c3a

Complement C3a Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 KDa and the accession number is P01024.

Complement C3a Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 KDa and the accession number is P01027.

Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 186.43 kDa and the accession number is P01024.

Expression system: E. coli
Length: 1-199, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-121, Full Length
Activity: Not Tested

C-type lectin domain family 3 member A (CLEC3A) is a poorly characterized protein belonging to the superfamily of C-type lectins. Elevated CLEC3A expression may correlate with breast IDC metastatic potential and indicated a poor prognosis in breast IDC. CLEC3A knockdown inhibited BC cell growth and metastasis might be through suppressing PI3K AKT signaling activity. That CLEC3A is a promising therapeutic target for BC in the future. Matrilysin (MMP-7) plays important roles in tumor progression. Previous studies have suggested that MMP-7 binds to tumor cell surface and promotes their metastatic potential. C-type lectin domain family 3 member A (CLEC3A) as a membrane-bound substrate of MMP-7. CLEC3A binds to heparan sulfate proteoglycans on cell surface, leading to the enhancement of cell adhesion to integrin ligands on ECM. It can be speculated that the cleavage of CLEC3A by MMP-7 weakens the stable adhesion of tumor cells to the matrix and promotes their migration in tumor microenvironments.

APOBEC3A Protein, Human, Recombinant (His) is expressed in Yeast. The accession number is P31941.