ptk

Ginsenoside Ra1, a component from ginseng, exhibits significant inhibitory effects on protein tyrosine kinase (PTK) activation induced by hypoxia reoxygenation (H R).

1. 3''-Galloylquercitrin possesses the activity for PTK inhibition.

Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly decreased viability of HCT116 cells (IC50 values = 30.9 μg mL).