PARP

Poly (ADP-ribose) polymerase (PARP) is a family of proteins involved in a number of cellular processes such as DNA repair, genomic stability, and programmed cell death.

Cat. No.	Product name	CAS No.	Purity
TN1663	Ganoderic acid DM	173075-45-1	98%
TN1663	Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 ...
TN4932	Sageone	142546-15-4	98%
TN4932	Sageone represents a promising anticancer agent against gastric cancer that warrants further study, it synergizes with cisplatin cytotoxicity in SNU-1 human gast...
T11992	Mefuparib hydrochloride	1449746-00-2	98%
T11992	Mefuparib hydrochloride induces apoptosis and possesses prominent anticancer activity in vitro and in vivo. Mefuparib hydrochloride (MPH) is an orally active, su...
TN1642	Ferruginol	514-62-5	98%
TN1642	Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce ap...
TN3525	Boehmenan	57296-22-7	98%
TN3525	(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in ...
TN2511	Britannilactone diacetate	1286694-67-4	98%
TN2511	1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airwa...
TN1458	Buddlejasaponin IV	139523-30-1	98%
TN1458	Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-ka...
T16979	Talazoparib tosylate	1373431-65-2	98%
T16979	Talazoparib tosylate is a novel and potent PARP1/2 (n IC50: 0.57 nM for PARP1).
TN4999	Serratenediol	2239-24-9	98%
TN4999	Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects be...
TN3619	Cedrusin	75775-36-9	98%
TN3619	Cedrusin shows a cytotoxic effect on A375 and HeLa cells.
TN4340	Ivangustin	14164-59-1	98%
TN4340	Ivangustin exhibits remarkable cytotoxicity against HEp2, SGC-7901 and HCT116 human cancer cell lines.
TN4637	Neogrifolin	23665-96-5	98%
TN4637	Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS ...
T12366	PARP14 inhibitor H10	2084811-68-5	98%
T12366	PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM
TN2106	Protodeltonin	94992-08-2	98%
TN2106	Protodeltonin may have anti-thrombotic activity by both improving the anticoagulation activity and inhibiting platelet aggregation action. Protodeltonin can inhi...
TN4341	IVHD-valtrate	28325-56-6	98%
TN4341	VHD-valtrate has anticancer effects against human ovarian cancer cells in vitro and in vivo, it is a potential therapeutic agent for ovarian cancer, providing a ...
TN3922	Effusanin E	76470-15-0	98%
TN3922	Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p6...
TN1139	Dehydrocavidine	83218-34-2	98%
TN1139	Dehydrocavidine has antitumor activity, it inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well ...
TN3070	4beta-Hydroxywithanolide E	54334-04-2	98%
TN3070	4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progr...
TN1837	Kuguaglycoside C	1041631-93-9	98%
TN1837	Kuguaglycoside C induces caspase-independent cell death, and is involved, at least in part, in the mechanism underlying cell necroptosis.
TN4028	Euchrestaflavanone B	87402-91-3	98%
TN4028	Euchrestaflavanone B shows antibacterial activity against Gram positive bacteria, Staphylococcus aureus, Bacillus subtilis and Bacillus cereus. Euchrestaflavanon...