Controlling

Isoprothiolane is a foliar spray fungicide with eradicant and protectant activities against fungal diseases of rice plant caused by Pyvioutavia oryzae Cav.

Thermospermine is a structural isomer of spermine that plays a role in inhibiting xylem differentiation and can enhance the translation of SAC51 and SACL1 in Arabidopsis thaliana. Thermospermine is also used in studies as a plant growth regulator and for controlling wood biomass production.

Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid metabolism.

GSK2324 is a potent FXR agonist for the treatment of NAFLD by controlling hepatic lipids through reduced uptake and selective reduction of fatty acid synthesis.

Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated as a homodimer into the nucleus, where transcription activation via glucocorticoid response elements within glucocorticoid-responsive genes occur. This agent induces transcription of genes coding for anti-inflammatory proteins, including lipocortin-1, interleukin-10, interleukin-1 receptor antagonist and neutral endopeptidase. Increased synthesis of lipocortin-1 has an inhibitory effect on phospholipase A2, which in turn inhibits the release of arachidonic acid, thereby controlling the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.

Clobetasol propionate (CGP9555) exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Clobetasol Propionate is the propionate salt form of clobetasol, a topical synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. Specifically, clobetasol propionate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from membrane phospholipids by phospholipase A2.

Bupirimate (Nimrod), an active ingredient in plant protection products, is commonly used as a systemic fungicide and finds applications in controlling powdery mildew in roses, apple plantations. It belongs to the family of pyrimidines.

λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group. It is employed across various applications for controlling a wide array of pests. As a neurotoxin, λ-Cyhalothrin acts on sodium channels in neuron membranes within the central nervous system.

Magnesium sulfate is the preferred anticonvulsant for preventing and controlling eclamptic seizures. Additionally, it is extensively utilized as a tocolytic agent.

(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a potent inhibitor of ATP citrate lyase, an enzyme that catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA.

Chromafenozide (ANS118) (ANS118) is a lepidopteran insecticide with the effect of controlling various lepidopteran pests.

Benfluralin, a pre-emergence herbicide and agrochemical, is utilized for controlling grass and various weed species in both food and non-food crop applications.

Meleagrin, a roquefortine C-derived alkaloid produced by Penicillium fungi, serves as both a class of FabI inhibitors and a lead c-Met inhibitory entity for controlling c-Met-dependent metastatic and invasive breast malignancies. It exhibits antimicrobial and anti-proliferative activities.

Dithianon is a broad-spectrum anthraquinone fungicide with excellent adhesion to the surface of leaves and fruits, effectively controlling various fungi in specific fruits and vegetables.

Perfluorohexane sulfonamide (FHxSA) serves as an inhibitor of carbonic anhydrase (CA), effectively inhibiting bovine CA and human CAII with IC50 values of 0.122 and 1.38 μM, respectively. Additionally, it acts as a delayed-action insecticide for controlling red imported fire ants (Solenopsis invicta). Furthermore, Perfluorohexane sulfonamide is considered a potential environmental pollutant.

Isazofos is a broad-spectrum organophosphate insecticide and nematicide effective in controlling a variety of lawn pests, such as nematodes (Radopholus similis). It also demonstrates efficacy in managing rice gall midge.

Profoxydim, a herbicide utilized for controlling grass weeds in rice fields, features a cyclic ketone structure. This structure comprises 3-hydroxycyclohex-2-en-1-one, which at position 2, is modified by a N-[2-(4-chlorophenoxy)propoxy]butanimidoyl group and at position 5, it is substituted by a thian-3-yl group.

The nitrofuran compound [Nifuratrone] was previously utilized for controlling Salmonella choleraesuis infections in pigs and for treating gonorrhea.

Antibacterialagent 259 (K3) is a bactericide with EC50 values of 1.5, 1.7, and 4.9 mg L against Xoo, Xoc, and Xac, respectively. It induces the production of reactive oxygen species (ROS) in pathogens, leading to their death. Antibacterialagent 259 is applicable in research for controlling bacterial diseases in plants.

Tetradifon is a broad-spectrum organochlorine acaricide insecticide and a potent inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP)，a subunit of ATP synthase. Tetradifon is utilized for controlling a variety of mite pests and inhibiting energy-related mitochondrial activities including ADP-stimulated respiration and ATPase activity with an IC50 range of 4.5-27 nmoL/mg mitochondrial protein; it exerts oligomycin-like effects by inhibiting oxidative phosphorylation, inducing significant oxidative stress, and interfering with bone metabolism, making it a compound of interest for researching mitochondrial function, bone remodeling mechanisms, and nephrotoxicity.

N-Propylbutylamine is classified as an aliphatic amine, synthesized via the reaction of butylamine with 1-propanol catalyzed by Raney nickel. Its application as a pore-directing template for controlling pore size and surface area properties of microporous mixed metal oxides has been studied.

Chlorfluazuron, a chitin synthesis inhibitor, is commonly used as an insect growth regulator for controlling the major insect pests in crops.

Enterocin (Vulgamycin) is a bacteriocin and polyketide antibiotic produced by Enterococcus spp. bacteria that is readily degraded by proteolytic hydrolysis in the gastrointestinal tract and is capable of controlling foodborne pathogens such as L. monocytogenes, Listeria, and Bacillus through human consumption. and and Bacillus.

N-hexanoyl-L-Homoserine lactone (C6-HSL), a small diffusible signaling molecule, is involved in controlling gene expression, affecting cellular metabolism, and quorum sensing.