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Prosulfuron

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Catalog No. T218813 Copy Product Info
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Prosulfuron is a fluorinated sulfonylurea herbicide with an acute oral LD50 of 546 mg/kg in female rats. It inhibits weed growth by blocking the biosynthesis of branched-chain amino acids (valine, leucine, and isoleucine) through the inhibition of acetolactate synthase (ALS). Additionally, Prosulfuron may disrupt the balance of soil microbiota in alkaline soils and has minimal chemical degradation. It is noted for its low toxicity to humans and mammals and is utilized in studies for controlling broadleaf weeds in corn and sweet corn fields.

Prosulfuron

Cas No. 94125-34-5
Pack SizePriceUSA StockGlobal StockQuantity
10 mgInquiry10-14 weeks10-14 weeks
50 mgInquiry10-14 weeks10-14 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Prosulfuron is a fluorinated sulfonylurea herbicide with an acute oral LD50 of 546 mg/kg in female rats. It inhibits weed growth by blocking the biosynthesis of branched-chain amino acids (valine, leucine, and isoleucine) through the inhibition of acetolactate synthase (ALS). Additionally, Prosulfuron may disrupt the balance of soil microbiota in alkaline soils and has minimal chemical degradation. It is noted for its low toxicity to humans and mammals and is utilized in studies for controlling broadleaf weeds in corn and sweet corn fields.
In vitro
Prosulfuron (2-10 μM) undergoes sulfonylurea bond cleavage during hydrolysis, chlorination, ozonation, and photolysis, while during UV/H2O2 treatment, it experiences arylsulfonamide hydroxylation through hydroxyl radical reactions.
Chemical Properties
Molecular Weight419.38
FormulaC15H16F3N5O4S
Cas No.94125-34-5
SmilesO=C(NC1=NC(=NC(=N1)C)OC)NS(=O)(=O)C=2C=CC=CC2CCC(F)(F)F
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 µL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Prosulfuron in vitro | Prosulfuron formula | Prosulfuron molecular weight