eye

Influenza A H5N1 (A Japanese white-eye Hong Kong 1038 2006) Hemagglutinin HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is A0FFY3.

Influenza A H5N1 (A Japanese white-eye Hong Kong 1038 2006) Hemagglutinin HA1 Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is A0FFY3.

Influenza A H5N1 (A Japanese white-eye Hong Kong 1038 2006) Hemagglutinin HA Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is A0FFY3.

Influenza A H5N1 (A Japanese white-eye Hong Kong 1038 2006) Hemagglutinin HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is A0FFY3.

Expression system: E. coli
Length: 38-208, Full Length of Mature Protein
Activity: Organoid Coculture、Cells

Expression system: HEK293 Cells
Length: 31-229, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 59-660, Lumenal Domain
Activity: Not Tested

Expression system: HEK293 Cells
Length: 23-350, Partial
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 23-447, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1-359, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 32-266, Full Length of Mature Protein
Activity: ELISA

The Secreted frizzled-related protein (SFRP) family consists of five secreted glycoproteins in humans (SFRP1~5) that act as extracellular signaling ligands. Each SFRP is approximately 3 amino acids in length and contains a cysteine-rich domain (CRD) that shares 3-5% sequence homology with the CRD of Frizzled (Fz) receptors, a putative signal sequence, and a conserved hydrophilic carboxy-terminal domain. SFRPs are able to bind Wnt proteins and Fz receptors in the extracellular compartment. The interaction between SFRPs and Wnt proteins prevents the latter from binding the Fz receptors. The Wnt pathway plays a key role in embryonic development, cell differentiation and cell proliferation. sFRP2 is a member of the SFRP family acting as soluble modulators of Wnt signaling and contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins called FZ domain and a NTR domain.sFRP2 inhibites hypoxia induced endothelial cell apoptosis and increases endothelial cell migration. It prevents mesoderm specification and maintains the cells in the undifferentiated state. SFRP2 is also a novel stimulator of angiogenesis that stimulates angiogenesis via a calcineurin NFAT pathway, thus is regarded as a favorable target for the inhibition of angiogenesis in solid tumors. Mouse sFRP2 is highly expressed in the eye and is also detected in heart and lung at low level.

COL2A1 is the alpha-1 chain of type II collagen which is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this protein are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. Type II collagen is specific for cartilaginous tissues. Thus COL2A1 is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. The regulation of COL2A1, likely results from a balance of both positive and negative proteins. The inhibition of COL2A1 transcription following treatment of chick sternal chondrocytes with growth factors was accompanied by increased EF1 expression. Overexpression of EF1 in differentiated chondrocytes resulted in decreased expression of a reporter construct containing a collagen II promoter enhancer insert.

Expression system: HEK293 Cells
Length: 31-454, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 23-350, Partial
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 1321-1569, Partial
Activity: Not Tested

Expression system: E. coli
Length: 128-223, Partial
Activity: Not Tested

FGF-1 Protein, Bovine, Recombinant (His) is expressed in Yeast. The accession number is P03968.

Expression system: HEK293 Cells
Length: 279-390, Partial
Activity: Cell Activity

Expression system: E. coli
Length: 1-552, Full Length
Activity: Not Tested

Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

Expression system: HEK293 Cells
Length: 12660-12923 (mutation), Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 31-455, Extracellular Domain
Activity: Not Tested

Expression system: E. coli
Length: 23-541, Partial
Activity: Not Tested