td-1

Transdermal Peptide (TD 1 peptide) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide can enhance the transdermal delivery of many macromolecules.Transdermal Pep

Transdermal Peptide TD-1 HCl is a novel peptide for enhanced transdermal drug delivery that facilitates the penetration of the skin barrier by several drugs and large hydrophilic proteins, such as insulin and human growth hormoneb.

TD-165, a PROTAC-based cereblon (CRBN) degrader, consists of a cereblon (CRBN) ligand-binding group, a linker, and a von Hippel-Landau (VHL) binding group[1].

TD-106 is a modulator of cereblon (CRBN), and can be used for targeted protein degradation. BRD4 PROTACs with TD-106 induce BRD4 degradation.

(+)-ITD-1 is an inhibitor of TGF-β, effectively inhibiting TGF-β2 with an IC50 of 0.46 μM. It promotes the degradation of the TGF-β type II receptor (TGFBR2) and the differentiation of cardiomyocytes. Additionally, it suppresses the formation of the mesoderm during the early differentiation of mouse embryonic stem cells (mESCs).

ITD-1 is a potent and highly selective TGFβ pathway inhibitor.

NMK-TD-100 is a microtubule modulating agent with anti-proliferative activity by disrupting microtubule functions through tubulin binding. NMK-TD-100 blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin. Polymerization of tissue purifi

TD-198946, a potent chondrogenic agent, is a thienoindazole derivative.

EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM.

Izencitinib (JNJ-8398) is an orally active and gut-selective JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.

TD139 is a small molecule inhibitor of inhaled galectin-3 (Gal-3) with potential anti-fibrotic activity, commonly used in the study of idiopathic pulmonary fibrosis.

Berberine ursodeoxycholate (HTD1801) is an orally effective hypolipidemic agent, an ionic salt of Berberine and Ursodeoxycholic acid.Berberine ursodeoxycholate has a wide range of metabolic activity and significantly reduces liver fat content. Berberine ursodeoxycholate has been used in studies of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes.

OR015002 shows toxicity to T. pyriformis with log(IGC50^-1) of 0.75.

4-Hydroxyindole is an aromatic heterocyclic compound that is widely studied in both scientific research and laboratory experiments. 4-Hydroxyindole is known for its antioxidant properties and has been used in a variety of applications, from cancer treatments to the prevention of neurodegenerative diseases.

1,3-Cyclohexadiene is used in the synthesis of many biologically active compounds and polymers.

MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.

1-(3-METHYLBENZYL)PIPERAZINE, with CAS No. 5321-48-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-(3-METHYLBENZYL)PIPERAZINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

PTH-GLYCINE, with CAS No. 2010-15-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. PTH-GLYCINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-phenylpyrazolidine-3,5-dione, with CAS No. 19933-22-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-phenylpyrazolidine-3,5-dione provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

N-(3-aminobenzyl)-N,N-diethylamine, with CAS No. 27958-97-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. N-(3-aminobenzyl)-N,N-diethylamine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

THIOPHENE-2-ACETAMIDE, with CAS No. 4461-29-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. THIOPHENE-2-ACETAMIDE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-BENZYLINDOLE, with CAS No. 3377-71-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-BENZYLINDOLE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-BENZYL-1(2H)-PHTHALAZINONE, with CAS No. 32003-14-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-BENZYL-1(2H)-PHTHALAZINONE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(4-CHLOROPHENYL)PHENYLMETHYLAMINE HYDROCHLORIDE, with CAS No. 28022-43-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (4-CHLOROPHENYL)PHENYLMETHYLAMINE HYDROCHLORIDE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.