Estrogen Receptor/ERR

The ERRs are orphan nuclear receptors, meaning the identity of their endogenous ligand has yet to be unambiguously determined. They are named because of sequence homology with estrogen receptors, but do not appear to bind estrogens or other tested steroid hormones.There are three human estrogen related receptors:ERRα,ERRβand ERRγ .

Cat. No.	Product name	CAS No.	Purity
T13674	Elacestrant	722533-56-4	98%
T13674	Elacestrant with IC50s of 48 and 870 nM for ERα and ERβ, respectively.Elacestrant is an orally available selective estrogen receptor degrader .
T3645	Endoxifen E-isomer hydrochloride	1197194-61-8	98%
T3645	Endoxifen, a tamoxifen metabolite, is effective specific Estrogen Response Modifier (SERM).
T11237	Camizestrant	2222844-89-3	98%
T11237	Camizestrant is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1].
T6404	Bazedoxifene hydrochloride	198480-56-7	98%
T6404	Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectivel...
T11237L	Camizestrant TFA	T11237L	98%
T11237L	Camizestrant TFA is a potent and orally active antagonist of estrogen receptor (ER).
T20419	Raloxifene	84449-90-1	98%
T20419	Raloxifene is a selective oestrogen receptor modulator. It has effects on bone and breast cancer and cardiovascular disease risk.
T6827	Endoxifen Z-isomer hydrochloride	1032008-74-4	98%
T6827	Endoxifen HCl is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.
T11098	Droloxifene	82413-20-5	98%
T11098	Droloxifene, a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells....
T10239	Acolbifene	182167-02-8	98%
T10239	Acolbifene is a selective antagonist of estrogen receptors with IC50s of 2 nM and 0.4 nM for estradiol-induced transcriptional activity of ERα and ERβ. Acolbifen...
TN1052	Lindleyin	59282-56-3	98%
TN1052	Lindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens.
T36857L	Premarin	481-97-0	98%
T36857L	Premarin is an an estrogen sulfate with neuroprotective actions during traumatic brain injury.
T21897L	MPP hydrochloride		98%
T21897L	MPP hydrochloride is a selective estrogen receptor (ERR) modulator.
T12654	(Rac)-Acolbifene	151533-34-5	98%
T12654	(Rac)-Acolbifene is a racemic form of EM652 with anti-estrogenic and estrogenic activities.
T20625	Prochloraz	67747-09-5	98%
T20625	Prochloraz, a broad-spectrum contact imidazole fungicide, is used against several diseases in wheat, barley, and oleaginous plants but also for the treatment of ...
T7389	G15	1161002-05-6
T7389	G15 is a cell-permeable non-steroidal antagonist of GPER (Ki = 20 nM)
T6533	Hexestrol	84-16-2	100%
T6533	Hexestrol binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.
T1579	Mestranol	72-33-3	100%
T1579	Mestranol, a semisynthetic estrogen, is used as an estrogen receptor agonist and must be demethylated to be biologically active.
T39710	ARV-471	2229711-68-4	97.15%
T39710	ARV-471 is a orally active Cereblon -based estrogen receptor ( ER ) PROTAC degrader. ARV-471 is developed for the research of breast cancer.
T2882	Genistin	529-59-9	97.65%
T2882	Genistin is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anti...
T15788	LSZ-102	2135600-76-7	97.84%
T15788	LSZ-102 is an effective and selective degrader of estrogen receptor (IC50 = 0.2 nM) and can be used in studies about ERα positive breast cancer.