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IFNAR

The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human type I IFNs include many subtypes, such as interferons-α, -β, -ε, -κ, -ω, and -ζ.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T78262 Anti-Mouse IFN gamma Antibody (H22) 98%
Anti-Mouse IFN gamma Antibody (H22)
Anti-Mouse IFN Gamma Antibody is a host Armenian Hamster-derived anti-mouse IFN gamma immunoglobulin G (IgG) inhibitor.
T78263 Anti-Mouse IFNAR1 Antibody (MAR1-5A3) 98%
Anti-Mouse IFNAR1 Antibody (MAR1-5A3)
Anti-Mouse IFNAR1 Antibody (MAR1-5A3) is a neutralizing monoclonal antibody that specifically binds to IFNAR1, blocking its signaling both in vitro and in vivo. ...
T78508 Delmitide acetate 501019-16-5 98%
Delmitide acetate
Delmitide acetate (RDP58) is an orally active d-isomer decapeptide that exhibits potent anti-inflammatory properties. This compound suppresses the production of ...
T80570 Dazukibart 2639474-65-8 98%
Dazukibart
Dazukibart is a humanized IgG1κ monoclonal antibody of murine origin, specifically targeting interferon beta 1 (IFNB1) [1].
T80600 Peginterferon lambda-1a 914617-98-4 98%
Peginterferon lambda-1a
Peginterferon lambda-1a (BMS-914143) is a monoclonal antibody that targets IFNLR1 and is composed of IFNL1 conjugated to pegol [1].
TN3395 Alpinone 3-acetate 139906-49-3 98%
Alpinone 3-acetate
Alpinone 3-acetate showed anti-inflammatory effects and inhibited the inflammatory response in mouse ear edema models induced by 12-O-tetradecanophenol 13-acetat...
T76691 Monalizumab 1228763-95-8 SDS-PAGE:95% SEC-HPLC:95%
Monalizumab
Monalizumab is a novel immune checkpoint inhibitor targeting natural killer cell population 2A (NKG2A). Monalizumab is a humanized monoclonal antibody against NK...
T77432 Anifrolumab 1326232-46-5 SDS-PAGE:95% SEC-HPLC:95%
Anifrolumab
Anifrolumab(MEDI-546) is a potent type I interferon (IFN) receptor antagonist, a human monoclonal antibody that targets IFN.Anifrolumab inhibits the activity of ...
T5317 Cridanimod 38609-97-1 99.96%
Cridanimod
Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/...
T4403 AX-024 hydrochloride 1704801-24-0 99.9%
AX-024 hydrochloride
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TN...
T0244 Tilorone dihydrochloride 27591-69-1 99.84%
Tilorone dihydrochloride
Tilorone dihydrochloride is an orally active interferon inducer, and has antineoplastic and anti-inflammatory actions.
T3829 Ginsenoside F3 62025-50-7 99.84%
Ginsenoside F3
Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhan...
T13736 Interferon receptor inducer-1 2215120-36-6 99.73%
Interferon receptor inducer-1
Interferon receptor inducer-1 Used in the treatment of a disorder in which the induction of interferon is involved. is an interferon (IFN) receptor inducer.
T11630 IFN alpha-IFNAR-IN-1 hydrochloride 2070014-98-9 99.66%
IFN alpha-IFNAR-IN-1 hydrochloride
IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α resp...
T22142 RO8191 691868-88-9 98.85%
RO8191
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
T7081 CCCP 555-60-2 98.55%
CCCP
CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the ...
T14687 Deucravacitinib 1609392-27-9 98.52%
Deucravacitinib
Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for...
T6273 Vadimezan 117570-53-3 98.5%
Vadimezan
Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and in...
Anti-Mouse IFN gamma Antibody (H22)
T78262
Anti-Mouse IFN Gamma Antibody is a host Armenian Hamster-derived anti-mouse IFN gamma immunoglobulin G (IgG) inhibitor.
Anti-Mouse IFNAR1 Antibody (MAR1-5A3)
T78263
Anti-Mouse IFNAR1 Antibody (MAR1-5A3) is a neutralizing monoclonal antibody that specifically binds to IFNAR1, blocking its signaling both in vitro and in vivo. ...
Delmitide acetate
T78508
Delmitide acetate (RDP58) is an orally active d-isomer decapeptide that exhibits potent anti-inflammatory properties. This compound suppresses the production of ...
Dazukibart
T80570
Dazukibart is a humanized IgG1κ monoclonal antibody of murine origin, specifically targeting interferon beta 1 (IFNB1) [1].
Peginterferon lambda-1a
T80600
Peginterferon lambda-1a (BMS-914143) is a monoclonal antibody that targets IFNLR1 and is composed of IFNL1 conjugated to pegol [1].
Alpinone 3-acetate
TN3395
Alpinone 3-acetate showed anti-inflammatory effects and inhibited the inflammatory response in mouse ear edema models induced by 12-O-tetradecanophenol 13-acetat...
Monalizumab
T76691
Monalizumab is a novel immune checkpoint inhibitor targeting natural killer cell population 2A (NKG2A). Monalizumab is a humanized monoclonal antibody against NK...
Anifrolumab
T77432
Anifrolumab(MEDI-546) is a potent type I interferon (IFN) receptor antagonist, a human monoclonal antibody that targets IFN.Anifrolumab inhibits the activity of ...
Cridanimod
T5317
Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/...
AX-024 hydrochloride
T4403
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TN...
Tilorone dihydrochloride
T0244
Tilorone dihydrochloride is an orally active interferon inducer, and has antineoplastic and anti-inflammatory actions.
Ginsenoside F3
T3829
Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhan...
Interferon receptor inducer-1
T13736
Interferon receptor inducer-1 Used in the treatment of a disorder in which the induction of interferon is involved. is an interferon (IFN) receptor inducer.
IFN alpha-IFNAR-IN-1 hydrochloride
T11630
IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α resp...
RO8191
T22142
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
CCCP
T7081
CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the ...
Deucravacitinib
T14687
Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for...
Vadimezan
T6273
Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and in...
TargetMol