td 1

Transdermal Peptide (TD 1 peptide) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide can enhance the transdermal delivery of many macromolecules.Transdermal Pep

Transdermal Peptide TD-1 HCl is a novel peptide for enhanced transdermal drug delivery that facilitates the penetration of the skin barrier by several drugs and large hydrophilic proteins, such as insulin and human growth hormoneb.

Transdermal Peptide is a 11-amino acid peptide, binds to Na+/K+-ATPase beta-subunit (ATP1B1), and enhances the transdermal delivery of many macromolecules. Transdermal Peptide (TD1) binds to ATP1B1, and mainly interacts with the C-terminus of ATP1B1 in yeast and mammalian cells. The interaction affects the expression and localization of ATP1B1 and epidermal structure, but can be antagonized by the exogenous competitor ATP1B1 or be inhibited by ouabain. Inhibition of Transdermal Peptide binding to ATP1B1 causes decreased delivery of macromolecular drugs across the skin[1]. [1]. Wang C, et al. Role of the Na(+)/K(+)-ATPase beta-subunit in peptide-mediated transdermal drug delivery. Mol Pharm. 2015 Apr 6;12(4):1259-67.

AAL Toxin TD1 is a useful organic compound for research related to life sciences and the catalog number is T125565.

EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM.

Izencitinib (JNJ-8398) is an orally active and gut-selective JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.

TD139 is a small molecule inhibitor of inhaled galectin-3 (Gal-3) with potential anti-fibrotic activity, commonly used in the study of idiopathic pulmonary fibrosis.

Berberine ursodeoxycholate (HTD1801) is an orally effective hypolipidemic agent, an ionic salt of Berberine and Ursodeoxycholic acid.Berberine ursodeoxycholate has a wide range of metabolic activity and significantly reduces liver fat content. Berberine ursodeoxycholate has been used in studies of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes.

OR015002 shows toxicity to T. pyriformis with log(IGC50^-1) of 0.75.

4-Hydroxyindole is an aromatic heterocyclic compound that is widely studied in both scientific research and laboratory experiments. 4-Hydroxyindole is known for its antioxidant properties and has been used in a variety of applications, from cancer treatments to the prevention of neurodegenerative diseases.

1,3-Cyclohexadiene is used in the synthesis of many biologically active compounds and polymers.

MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.

1-(3-METHYLBENZYL)PIPERAZINE, with CAS No. 5321-48-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-(3-METHYLBENZYL)PIPERAZINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

PTH-GLYCINE, with CAS No. 2010-15-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. PTH-GLYCINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-phenylpyrazolidine-3,5-dione, with CAS No. 19933-22-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-phenylpyrazolidine-3,5-dione provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

N-(3-aminobenzyl)-N,N-diethylamine, with CAS No. 27958-97-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. N-(3-aminobenzyl)-N,N-diethylamine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

THIOPHENE-2-ACETAMIDE, with CAS No. 4461-29-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. THIOPHENE-2-ACETAMIDE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-BENZYLINDOLE, with CAS No. 3377-71-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-BENZYLINDOLE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-BENZYL-1(2H)-PHTHALAZINONE, with CAS No. 32003-14-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-BENZYL-1(2H)-PHTHALAZINONE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(4-CHLOROPHENYL)PHENYLMETHYLAMINE HYDROCHLORIDE, with CAS No. 28022-43-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (4-CHLOROPHENYL)PHENYLMETHYLAMINE HYDROCHLORIDE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2,6-DICHLOROPHENYLACETAMIDE, with CAS No. 78433-88-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2,6-DICHLOROPHENYLACETAMIDE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7H-Pyrrolo[2,3-c]pyridin-7-one,1,6-dihydro-, with CAS No. 259684-36-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7H-Pyrrolo[2,3-c]pyridin-7-one,1,6-dihydro- provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

EN300-1272604, with CAS No. 166904-37-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. EN300-1272604 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Pyrrolidin-2-yl-thiazole dihydrochloride, with CAS No. 1965309-49-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Pyrrolidin-2-yl-thiazole dihydrochloride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.