T13390 |
ZD 7155(hydrochloride)
|
146709-78-6
|
98%
|
|
ZD 7155 hydrochloride is an antagonist of angiotensin II receptor type 1 (AT1 receptor).
|
T11921 |
LY 222306
|
154446-98-7
|
98%
|
|
LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.
|
T14147 |
Pelitrexol
|
446022-33-9
|
98%
|
|
Pelitrexol (AG 2037) is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor.
|
T17257 |
WR99210
|
47326-86-3
|
98%
|
|
WR99210 is effective against the most pyrimethamine-resistant Plasmodium falciparum strains. WR99210 is an effective inhibitor of dihydrofolate reductase (IC50:<...
|
T16009 |
Managlinat dialanetil
|
280782-97-0
|
98%
|
|
Managlinat dialanetil is an orally bioavailable inhibitor of fructose 1,6-bisphosphatase (FBPase). It is used for the treatment of type 2 diabetes.
|
T19858 |
Brodimoprim
|
56518-41-3
|
98%
|
|
Brodimoprim is a structural analog of trimethoprim. Brodimoprim is also a long-acting broad-spectrum antibacterial agent characterized by a good pharmacokinetic ...
|
T36692 |
Fanotaprim
|
2120282-75-7
|
98%
|
|
Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor with IC50s of 1.57 and 308 nM for tgDHFR (Toxoplasma gondii DHFR) and hDHFR (human DHFR), respectively. ...
|
T15826 |
Lometrexol
|
106400-81-1
|
98%
|
|
Lometrexol, an antipurine Antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA...
|
T4558 |
Trioxsalen
|
3902-71-4
|
100%
|
|
Trioxsalen is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation ...
|
T1326 |
Gentamicin sulfate
|
1405-41-0
|
651u/mg
|
|
Gentamycin Sulfate is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms.
|
T0738 |
Urea
|
57-13-6
|
98%
|
|
Urea is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for ab...
|
T6120 |
Pralatrexate
|
146464-95-1
|
98.12%
|
|
Pralatrexate is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic a...
|
T0836 |
Sulfadoxine
|
2447-57-6
|
98.36%
|
|
Sulfadoxine is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial properties.
|
T6226 |
Pemetrexed disodium hemipenta hydrate
|
357166-30-4
|
99.16%
|
|
Pemetrexed Disodium Hydrate is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is ...
|
T2204 |
Diaveridine
|
5355-16-8
|
99.19%
|
|
Diaveridine (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide. It has been reported to be genotoxic to mammalian cel...
|
T15827 |
LY 345899
|
10538-99-5
|
99.69%
|
|
LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHF...
|
T0849 |
Pyrimethamine
|
58-14-0
|
99.74%
|
|
Pyrimethamine is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.
|
T0748 |
Sulfameter
|
651-06-9
|
99.85%
|
|
Sulfameter is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and leprosy.
|
T1153 |
Trimethoprim
|
738-70-5
|
99.88%
|
|
Trimethoprim is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochr...
|
T0189L |
Pemetrexed disodium
|
150399-23-8
|
99.92%
|
|
Pemetrexed is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesotheli...
|