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Search Result

Search Results for " dub "

Targets

DUB

Libraries

Ubiquitination Compound Library
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Compounds

Cat No. Product Name
T11111 DUB-IN-2 DUB
Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.
T11110 DUB-IN-1 DUB
DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific protease (USPs).
T11112 DUB-IN-3 DUB
DUB-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c. The IC50 for USP8 is 0...
T2005 Dubermatinib TP0903 TAM Receptor , Apoptosis
TP-0903 is a potent and selective Axl kinase inhibitor.
T18362 Vc-seco-DUBA Others
Vc-seco-DUBA is a drug-linker conjugate for ADC with potent antitumor activity by using DUBA (DNA alkylating agent), lin...
T77189 Sudubrilimab
Sudubrilimab (HS636) is an Ig G1-kappa monoclonal antibody against PDL1 . Sudubrilimab is fused at the C terminus of the...
T39213 Seco-DUBA hydrochloride
Seco-DUBA hydrochloride is a toxin for ADC drug SYD985.
T38611 Seco-DUBA
Seco-DUBA, a duocarmycin (DUBA) prodrug, possess two hydroxyl groups suitable for antibody coupling through a linker. Th...
T4067 VLX1570 DUB
VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM. It has potent inh...
T14852 C527 DUB
C527 is a is a pan DUB enzyme inhibitor. Which has a high potency for the USP1/UAF1 complex (IC50=0.88 μM).
T6300 Degrasyn WP1130 JAK , Apoptosis , Bcr-Abl , Autophagy , DUB
Degrasyn (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/A...
T11485 GSK2643943A DUB
GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC 50 of 160 nM for USP20/Ub-Rho. GSK2643943A has anti...
T6697 TCID UCH-L3 Inhibitor DUB
TCID(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.
T1862 PR-619 PR 619,2,6-Diamino-3,5-dithiocyanopyridine DUB , Apoptosis , Autophagy
PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs).
T11209 EOAI3402143 DUB
EOAI3402143 is a deubiquitinase (DUB) inhibitor, which inhibits dose-dependently inhibits  Usp5/Usp24 andUsp9x.
T73461 BAY-805
BAY-805 is a selective inhibitor of ubiquitin-specific protease USP21 . BAY-805 has high selectivity for deubiquitinatin...
T69690 XL-188
XL-188 is a highly potent and selective inhibitor of USP7. XL188 inhibited USP7 catalytic domain and full-length enzyme...
DUB-IN-2
T11111
synonym:
Target:
DUB-IN-1
T11110
synonym:
Target:
DUB-IN-3
T11112
synonym:
Target:
Dubermatinib
T2005
synonym: TP0903
Target:
Vc-seco-DUBA
T18362
synonym:
Target:
Sudubrilimab
T77189
synonym:
Target:
Seco-DUBA hydrochloride
T39213
synonym:
Target:
Seco-DUBA
T38611
synonym:
Target:
VLX1570
T4067
synonym:
Target:
C527
T14852
synonym:
Target:
Degrasyn
T6300
synonym: WP1130
Target:
GSK2643943A
T11485
synonym:
Target:
TCID
T6697
synonym: UCH-L3 Inhibitor
Target:
PR-619
T1862
synonym: PR 619,2,6-Diamino-3,5-dithiocyanopyridine
Target:
EOAI3402143
T11209
synonym:
Target:
BAY-805
T73461
synonym:
Target:
XL-188
T69690
synonym:
Target:
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