pro 2

[D-Pro2,D-Trp7,9] Substance P, an analogue of Substance P, acts as both a weak agonist and a potent, specific, competitive antagonist to Substance P [1] [2].

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B functions as a competitive antagonist to the Neurokinin B receptor with a pA2 value of 5.5, and does not affect Substance P or Neurokinin A [1].

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P is a neuropeptide Substance P antagonist [1].

(D-Arg1, D-Pro2, D-Phe7, D-His9)-Substance P is a selective NK1 receptor antagonist [1].

[D-Pro2] Spantide I TFA is an analog of Spantide I, serving as a selective antagonist of the NK1 receptor [1].

[D-Pro2,D-Phe7,D-Trp9] Substance P, an analogue of Substance P, serves as an inhibitor to its parent compound and indirectly contracts the guinea-pig ileum (GPI) [1] [2].

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate), an antagonist of Substance P and Bombesin, modulates ocular inflammatory responses triggered by antidromic trigeminal nerve stimulation [1].

H-Pro-2-ClTrt resin is an acid-labile resin utilized in solid-phase peptide synthesis. It covalently bonds amino acids through an acid-sensitive 2-chlorotrityl (ClTrt) linker. H-Pro-2-ClTrt resin holds potential for research in peptide drug development.

[Des-Pro2]-Bradykinin acts as a protease inhibitor that prevents the degradation of methionine enkephalin [1].

PGlu-3-methyl-His-Pro-NH2 TFA enhances binding to pituitary TRH receptors, thereby increasing the stimulation of thyroid-stimulating hormone (TSH) release from the pituitary.

Mca-Pro-Leu-NH2 is a peptide compound and a substrate for matrix protease assays.

pFR-pNA, chromogenic substrate for the determination of plasma kallikrein-like activity. CAS Number (net): 64816-19-9.

Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 is a peptide substrate specific to HIV-1 protease, used as the variable component in peptidolytic assays designed to measure the enzyme's inhibition [1][2].

H-Gly-Pro-Gly-NH2, a tripeptide, effectively inhibits HIV-1 replication by interfering with capsid formation, demonstrating antiviral activity particularly against HIV-1 III B and HIV-2 ROD with EC 50 values of 35 µM and 30 µM, respectively. This compound's ability to disrupt the viral replication process positions it as a valuable asset for virus research [1] [2] [3].

Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biologically active peptide. Structure-activity studies of the thrombin receptor-tethered ligand SFLLRNP highlighted the pivotal role of the Phe-2-phenyl group in receptor recognition, while substitution with para-fluorophenylalanine [(p-F)Phe] increased its activity.

pGlu-His-Pro-Gly-NH2, also known as Glp-His-Pro-Gly-NH2, is a tetrapeptide that promotes the release of gonadotropin, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) [1] [2].

H-Pro-NH2 is an amino acid derivative and has a wide range of applications in life science related research.

(D-Met2,Pro5)-Enkephalinamide, a highly potent opiate agonist, exhibits significant antinociceptive activity.

PRO-HD2 is a selective, PROTAC-based degrader of HDAC6 [1].

Compound 11, also known as NS2B-NS3pro-IN-2, functions as an inhibitor of the Zika Virus NS2B-NS3 protease and exhibits antiviral properties at a concentration of 50 μM [1].

NS2B-NS3pro-IN-1, a potent Zika Virus NS2B-NS3 protease inhibitor, exhibits an EC50 of 50 μM and is significant in the ZIKV replication cycle [1].

H-Gly-Pro-Arg-Pro-NH2 is a tetrapeptide that mimics the N-terminal Gly-Pro-Arg sequence in the alpha (α) chain of fibrin, inhibiting its polymerization [1].

Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2 is a linear peptide derived from the laminin B1 chain, disrupting tumor cell adherence and invasion into the basement membrane and exhibiting anti-angiogenic properties [1].

(2R,4S)-Boc-D-Pro(4-N3)-OH is a click chemistry reagent possessing an azide group. This compound is capable of undergoing copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing alkyne groups. Additionally, it can participate in strain-promoted azide-alkyne cycloaddition reactions (SPAAC) with compounds that have DBCO or BCN groups.