsaicin

Target: TRP/TRPV Channel, HSV

Wnt pathway inhibitor 3

T77502

Synonym:

Target: Wnt/beta-catenin, Adenylyl cyclase

Funapide

T15358

Synonym: TV 45070,XEN402

Target: Sodium Channel

Tenoxicam

T1586

Synonym: Ro-12-0068,Tenoxicamum,Mobiflex,Tilcotil

Target: COX

Aldumastat

T35859

Synonym: GLPG1972,S201086,G504572

Target: Others

Fentiazac

T27312

Synonym: Donorest,Flogene,BR-700

Synonym: ADL-5747 (free base),ADL5747,ADL-5747 free base

Target: Opioid Receptor

Target: Apoptosis, Lipoxygenase, COX

Tepoxalin

T7724

Synonym: RWJ-20485,RWJ20485,ORF20485,ORF-20485,RWJ 20485,ORF 20485

Target: Lipoxygenase, COX

HALOFUGINONE LACTATE

T8785

Synonym:

Target: DNA/RNA Synthesis, TGF-beta/Smad

Strontium ranelate

T1641

Synonym: Distrontium renelate,S12911

Target: Calcium Channel, CaSR

MF266-1

T28032

Synonym: MF 266-1,MF-266-1

Synonym: E 6087,E6087,E-6087

Synonym: V-116517,V 116517

Target:

Adavivint HCl (1467093-03-3 free base)

T26563

Synonym: SM-04690,Adavivint HCl,Adavivint,SM04690,SM 04690

Target: Cannabinoid Receptor

PF-4693627

T16504

Synonym:

Target: Prostaglandin Receptor

Cindunistat HCl maleate

T30939

Synonym: PHA 728669F,SD 6010,PHA-728669F,SD6010 PF-00572986,SD-6010,PHA728669F

Target:

Pralnacasan

T16570

Synonym: VX-740,HMR 3480

Target: Others

Fenoprofen

T0184L

Synonym: Nalgesic,Fenoprofen Calcium,Nalfon

EP4 receptor antagonist 3

T38595

Synonym: EP4 receptor antagonist 3

Synonym: GRC-27864,ISC-27864

Cat No.	Product Name	Synonyms	Targets
T5689	20-DEOXYINGENOL		Others , Autophagy
	20-DEOXYINGENOL is a natual product.		Others , Autophagy
T3803	Specnuezhenide	Nuzhenide,Nuezhenide	Others , NF-κB , Wnt/beta-catenin
	Specnuezhenide (Nuezhenide) significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.Nuezhenide is the main inhibitory compound of fruits, it shows a clear inhibitory effect t...		Others , NF-κB , Wnt/beta-catenin
T5029	Oxaceprol	N-Acetyl-L-hydroxyproline	Others
	Oxaceprol (N-Acetyl-L-hydroxyproline) is an established therapeutic agent for osteoarthritis.		Others
T6S0117	Avicularin	Fenicularin	ERK
	Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX...		ERK
T6856	Halofuginone	Tempostatin,empostatin,RU-19110	Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
	Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
T3524	Halofuginone hydrobromide	Tempostatin,RU-19110 (hydrobromide),Stenorol	Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
	Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
T7475	S-Adenosyl-L-methionine	AdoMet,Ademetionine,SAMe,S-Adenosyl methionine	Others , Endogenous Metabolite
	S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.		Others , Endogenous Metabolite
T2941	Glucosamine hydrochloride	Chitosamine hydrochloride,2-Amino-2-deoxy-glucose HCl,Chitosamine HCl,D-(+)-Glucosamine hydrochloride	Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , Endogenous Metabolite , Autophagy
	Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.
T4S2157	Campesterol	(24R)-5-Ergosten-3β-ol	Endogenous Metabolite
	Campesterol ((24R)-5-Ergosten-3β-ol) is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti-inflammatory e...		Endogenous Metabolite
T1273	Diacerein	Diacerhein,Fisiodar,Diacetylrhein	IL Receptor , Interleukin
	Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including sevre ...		IL Receptor , Interleukin
T3388	Calycosin-7-O-β-D-glucoside	calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside	MMP , Reactive Oxygen Species
	Calycosin-7-O-β-D-glucoside (calycosin-7-O-beta-D-glucopyranoside) possesses a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity. Calycosin 7-O-β-D-glucoside has antimicrobial activity. Calycos...		MMP , Reactive Oxygen Species
T4447	S-(5'-Adenosyl)-L-methionine tosylate	SAMe,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt	Others
	S-(5'-Adenosyl)-L-methionine tosylate (SAMe) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases [1]. S-(5'-Adenosyl)-L-methioni...		Others
T12576	Pterosin B		Others
	Pterosin B is an salt-inducible kinase 3 (Sik3) signaling inhibitor. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis by inhibiting Sik3.		Others
T30048	Anemonin (6CI)	Pulsatilla camphor,Anemonin,Anemone camphor
	Anemonin is a furanone dimer found in the Buttercup (Ranunculaceae) family. Anemonin has been shown to regulate tyrosinase-related proteins and mRNA in human melanocytes and may be useful in attenuting osteoarthritis pro...
T4116	S-Adenosyl-DL-Methionine	Ademetionine,S-ADENOSYL-L-METHIONINE	Others
	S-Adenosyl-DL-Methionine (Ademetionine) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases. SAM reportedly ameliorates depressi...		Others
T78468	Yohimbic acid hydrate
	Yohimbic acid hydrate, an amphoteric demethylated derivative of Yohimbine, exhibits vasodilatory properties and is utilized in osteoarthritis (OA) research [1] [2] [3].

Natural Products

20-DEOXYINGENOL

T5689

Synonym:

Target: Others, Autophagy

Specnuezhenide

T3803

Synonym: Nuzhenide,Nuezhenide

Target: Others, NF-κB, Wnt/beta-catenin

Oxaceprol

T5029

Synonym: N-Acetyl-L-hydroxyproline

Synonym: Tempostatin,empostatin,RU-19110

Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Halofuginone hydrobromide

T3524

Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol

Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

S-Adenosyl-L-methionine

T7475

Synonym: AdoMet,Ademetionine,SAMe,S-Adenosyl methionine

Target: Others, Endogenous Metabolite

Glucosamine hydrochloride

T2941

Synonym: Chitosamine hydrochloride,2-Amino-2-deoxy-glucose HCl,Chitosamine HCl,D-(+)-Glucosamine hydrochloride

Target: Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, Autophagy

Campesterol

T4S2157

Synonym: (24R)-5-Ergosten-3β-ol

Target: Endogenous Metabolite

Diacerein

T1273

Synonym: Diacerhein,Fisiodar,Diacetylrhein

Target: IL Receptor, Interleukin

Calycosin-7-O-β-D-glucoside

T3388

Synonym: calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside

Target: MMP, Reactive Oxygen Species

S-(5'-Adenosyl)-L-methionine tosylate

T4447

Synonym: SAMe,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt

Synonym: Pulsatilla camphor,Anemonin,Anemone camphor

Target:

S-Adenosyl-DL-Methionine

T4116

Synonym: Ademetionine,S-ADENOSYL-L-METHIONINE

Target: Others

Yohimbic acid hydrate

T78468

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02500	YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC c...
TMPY-01304	YKL-40/CHI3L1 Protein, Human, Recombinant (His)	Human	HEK293
	Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC c...
TMPJ-00249	TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated	Human	Human Cells
	Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPK-00019	B2M/beta 2-Microglobulin Protein, Human, Recombinant (hFc)	Human	HEK293
	To assess whether beta-2 microglobulin (B2M) has effects on articular chondrocytes that would implicate B2M involvement in osteoarthritis (OA) pathogenesis.The average B2M level in OA synovial fluid is significantly high...
TMPH-01051	CILP Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligan...
TMPY-03384	CALM2 Protein, Human, Recombinant (His)	Human	E. coli
	Calmodulin 2, also known as CALM2, is a calmodulin. Calmodulin 2 mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). It is involved in a genetic pathway that regulates the centro...
TMPY-03847	FRZB Protein, Human, Recombinant (His)	Human	HEK293
	FRZB also known as sFRP-3, is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. FRZB is widely expressed in adult mammalian tissues. In t...
TMPJ-00966	GDF-5 Protein, Human, Recombinant	Human	E. coli
	Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor...
TMPY-01860	Collagen II/COL2A1 Protein, Human, Recombinant (aa 1242-1487, His)	Human	HEK293
	COL2A1 is the alpha-1 chain of type II collagen which is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this protein are associated with achondrogenesis, chondrodysplasia, early o...
TMPJ-01235	B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
	β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecule...
TMPJ-01236	B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (aa 21-119, His)	Cynomolgus	Human Cells
	β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecule...
TMPY-00433	CXCL1 Protein, Mouse, Recombinant	Mouse	E. coli
	The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu...
TMPY-00008	CXCL1 Protein, Rat, Recombinant	Rat	E. coli
	The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu...
TMPY-02868	CXCL1 Protein, Human, Recombinant	Human	E. coli
	The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu...
TMPY-02180	CXCL1 Protein, Human, Recombinant (His & NusA)	Human	E. coli
	The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu...
TMPY-02026	CXCL1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	The Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimu...

YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)

TMPY-02500

Species: Mouse

Expression System: HEK293

YKL-40/CHI3L1 Protein, Human, Recombinant (His)

TMPY-01304

Species: Human

Expression System: HEK293

TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated

TMPJ-00249

Species: Human

Expression System: Human Cells

B2M/beta 2-Microglobulin Protein, Human, Recombinant (hFc)

TMPK-00019

Species: Human

Expression System: HEK293

CILP Protein, Human, Recombinant (His & Myc)

TMPH-01051

Species: Human

Expression System: Baculovirus

CALM2 Protein, Human, Recombinant (His)

TMPY-03384

Species: Human

Expression System: E. coli

FRZB Protein, Human, Recombinant (His)

TMPY-03847

Species: Human

Expression System: HEK293

GDF-5 Protein, Human, Recombinant

TMPJ-00966

Species: Human

Expression System: E. coli

Collagen II/COL2A1 Protein, Human, Recombinant (aa 1242-1487, His)

TMPY-01860

Species: Human

Expression System: HEK293

B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (hFc)

TMPJ-01235

Species: Cynomolgus

Expression System: Human Cells

B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (aa 21-119, His)

TMPJ-01236

Species: Cynomolgus

Expression System: Human Cells

CXCL1 Protein, Mouse, Recombinant

TMPY-00433

Species: Mouse

Expression System: E. coli

CXCL1 Protein, Rat, Recombinant

TMPY-00008

Species: Rat

Expression System: E. coli

CXCL1 Protein, Human, Recombinant

TMPY-02868

Species: Human

Expression System: E. coli

CXCL1 Protein, Human, Recombinant (His & NusA)

TMPY-02180

Species: Human

Expression System: E. coli

CXCL1 Protein, Human, Recombinant (His & SUMO)

TMPY-02026

Species: Human

Expression System: E. coli

Cat No.	Product Name
L4710	Nonsteroidal Anti-Inflammatory Compound Library		530 compounds
	530 non-steroidal anti-inflammatory compounds for high-throughput and high-content screening.

Libraries

Nonsteroidal Anti-Inflammatory Compound Library

L4710

Compounds: 530