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  • Melanocortin Receptor
    (40)
  • Melanin-concentrating Hormone Receptor (MCHR)
    (2)
  • Adenylyl Cyclase
    (1)
  • Potassium Channel
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  • Others
    (23)
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Results for "

melanocortin

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    97
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    61
    TargetMol | Peptide_Products
  • Natural Products
    1
    TargetMol | Natural_Products
  • Recombinant Protein
    2
    TargetMol | Recombinant_Protein
PF-07258669
T695262755890-53-8In house
PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.
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10-14 weeks
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TargetMol | Inhibitor Hot
Undecylenoyl phenylalanine
Undecylenoylphenylalanine, Sepiwhite msh QD
T20501175357-18-3
Undecylenoyl phenylalanine (Sepiwhite msh QD) is a novel depigmenting agent, which possibly acts as an alpha-melanocyte-stimulating hormone antagonist, thus inhibiting melaninogenesis.
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4-6 weeks
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Dersimelagon
MT-7117
T253101835256-48-8
Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values ​​of 8.16, 3.91, 1.14, and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m), and rat (r) MC1R, respectively. Dersimelagon exhibits good affinity for hMC1R and hMC4R, with Ki values ​​of 2.26 and 32.9 nM, respectively. Dersimelagon can be used in the study of skin pigmentation[1].
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10-14 weeks
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ACTH (1-17) acetate
TP1011L
ACTH (1-17) acetate is a potent agonist at the human melanocortin 1 (MC1) receptor with high affinity(Ki = 0.21 nM).
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α-MSH
MSH, amide, CZEN-002, α-Melanocyte-Stimulating Hormone (MSH), amide
T7813581-05-5
α-MSH (MSH, amide) is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
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THIQ
T8485312637-48-2
THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).
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AP1189 acetate
T9596959850-74-9
AP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors.
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ACTH 11-24 acetate(4237-93-8 free base)
Adrenocorticotropic Hormone (11-24) acetate
TP1248L79190-56-0
ACTH 11-24 acetate(4237-93-8 free base) (Adrenocorticotropic Hormone (11-24) acetate) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells.
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MCL0020
MCL 0020
TP1889475498-26-1
MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115, and >10,000 nM at MC4, MC3, and MC1 receptors, respectively). It significantly reverses stress-induced anorexia without affecting food intake in free-feeding rats and exhibits anxiolytic-like activity in vivo.
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[D-Trp8]-γ-MSH acetate(321351-81-9 free base)
TP1893L1
[D-Trp8]-γ-MSH acetate(321351-81-9 free base) is a selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively) and displays anti-inflammatory efficacy.
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PG 106 acetate
PG 106 acetate(944111-22-2 Free base)
TP1952L
PG 106 acetate is an effective and selective antagonist of the human melanocortin 3 (hMC3) receptor with an IC50 of 210 nM. PG 106 acetate has no activity with the hMC5 receptor and hMC4 receptors with an EC50 of 9900 nM.
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HS 014 acetate(207678-81-7 free base)
TP2015L
HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and nociception in mice following central
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Fenoprofen
Nalgesic, Nalfon
T0184L29679-58-1
Fenoprofen (LILLY-5385) is a non-steroidal anti-inflammatory compound and a modifier enhancer of the melanocortin receptor, which increases ERK1 2 activation, inhibits biofilm formation, and alters biofilm structure, and is used in the treatment of acute pain and chronic arthritis.
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7-10 days
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MC-4R Agonist 1
T10230455957-28-5
MC-4R Agonist 1 is an agonist of the human melanocortin-4 receptor (MC-4R) and is useful in researching sexual dysfunction, obesity, and diabetes.
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6-8 weeks
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Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA
ACTH (1-39) (mouse, rat) TFA
T10251
Adrenocorticotropic Hormone (ACTH) (1-39), rat (TFA), is a potent agonist of the melanocortin 2 receptor (MC2).
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BMS-470539 dihydrochloride
BMS470539 dihydrochloride, BMS 470539 dihydrochloride
T105682341796-82-3
BMS-470539 dihydrochloride is a selective and highly potent melanocortin 1 receptor (MC-1 R) agonist with anti-inflammatory activity. BMS-470539 attenuates oxidative stress and neuronal apoptosis via the MC1R cAMP PKA Nurr1 signaling pathway in a neonatal hypoxia-ischemia rat model.
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6-8 weeks
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ML-00253764 hydrochloride
T120721706524-94-8
ML-00253764 hydrochloride is an antagonist of nonpeptidic melanocortin receptor 4 (MC4R) (Ki and IC50 of 0.16 µM and 0.103 µM, respectively).
    7-10 days
    Inquiry
    PF-00446687
    T12415862281-92-3
    PF-00446687 is a selective agonist of melanocortin-4 receptor (MC4R) (EC50 of 12 ± 1 nM).
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    10-14 weeks
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    Setmelanotide
    RM-493, IRC-022493, BIM-22493
    T12882920014-72-8
    Setmelanotide (BIM-22493) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
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    Setmelanotide Acetate(920014-72-8 free base)
    RM-493 Acetate, IRC-022493 Acetate, BIM-22493 Acetate
    T12882L2759937-80-7
    Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
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    SNT-207707
    T129441064662-40-3
    SNT-207707 is a potent, selective and orally active antagonist of melanocortin MC-4 receptor(IC50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor).
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    6-8 weeks
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    SNT-207858 free base
    T129451104662-66-9
    SNT-207858 free base is a selective, blood brain barrier penetrating, potent and orally active antagonist of melanocortin-4 (MC-4) receptor(IC50 of 22 nM (binding) and 11 nM (function), on the MC-4 receptor).
    • Inquiry Price
    6-8 weeks
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    SNT-207858
    T129461104080-42-3
    SNT-207858 is a selective, blood brain barrier penetrating, potent and orally active antagonist of melanocortin-4 (MC-4) receptor. SNT207858 has an IC50 of 22 nM (binding) and 11 nM (function) on the MC-4 receptor.
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    6-8 weeks
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    MK-0493
    T16086455956-93-1
    MK-0493 is an effective and selective agonist of the melanocortin receptor 4 (MC4R). It also demonstrated significant reductions in energy intake.
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    8-10 weeks
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