w 7

W 7 is a biochemical.

BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.

W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride induces apoptosis and has antitumor activity.

GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.

C.I. Pigment Yellow 74 is a bioactive chemical.

BW 723C86 is a selective 5-HT2B receptor agonist with anxiolytic activity. It induces overeating and reduced grooming in rats and can be used in neurodegenerative disease research.

W 77 is a biochemical.

BW 737C89 is a highly potent dopamine D1 receptor antagonist; BW-737C is the (S)-isomer; BW-736C is the (R)-isomer.

mPEG-amine (MW 750) can synthesize folate-conjugated polymer micelles for encapsulating the anticancer agent 9-nitrocamptothecin (HY-16560). These folate-conjugated polymer micelles serve as effective carriers for poorly soluble anticancer drugs, avoiding macrophages and targeting tumor cells through folate receptor (FR)-mediated endocytosis.

m-PEG-thiol (MW 750) is utilized to modify thiolated DNA for the synthesis of gold nanorods (AuNR). Using an mPEG-SH Tween 20 assisted method (where Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface), thiolated DNA can be loaded onto the AuNR. DNA AuNR has been widely applied in nanostructure assembly, gene therapy, biosensing, and drug delivery.

Poly-L-glutamic acid sodium salt (MW 7500) is a biochemical reagent.

m-PEG-OH (MW 750) (mPEG-Hydroxy (MW 750)) is a derivative of polyethylene glycol (PEG) that can be utilized for drug delivery applications.

mPEG-CHO (MW 750) is involved in the formation of three-dimensional porous scaffolds and acts as a delivery vector when carrying active substances. The -CHO functional group interacts with the -NH2 functional group of chitosan chains to form a glutaraldehyde-like adduct, resulting in the functionalization of mPEG. This functionalization and crosslinking can affect the rigidity of the delivery system, enabling the crosslinked conjugated system to have a slow release function.

HS-PEG-COOH (Mn 7500) is a bifunctional PEG derivative utilized in the synthesis of PEG hydrogels.

Poly(ethylene glycol) dimethacrylate (MW 750) is a nonlinear analog of polyethylene glycol (PEG) and can be utilized as a cross-linking agent.

Poly(ethylene glycol) diacrylate (MW 700) (PEGDA (MW 700)) is a derivative of polyethylene glycol and is utilized in the formation of cross-linked polymers.

Dextran T70 (MW 70,000) is a complex carbohydrate polymer composed of glucose molecules linked by glycosidic bonds. It is highly soluble in water, making it suitable for use as a viscosity regulator or stabilizer in foods, paints, and adhesives. In the biomedical sector, dextran is frequently utilized as a plasma expander due to its capability to increase blood volume when administered intravenously. Additionally, it can be modified to create dextran-based drug delivery systems, such as targeted nanoparticles.

Dextran T7 (MW 7,000) is a polymer of dehydrated glucose with an average molecular weight of 7,000. It exhibits excellent biodegradability and biocompatibility, making it suitable for use in the food, pharmaceutical, cosmetic, and research industries.

Lysine-dextran, 70kDa, is a dextran glycan conjugated with lysine. It demonstrates a higher binding capacity to glutamic acid-plasminogen compared to dextran alone.

Methoxypolyethylene glycol maleimide (MW 750) is a reagent used in biochemical reactions.

TRITC-dextran MW 70000 is a fluorescent dye with a molecular weight of 70 kD and an excitation wavelength of 555 nm. It is used in drug delivery due to its stability across a wide pH range (pH 2–11) and resistance to photobleaching.

Poly-L-lysine solution (0.01%, sterile-filtered, MW 70000-150000) (PLL solution (0.01%, sterile-filtered, hydrobromide, MW 70000-150000, for cell culture)) is a biochemistry reagent for cell culture.

mPEG-Mal (MW 750) is a PEG derivative utilized for the thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery research.

Obatoclax (GX15-070), a pan-BCL-2 family proteins inhibitor and BH3 mimetic, exhibits a binding affinity (K_i) of 220 nM for BCL-2. It promotes autophagy-dependent cell death and cyclin D1 degradation via the proteasome. Additionally, Obatoclax demonstrates anti-cancer properties and broad-spectrum antiparasitic activity.