ck2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T23090	CK2-IN-1		Others
	CK2 inhibitor		Others
T35557	CK2 inhibitor 2		Casein Kinase
	CK2 Inhibitor 2, characterized as a potent, selective, and orally active inhibitor of CK2, demonstrates an impressive IC50 value of 0.66 nM. It exhibits high selectivity towards Clk2 with an IC50 of 32.69 nM in compariso...		Casein Kinase
T10827	CK2/ERK8-IN-1	TMCB	Apoptosis , ERK , Casein Kinase , Pim , DYRK
	CK2/ERK8-IN-1 (TMCB) is a dual inhibitor of casein kinase 2 (CK2) (Ki: 0.25 µM) and ERK8 (IC50s: 0.50 μM) with pro-apoptotic efficacy. CK2/ERK8-IN-1 also binds to PIM1, DYRK1A, and HIPK2 (Kis: 8.65 µM, 11.9 µM, and 15.25...		Apoptosis , ERK , Casein Kinase , Pim , DYRK
T40131	SGC-CK2-1	SGC-CK2-1
	SGC-CK2-1 is an ATP-competitive chemical compound that acts as a highly potent and cell-active CK2 inhibitor. It demonstrates excellent selectivity towards both isoforms of human CK2, with IC50 values of 36 nM for CK2α a...
T73375	CK2-IN-4		Casein Kinase
	CK2-IN-4 is a protein kinase (CK2) inhibitor with an IC50 value of 8.6 µM. CK2-IN-4 has potential anticancer ah and anti-inflammatory activity for the study of viral infections and glomerulonephritis diseases.		Casein Kinase
T7390	DMAT	Casein kinase II Inhibitor,CK2 Inhibitor	Casein Kinase
	DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).		Casein Kinase
T10828	CK2/PIM1-IN-1		Others
	CK2/PIM1-IN-1 is an inhibitor of CK2 and PIM1 (IC50s: 3.787 μM and 4.327 μM). It is developed for the research of proliferative disorders such as cancer, as well as other kinase-associated conditions.		Others
T61629	CK2 inhibitor 3
	CK2 inhibitor 3 is a highly potent inhibitor of protein kinase CK2, exhibiting an IC50 value of 280 nM. It effectively inhibits the intracellular activity of CK2 and displays a notable impact on the viability of tumor ce...
T78599	CK2-IN-9
	CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter activity with an IC50 of 75 nM. In rats, it demonstrates low e...
T62862	CK2-IN-3
	CK2-IN-3 is a potent and selective CK2 inhibitor (Kd: 12 nM) with IC50 values of 1.51 μM for CK2α and 7.64 μM for CK2α'. CK2-IN-3 can be used in cancer research.
T73380	CK2-IN-6
	CK2-IN-6, a powerful inhibitor of protein kinase CK2, shows promise for research in cancer, along with conditions related to kinases such as inflammation, pain, and specific immune diseases.
T63991	BRD4/CK2-IN-1
	BRD4/CK2-IN-1 is the first potent, orally active dual-target inhibitor of BRD4/CK2 (bromodomain-containing protein 4/casein kinase 2), acting on both BRD4 (IC50: 180 nM) and CK2 (IC50: 230 nM). In triple-negative breast ...
T2869	Emodin	Frangula emodin	SARS-CoV , Casein Kinase , Autophagy
	Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways.		SARS-CoV , Casein Kinase , Autophagy
T12747	ROCK2-IN-2		ROCK
	ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).		ROCK
T73269	CK2α-IN-1		Casein Kinase
	CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and can be used in cancer research.		Casein Kinase
T72695	UCK2 Inhibitor-1
	UCK2 Inhibitor-1 is a non-competitive UCK2 inhibitor with an IC 50 of 4.7 µM .
T81261	ROCK2-IN-7		ROCK
	ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis. It exhibits its efficacy in targeting ROCK2 enzymes within HaCaT cells and has demonstrated beneficial effects in a psoriasi...		ROCK
T73117	ROCK2-IN-5
	ROCK2-IN-5, a compound integrating structural elements from the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids, exhibits a favorable multitarget profile and tolerability. It shows potential ...
T79832	ROCK2-IN-6		ROCK
	ROCK2-IN-6 (Comp A) is a selective inhibitor of ROCK2, applicable in the study and treatment of ROCK-mediated, autoimmune, and inflammatory diseases [1].		ROCK
T73194	DOCK2-IN-1
	DOCK2-IN-1, an analogue of CPYPP, effectively inhibits DOCK2 (IC50 = 19.1 μM) by reversibly binding to its DHR-2 domain, thereby hindering its catalytic function. This compound obstructs the activation of Rac in lymphocy...