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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
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Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
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Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
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Search Result

Search Results for " alk "

Targets

ALK DNA Alkylation DNA Alkylator/Crosslinker ALK

213

Compounds

6

Natural Products

91

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T11184 EML4-ALK kinase inhibitor 1 EML4 ALK kinase inhibitor 1,EML4-​ALK kinase inhibitor 1 ALK
EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.
T10285 ALK inhibitor 1 FAK , IGF-1R , ALK
ALK inhibitor 1 is a selective ALK kinase inhibitor.
T3041 ALK inhibitor 2 FAK , ALK
ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.
T3059 ALK-IN-1 AP26113,Brigatinib,AP26113-analog EGFR , IGF-1R , ALK
ALK-IN-1 (AP26113) is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, demonstrated ability overcome Crizotinib resistance mediated by a L1196M mutation. Phase 2.
T6409 ALK kinase inhibitor-1 SAR348830 Others
SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase.
T67699L ALK/ROS1 inhibitor 2e HCL (R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride(2365497-12-5 Free base) Apoptosis
ALK/ROS1 inhibitor 2e HCL possesses anti-apoptotic, anti-proliferative and anti-tumour activities.
T1967 AZD-3463 ALK/IGF1R inhibitor Apoptosis , IGF-1R , ALK , Autophagy
AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.
T29867 ALK-001 C-20D3vitamin A,C-20-D3-Retinyl Acetate,ALK 001,ALK001,C-20-D3-vitamin A
ALK-001 is a vitamin A analog, which may be used to treat Stargardt disease.
T39896 ALK-IN-9
ALK-IN-9 (compound 40) is a highly effective ALK inhibitor. It demonstrates remarkable inhibitory activity against cell proliferation, with IC50 values of <0.2 nM for Ba/F3-EML4-ALK, KM 12 (TPM3-TRKA), and KG-l cell (OP2...
T38583 ALK-IN-13
ALK-IN-13 is an ALK inhibitor.
T38584 ALK-IN-12
ALK-IN-12 is a highly potent and orally active inhibitor of anaplastic lymphoma kinase (ALK), demonstrating an exceptional IC50 value of 0.18 nM. Additionally, ALK-IN-12 displays inhibitory activity against insulin-like ...
T10283 ALK-IN-5 ALK
ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK, IC50: 2.9 nM).
T10284 ALK-IN-6 Others
ALK-IN-6 is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK, IC50s: 71 nM, 18.72 nM, and 36.81 nM for ALK wild, ALK F1196M and ALK F1174L).
T10286 ALK/ROS1-IN-1 Others
ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor (IC50s: 0.530 μM and 0.174 μM for ROS1 and ALK enzyme).
T63130 ALK-IN-22
ALK-IN-22 (compound I-24) is a potent inhibitor of ALK, acting on ALK (IC50: 2.3 nM), ALKL1196M (IC50: 3.7 nM), ALKG1202R (IC50: 2.9 nM). ALK-IN-22 down-regulates phosphorylation of ALK and its downstream proteins and in...
T74522 ALK-IN-21
ALK-IN-21 (Compound B10), a proficient ALK inhibitor targeting the ALKG1202R mutation, demonstrates significant inhibitory activity, with IC50 values of 4.59 nM against ALK WT, 2.07 nM against ALK L1196M, and 5.95 nM aga...
T83146 ALK-IN-27
ALK-IN-27 (compound 1) is a potent ALK inhibitor exhibiting antitumor activity, with an IC50 of 2.7 nM in Ba/F3 CLIP1-LTK cells [1].
T64027 ALK-IN-23
ALK-IN-23 is a potent inhibitor of ALK, acting on ALKWT (IC50: 1.6 nM), ALKL1196M (IC50: 0.71 nM) and ALKG1202R (IC50: 1.3 nM). -IN-23 has inhibitory effects on cancer cell migration and colony formation in vitro. In the...
T79394 ALK/EGFR-IN-3
ALK/EGFR-IN-3 is a dual ALK and EGFR inhibitor that demonstrates potent anti-proliferative effects on various cancer cell lines, including H1975, PC9, and Baf3-EML4-ALK, with respective IC50 values of 0.1360, 0.0332, and...
T79392 ALK/EGFR-IN-1 EGFR
ALK/EGFR-IN-1 (Compound 8l) is a dual inhibitor targeting both ALK and EGFR, effectively blocking their phosphorylation. It demonstrates potent inhibition of ALK/EGFR mutants with IC50 values of 4.3 nM for EGFR L858R T79...
T72931 TRK/ALK-IN-1
TRK/ALK-IN-1 is a potent dual inhibitor of TRK and ALK, exhibiting good correlation between its enzymatic inhibition and anti-proliferative activities, with IC50 values of 2.2 nM for TRKA, 9.3 nM for ALK WT, and 38 nM fo...
T79393 ALK/EGFR-IN-2
ALK/EGFR-IN-2 is a potent dual inhibitor targeting ALK and EGFR, promoting apoptosis and G0/G1 cell cycle arrest in cancer cells. It effectively suppresses proliferation in H1975, PC9, and Baf3-EML4-ALK cancer cell lines...
T26394 6-Alkynyl-fucose 6-Alk-Fuc
6-Alkynyl-fucose, a widely used fucosylation probe, acts by strongly inhibiting fucosylation and GDP-fucose synthetase FX and halting hepatoma invasion.
T82873 Biotin-PEG-Alk (MW 10000)
Biotin-PEG-Alk (MW 10000) is a biotinylated polyethylene glycol (PEG) derivative featuring an alkyne group for click chemistry applications. This compound combines biotin, an enzyme co-factor used in protein labeling, wi...
T82869 Biotin-PEG-Alk (MW 600)
Biotin-PEG-Alk (MW 600) is a biotin-labeled, alkyne-functionalized polyethylene glycol utilized as a click chemistry reagent for protein, peptide, and oligonucleotide modification [1]. Containing an alkyne group, it is d...
T82871 Biotin-PEG-Alk (MW 20000)
Biotin-PEG-Alk (MW 20000) is a biotin-labeled polyethylene glycol (PEG) derivative featuring a terminal alkyne group for efficient click chemistry applications. Serving as an enzymatic cofactor, biotin provides specific ...
T82874 Biotin-PEG-Alk (MW 1000)
Biotin-PEG-Alk (MW 1000) is a biotinylated polyethylene glycol (PEG) derivative with alkyne functionality for click chemistry applications. Biotin serves as an enzyme co-factor suitable for protein labeling, while PEG pr...
T82872 Biotin-PEG-Alk (MW 2000)
Biotin-PEG-Alk (MW 2000) is a biotin-labeled polyethylene glycol (PEG) derivative featuring an alkyne group for click chemistry applications. This compound, efficiently binding to biotin targets due to the alkyne moiety ...
T82870 Biotin-PEG-Alk (MW 3400)
Biotin-PEG-Alk (MW 3400), a biotinylated polyethylene glycol (PEG) compound with an alkyne group, serves as a versatile click chemistry reagent. The biotin moiety acts as an enzyme cofactor desirable for protein labeling...
T10287 ALK2-IN-2 ALK , TGF-beta/Smad
ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) (IC50: 9 nM), inhibiting ALK2 700-fold more than ALK3.
T14185 Alkynyl Palmitic Acid Others , PROTAC Linker
Alkynyl Palmitic Acid is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
T15612 JH-VIII-157-02 Microtubule Associated , ALK
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L...
T2612 CEP-28122 ALK
CEP-28122 is a highly potent and selective orally active ALK inhibitor.
T3079 GSK1838705A IGF-1R , JNK , S6 Kinase , ALK
GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 nM) and ALK (IC50: 0.5 nM), respectively, and little inhibition to other protein kinases.
T11254 F-1 ROS , ALK , ROS Kinase
F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathwa...
T16153 MS4078 ALK , Ligand for E3 Ligase
MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19 nM for binding affinity to ALK.
T1962 ASP3026 ASP 3026 Apoptosis , ALK
ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies, Positive for Anaplastic Lymphoma Kinase, and Positive for Proto-Oncogene Tyrosine-Protein Kinase ROS.
T4015 HG-14-10-04 ALK
HG-14-10-04 is a potent and specific ALK inhibitor.
T39764 ALK2-IN-4 ALK2-IN-4
ALK2-IN-4, a highly effective ALK2 inhibitor.
T4257 Belizatinib TSR-011 Trk receptor , ALK
Belizatinib (TSR-011) is an effective, oral and dual inhibitor of ALK (IC50: 0.7 nM, wild-type recombinant ALK) and TRKA, TRKB, and TRKC.
T3621 Brigatinib AP-26113 EGFR , FLT , ROS , IGF-1R , ALK
Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.
T4071 Repotrectinib TPX-0005,TPX 0005,TPX0005 Trk receptor , ROS , Src , ALK , ROS Kinase
Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01 nM, 5.3 nM, 1.08 nM and 1.26 nM for WT ALK, SRC, ALK L1196M and ALK G1202R, respectively.
T1791 Ceritinib LDK378 Serine Protease , IGF-1R , ALK
Ceritinib (LDK378) is a specific ALK inhibitor (IC50: 0.2 nM).
T13416 ZX-29 ALK
ZX-29 is a potent and selective inhibitor of ALK(IC50 of 2.1 nM, 1.3 nM and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively), and also induces protective autophagy and has antitumor effect.
T1661 Crizotinib PF-02341066 c-Met/HGFR , ROS , ALK , Autophagy , ROS Kinase
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.
T3550 X-376 Ensartinib,X-396 c-Met/HGFR , ALK
X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inh...
T2655 CEP-37440 CEP37440 FAK , ALK
CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).
T2641 KRCA-0008 KRCA 0008,KRCA0008 ACK , ALK
KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.
T36620 ALK4290 ALK4290
ALK4290 (AKST4290) is a potent and orally actively CCR3 inhibitor, compound Example 2, with a Ki of 3.2 nM for hCCR3[1]. ALK4290 can be used for the research of neovascular age-related macular degeneration and Parkinsoni...
T27790 Labradimil RMP-7,ALK-01-040,Receptor-mediated permeabiliser-7,DRG0182,DRG 0182,DRG-0182
Labradimil is a bradykinin B2 receptor agonist. Labradimil increases the permeability of human brain microvascular endothelial cell monolayers. Labradimil enhances delivery of hydrophilic chemotherapeutics and increases ...

Compounds

EML4-ALK kinase inhibitor 1
T11184
Synonym: EML4 ALK kinase inhibitor 1,EML4-​ALK kinase inhibitor 1
Target: ALK
ALK inhibitor 1
T10285
Synonym:
Target: FAK, IGF-1R, ALK
ALK inhibitor 2
T3041
Synonym:
Target: FAK, ALK
ALK-IN-1
T3059
Synonym: AP26113,Brigatinib,AP26113-analog
Target: EGFR, IGF-1R, ALK
ALK kinase inhibitor-1
T6409
Synonym: SAR348830
Target: Others
ALK/ROS1 inhibitor 2e HCL
T67699L
Synonym: (R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride(2365497-12-5 Free base)
Target: Apoptosis
AZD-3463
T1967
Synonym: ALK/IGF1R inhibitor
Target: Apoptosis, IGF-1R, ALK, Autophagy
ALK-001
T29867
Synonym: C-20D3vitamin A,C-20-D3-Retinyl Acetate,ALK 001,ALK001,C-20-D3-vitamin A
Target:
ALK-IN-9
T39896
Synonym:
Target:
ALK-IN-13
T38583
Synonym:
Target:
ALK-IN-12
T38584
Synonym:
Target:
ALK-IN-5
T10283
Synonym:
Target: ALK
ALK-IN-6
T10284
Synonym:
Target: Others
ALK/ROS1-IN-1
T10286
Synonym:
Target: Others
ALK-IN-22
T63130
Synonym:
Target:
ALK-IN-21
T74522
Synonym:
Target:
ALK-IN-27
T83146
Synonym:
Target:
ALK-IN-23
T64027
Synonym:
Target:
ALK/EGFR-IN-3
T79394
Synonym:
Target:
ALK/EGFR-IN-1
T79392
Synonym:
Target: EGFR
TRK/ALK-IN-1
T72931
Synonym:
Target:
ALK/EGFR-IN-2
T79393
Synonym:
Target:
6-Alkynyl-fucose
T26394
Synonym: 6-Alk-Fuc
Target:
Biotin-PEG-Alk (MW 10000)
T82873
Synonym:
Target:
Biotin-PEG-Alk (MW 600)
T82869
Synonym:
Target:
Biotin-PEG-Alk (MW 20000)
T82871
Synonym:
Target:
Biotin-PEG-Alk (MW 1000)
T82874
Synonym:
Target:
Biotin-PEG-Alk (MW 2000)
T82872
Synonym:
Target:
Biotin-PEG-Alk (MW 3400)
T82870
Synonym:
Target:
ALK2-IN-2
T10287
Synonym:
Target: ALK, TGF-beta/Smad
Alkynyl Palmitic Acid
T14185
Synonym:
Target: Others, PROTAC Linker
JH-VIII-157-02
T15612
Synonym:
Target: Microtubule Associated, ALK
CEP-28122
T2612
Synonym:
Target: ALK
GSK1838705A
T3079
Synonym:
Target: IGF-1R, JNK, S6 Kinase, ALK
F-1
T11254
Synonym:
Target: ROS, ALK, ROS Kinase
MS4078
T16153
Synonym:
Target: ALK, Ligand for E3 Ligase
ASP3026
T1962
Synonym: ASP 3026
Target: Apoptosis, ALK
HG-14-10-04
T4015
Synonym:
Target: ALK
ALK2-IN-4
T39764
Synonym: ALK2-IN-4
Target:
Belizatinib
T4257
Synonym: TSR-011
Target: Trk receptor, ALK
Brigatinib
T3621
Synonym: AP-26113
Target: EGFR, FLT, ROS, IGF-1R, ALK
Repotrectinib
T4071
Synonym: TPX-0005,TPX 0005,TPX0005
Target: Trk receptor, ROS, Src, ALK, ROS Kinase
Ceritinib
T1791
Synonym: LDK378
Target: Serine Protease, IGF-1R, ALK
ZX-29
T13416
Synonym:
Target: ALK
Crizotinib
T1661
Synonym: PF-02341066
Target: c-Met/HGFR, ROS, ALK, Autophagy, ROS Kinase
X-376
T3550
Synonym: Ensartinib,X-396
Target: c-Met/HGFR, ALK
CEP-37440
T2655
Synonym: CEP37440
Target: FAK, ALK
KRCA-0008
T2641
Synonym: KRCA 0008,KRCA0008
Target: ACK, ALK
ALK4290
T36620
Synonym: ALK4290
Target:
Labradimil
T27790
Synonym: RMP-7,ALK-01-040,Receptor-mediated permeabiliser-7,DRG0182,DRG 0182,DRG-0182
Target:
1 2 3 4 5
Cat No. Product Name Synonyms Targets
T8152 6-Demethoxytangeretin MAPK , ALK
6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus depressa.
T4958 (-)-Alkannin Alkannin,Shikonin Apoptosis , PI3K
(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics, a...
T5703 β,β-Dimethylacrylalkannin Others
β,β-Dimethylacrylalkannin is a natural product isolated from Arnebia nobilis Reichb.f, increases collagen and involucrin content in skin cells.
TN6720 Acetylalkannin Acetyl alkannin,Alkannin acetate Antibacterial
Acetylalkannin (Alkannin acetate), an isohexenylnaphthazarin pigment extracted from Arnebia euchroma, exhibits antimicrobial and cytotoxic properties.
T35951 Alkaline Phosphatase Others
Alkaline Phosphatase is an ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values.
T60581 Alkannin
Alkannin is a potent and specific tumor-specific pyruvate kinase-M2 (PKM2) inhibitor that does not inhibit PKM1 and pyruvate kinase-L (PKL). Alkannin is a potential anticancer agent [1].

Natural Products

6-Demethoxytangeretin
T8152
Synonym:
Target: MAPK, ALK
(-)-Alkannin
T4958
Synonym: Alkannin,Shikonin
Target: Apoptosis, PI3K
β,β-Dimethylacrylalkannin
T5703
Synonym:
Target: Others
Acetylalkannin
TN6720
Synonym: Acetyl alkannin,Alkannin acetate
Target: Antibacterial
Alkaline Phosphatase
T35951
Synonym:
Target: Others
Alkannin
T60581
Synonym:
Target:

Recombinant Proteins

Species：
Human (45)
Mouse (20)
Canine (7)
Rat (5)
Cynomolgus (4)
Cynomolgus,Rhesus (2)
Rhesus (2)
Agrobacterium fabrum (1)
Caulobacter vibrioides (1)
E. coli (1)
Expression System：
HEK293 (64)
E. coli (9)
Human Cells (9)
Baculovirus-Insect Cells (7)
Baculovirus (1)
Yeast (1)
Tag：
hFc (23)
His (19)
His,hFc (7)
C-His (5)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (5)
C-6His (4)
C-hFc (4)
Tag Free (4)
C-Fc (3)
His,GST (3)
Cat No. Product Name Species Expression System
TMPY-01168 ALK-1 Protein, Human, Recombinant (His) Human HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-04774 ALK-2/ACVR1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPK-00927 ALK Protein, Mouse, Recombinant (hFc) Mouse HEK293
Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its genetic aberrations (e.g. gene rearrangements and mutations) in...
TMPY-00650 ALK-1 Protein, Human, Recombinant (hFc) Human HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-01096 ALK-2/ACVR1 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPJ-01158 ALK-2/ACVR1 Protein, Human, Recombinant (hFc) Human Human Cells
Activin RIA, also known as ALK-2, TSK-7L, SKR1, TSR-I, and ACTR-I, is a glycosylated 65 kDa type I receptor in the TGF-beta serine/threonine kinase receptor family. Binding of TGF-beta superfamily ligands induces formati...
TMPY-05771 ALK-5 Protein, Human, Recombinant (hFc) Human HEK293
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si...
TMPJ-00304 ALK-1 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angi...
TMPY-00486 ALK-7 Protein, Human, Recombinant (hFc) Human HEK293
ALK-7, also known as ALK7 and ACVR1C, belongs to the ALK family. It is a type I receptor for the TGFB family of signaling molecules. TGF-β is the prototype of a protein superfamily which, in humans, contains at least 35 ...
TMPY-01358 ALK-5 Protein, Human, Recombinant (His & hFc) Human HEK293
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si...
TMPJ-00325 BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His) Human Human Cells
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A i...
TMPY-04366 ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) Human Baculovirus-Insect Cells
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si...
TMPY-05485 BMPR1A/ALK-3 Protein, Human, Recombinant (hFc) Human HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-05483 ALK-4/ACVR1B Protein, Human, Recombinant (hFc) Human HEK293
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer...
TMPY-01293 ALK-4/ACVR1B Protein, Human, Recombinant (His) Human HEK293
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer...
TMPY-01764 BMPR1A/ALK-3 Protein, Human, Recombinant (His) Human HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-01374 BMPR1A/ALK-3 Protein, Mouse, Recombinant (His) Mouse HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-00962 BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-00658 ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc) Human HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-01059 BMPR2 Protein, Human, Recombinant (His) Human HEK293
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPK-00305 TGFBR1 Protein, Human, Recombinant (mFc & Avi) Human HEK293
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPY-03678 ALK-1 Protein, Canine, Recombinant (hFc) Canine HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-03315 ALK-1 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-02253 ENPP7 Protein, Mouse, Recombinant (His) Mouse HEK293
Ectonucleotide pyrophosphatase / phosphodiesterase family member 7, also known as Alkaline sphingomyelin phosphodiesterase, Intestinal alkaline sphingomyelinase, Alk-Smase, ENPP7 and NPP-7, is a single-pass type I memb...
TMPY-03187 ALK-7 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
ALK-7, also known as ALK7 and ACVR1C, belongs to the ALK family. It is a type I receptor for the TGFB family of signaling molecules. TGF-β is the prototype of a protein superfamily which, in humans, contains at least 35 ...
TMPY-00310 ALK-1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-03157 ALK-2/ACVR1 Protein, Rat, Recombinant (hFc) Rat HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03706 ALK-2/ACVR1 Protein, Canine, Recombinant (hFc) Canine HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03100 ALK-4/ACVR1B Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer...
TMPY-03300 ALK-4/ACVR1B Protein, Rat, Recombinant (hFc) Rat HEK293
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer...
TMPY-00662 ALK-1 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-03707 ALK-2/ACVR1 Protein, Canine, Recombinant (His) Canine HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-03247 ALK-2/ACVR1 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-00614 BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc) Canine HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-00444 ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc) Mouse HEK293
ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer...
TMPY-00757 ALK-1 Protein, Rat, Recombinant (His & hFc) Rat HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-03362 BMPRIB Protein, Human, Recombinant (hFc) Human HEK293
BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These pro...
TMPY-04367 BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST) Human Baculovirus-Insect Cells
BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These pro...
TMPH-00915 ALKAL2 Protein, Human, Recombinant (E. coli, His & Myc) Human E. coli
ALKAL2 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli.
TMPH-00914 ALKAL2 Protein, Human, Recombinant (His & Myc) Human Baculovirus
ALKAL2 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPY-01070 ENPP7 Protein, Human, Recombinant (His) Human HEK293
Ectonucleotide pyrophosphatase / phosphodiesterase family member 7, also known as Alkaline sphingomyelin phosphodiesterase, Intestinal alkaline sphingomyelinase, Alk-Smase, ENPP7 and NPP-7, is a single-pass type I memb...
TMPY-04496 BMPRIB Protein, Mouse, Recombinant (hFc) Mouse HEK293
BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These pro...
TMPJ-01178 TGFBR1 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Pho...
TMPY-00683 BMPR2 Protein, Human, Recombinant (His & hFc) Human HEK293
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPK-00306 TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated Human HEK293
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPK-00767 SLPI Protein, Human, Recombinant (hFc) Human HEK293
Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation...
TMPK-00924 SLPI Protein, Mouse, Recombinant (hFc) Mouse HEK293
Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation...
TMPY-00663 Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) Human HEK293
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal...
TMPY-02650 Alkaline phosphatase Protein, Human, Recombinant (His) Human HEK293
ALPI encodes for intestinal phosphatase alkaline, a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activit...
TMPK-00639 Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) Rat HEK293
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ...
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ALK-1 Protein, Human, Recombinant (His)
TMPY-01168
Species: Human
Expression System: HEK293
ALK-2/ACVR1 Protein, Human, Recombinant (His)
TMPY-04774
Species: Human
Expression System: Baculovirus-Insect Cells
ALK Protein, Mouse, Recombinant (hFc)
TMPK-00927
Species: Mouse
Expression System: HEK293
ALK-1 Protein, Human, Recombinant (hFc)
TMPY-00650
Species: Human
Expression System: HEK293
ALK-2/ACVR1 Protein, Mouse, Recombinant (His & hFc)
TMPY-01096
Species: Mouse
Expression System: HEK293
ALK-2/ACVR1 Protein, Human, Recombinant (hFc)
TMPJ-01158
Species: Human
Expression System: Human Cells
ALK-5 Protein, Human, Recombinant (hFc)
TMPY-05771
Species: Human
Expression System: HEK293
ALK-1 Protein, Mouse, Recombinant (hFc)
TMPJ-00304
Species: Mouse
Expression System: Human Cells
ALK-7 Protein, Human, Recombinant (hFc)
TMPY-00486
Species: Human
Expression System: HEK293
ALK-5 Protein, Human, Recombinant (His & hFc)
TMPY-01358
Species: Human
Expression System: HEK293
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
TMPJ-00325
Species: Human
Expression System: Human Cells
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST)
TMPY-04366
Species: Human
Expression System: Baculovirus-Insect Cells
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc)
TMPY-05485
Species: Human
Expression System: HEK293
ALK-4/ACVR1B Protein, Human, Recombinant (hFc)
TMPY-05483
Species: Human
Expression System: HEK293
ALK-4/ACVR1B Protein, Human, Recombinant (His)
TMPY-01293
Species: Human
Expression System: HEK293
BMPR1A/ALK-3 Protein, Human, Recombinant (His)
TMPY-01764
Species: Human
Expression System: HEK293
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His)
TMPY-01374
Species: Mouse
Expression System: HEK293
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc)
TMPY-00962
Species: Mouse
Expression System: HEK293
ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc)
TMPY-00658
Species: Human
Expression System: HEK293
BMPR2 Protein, Human, Recombinant (His)
TMPY-01059
Species: Human
Expression System: HEK293
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TMPK-00305
Species: Human
Expression System: HEK293
ALK-1 Protein, Canine, Recombinant (hFc)
TMPY-03678
Species: Canine
Expression System: HEK293
ALK-1 Protein, Cynomolgus, Recombinant (hFc)
TMPY-03315
Species: Cynomolgus
Expression System: HEK293
ENPP7 Protein, Mouse, Recombinant (His)
TMPY-02253
Species: Mouse
Expression System: HEK293
ALK-7 Protein, Rhesus, Recombinant (hFc)
TMPY-03187
Species: Rhesus
Expression System: HEK293
ALK-1 Protein, Cynomolgus, Recombinant (His)
TMPY-00310
Species: Cynomolgus
Expression System: HEK293
ALK-2/ACVR1 Protein, Rat, Recombinant (hFc)
TMPY-03157
Species: Rat
Expression System: HEK293
ALK-2/ACVR1 Protein, Canine, Recombinant (hFc)
TMPY-03706
Species: Canine
Expression System: HEK293
ALK-4/ACVR1B Protein, Rhesus, Recombinant (hFc)
TMPY-03100
Species: Rhesus
Expression System: HEK293
ALK-4/ACVR1B Protein, Rat, Recombinant (hFc)
TMPY-03300
Species: Rat
Expression System: HEK293
ALK-1 Protein, Mouse, Recombinant (His & hFc)
TMPY-00662
Species: Mouse
Expression System: HEK293
ALK-2/ACVR1 Protein, Canine, Recombinant (His)
TMPY-03707
Species: Canine
Expression System: HEK293
ALK-2/ACVR1 Protein, Cynomolgus, Recombinant (hFc)
TMPY-03247
Species: Cynomolgus
Expression System: HEK293
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
TMPY-00614
Species: Canine
Expression System: HEK293
ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc)
TMPY-00444
Species: Mouse
Expression System: HEK293
ALK-1 Protein, Rat, Recombinant (His & hFc)
TMPY-00757
Species: Rat
Expression System: HEK293
BMPRIB Protein, Human, Recombinant (hFc)
TMPY-03362
Species: Human
Expression System: HEK293
BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST)
TMPY-04367
Species: Human
Expression System: Baculovirus-Insect Cells
ALKAL2 Protein, Human, Recombinant (E. coli, His & Myc)
TMPH-00915
Species: Human
Expression System: E. coli
ALKAL2 Protein, Human, Recombinant (His & Myc)
TMPH-00914
Species: Human
Expression System: Baculovirus
ENPP7 Protein, Human, Recombinant (His)
TMPY-01070
Species: Human
Expression System: HEK293
BMPRIB Protein, Mouse, Recombinant (hFc)
TMPY-04496
Species: Mouse
Expression System: HEK293
TGFBR1 Protein, Mouse, Recombinant (hFc)
TMPJ-01178
Species: Mouse
Expression System: Human Cells
BMPR2 Protein, Human, Recombinant (His & hFc)
TMPY-00683
Species: Human
Expression System: HEK293
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TMPK-00306
Species: Human
Expression System: HEK293
SLPI Protein, Human, Recombinant (hFc)
TMPK-00767
Species: Human
Expression System: HEK293
SLPI Protein, Mouse, Recombinant (hFc)
TMPK-00924
Species: Mouse
Expression System: HEK293
Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His)
TMPY-00663
Species: Human
Expression System: HEK293
Alkaline phosphatase Protein, Human, Recombinant (His)
TMPY-02650
Species: Human
Expression System: HEK293
Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His)
TMPK-00639
Species: Rat
Expression System: HEK293
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Cat No. Product Name
L6110 Alkaloid Natural Product Library

468 compounds
A unique collection of 468 natural alkaloids can be used for high throughput and high content screening；

Libraries

Alkaloid Natural Product Library
L6110
Compounds: 468
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