nnos

Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GABA analog with neuroprotective, anticonvulsant, and antihypertensive activity.

3-Bromo-7-nitroindazole is a specific neuronal nitric oxide synthase (nNOS) inhibitor that affects the synthesis of the intercellular messenger NO throughout the brain and body.

L-NAME hydrochloride (L-NAME HCl), a cell-permeable NO synthase inhibitor, displays Ki values of 4.4 μM, 15 nM, and 39 nM, for iNOS (mouse) , nNOS (bovine) , and eNOS (human), respectively.

nNOS-IN-25 is an effective, selective, and cell-permeable inhibitor of neuronal nitric oxide synthase.

Cyclic N-Acetyl-D-mannosamine is a monosaccharide used as a precursor in the chemical or enzymatic synthesis of neuraminic acid found in glycolipids and glycoproteins.N-Acetyl-D-mannosamine is a specific substrate for the synthesis of n -acetylneuraminic acid, an essential precursor for bacterial podoplanar polysialic acid (PA).N-Acetyl-D-mannosamine is used in the synthesis of sialic acid. mannosamine is used in the synthesis of sialic acid. It is also an intermediate in the synthesis of many carbohydrate-derived bioactive compound families and drug candidates.N-Acetyl-D-mannosamine is used in the study of cognitive disorders and aging.

D-Mannose (D-(+)-Mannose) is a carbohydrate. D-Mannose plays an important role in human metabolism, especially in the glycosylation of specific proteins.

Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.

Sennoside C is an anthraquinone glycoside extracted from leaves and pods of Senna and has an auxiliary effect on the laxative effect of mice.

GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM).GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of

Sennoside A1 is a useful organic compound for research related to life sciences and the catalog number is T124434.

Azido-PEG4-alpha-D-mannose is a PEG-based PROTAC linker used in the synthesis of PROTACs [1].

N-Acetyl-D-mannosamine (ManNAc) is a potential drug for treating hereditary inclusion body myopathy.

DSPE-PEG(2000)-mannose, a pegylated and mannosylated derivative of 1,2-DSPE, has been employed in both in vitro and in vivo studies for delivering peptides, oligodeoxynucleotides, and siRNA via liposomes and lipid nanoparticles (LNPs). Fluorescently labeled LNPs containing DSPE-PEG(2000)-mannose predominantly accumulate in the liver and spleen of mice, significantly more so than in the brain, lungs, heart, kidneys, and pancreas. In immunization studies, liposomes encapsulating Human Papillomavirus type 16 (HPV16) E7 peptides with CpG oligodeoxynucleotides as an adjuvant led to reduced tumor volume and decreased numbers of CD4+ or CD8+ T cells and angiogenesis within tumors in a mouse lung cancer model using TC-1 cells.

Mannose 6-phosphate (M6P) features a type I integral membrane receptor.

Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.

Sennoside D is an anthraquinone glycoside extracted from leaves and pods of Cassia angustifolia.

Trimannosyldilysine is a bioactive chemical.

D-Mannose-6-Phosphate sodium salt hydrate is a multifunctional monosaccharide used in the study of metabolism, lysosomal delivery and cancer.

GDP-D-mannose disodium is a natural product for research related to life sciences and the catalog number is T65209.

Mannose 1-phosphate, an endogenous metabolite, serves as a substrate for the enzyme GDP-mannose pyrophosphorylase to synthesize GDP-Man [1].

Compound 17, also known as hnNOS-IN-2, is an inhibitor of human neuronal nitric oxide synthase (hnNOS) that exhibits good metabolic stability. It is potentially useful for research into neurodegenerative diseases [1].

Phosphomannose isomerase, the initial enzyme in GDP-Man biosynthesis, catalytically facilitates the interconversion of fructose-6-phosphate (Fru6P) and mannose-6-phosphate (Man6P), playing a crucial role in cell wall synthesis and protein glycosylation. It is also recognized as a significant antifungal target against threats from A. flavus [1].

Paucimannose, a prevalent mannosidic N-glycoepitope found in invertebrates and plants, is also expressed in cancers [1].

L-(-)-Mannose ((2R,3R,4S,5S)-2,3,4,5,6-pentahydroxyhexanal) is a naturally occurring non-reducing sugar commonly used as a food additive.