ro-3

RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor

Bufuralol (Ro 3-4787) is an orally active β-adrenergic receptor blocker with a certain degree of sympathomimetic effects and can be used to study cardiovascular diseases.

RO-3306 is a selectivity ATP-competitive CDK1 inhibitor (Ki: 20 nM). The selectivity of RO-3306 for CDK1 is >15-fold higher than a diverse panel of human kinases.

Ro-3201195 is a novel orally available p38 MAPK inhibitor with high selectivity.

1-Docosahexaenoyl-sn-glycero-3-phosphocholine, an ester product, is a phospholipid containing DHA (docosahexaenoic acid), often used in biomedical research as an important source of omega-3 fatty acids.

2-Chloro-3-quinolinecarboxylic acid ,with CAS No. 73776-25-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Chloro-3-quinolinecarboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Fluoro-3-(trifluoromethyl)benzoic acid ,with CAS No. 115029-22-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Fluoro-3-(trifluoromethyl)benzoic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2,6-Dichloro-3-pyridinamine ,with CAS No. 62476-56-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2,6-Dichloro-3-pyridinamine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Tetrahydro-3-furoic acid ,with CAS No. 89364-31-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Tetrahydro-3-furoic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4,5-Dichloro-3(2H)-pyridazinone ,with CAS No. 932-22-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4,5-Dichloro-3(2H)-pyridazinone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-Chloro-3-pyridinol ,with CAS No. 74115-12-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-Chloro-3-pyridinol provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Fluoro-3-methylphenol ,with CAS No. 452-70-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Fluoro-3-methylphenol provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Fluoro-3-methylpyridine ,with CAS No. 2369-18-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Fluoro-3-methylpyridine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Fluoro-3-hydroxy (1H)indazole, with CAS No. 683748-50-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Fluoro-3-hydroxy (1H)indazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Chloro-3-sulfamoylbenzoic acid ,with CAS No. 1205-30-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Chloro-3-sulfamoylbenzoic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride ,with CAS No. 84163-13-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1,2-Dihydro-3H-1,2,4-triazol-3-one ,with CAS No. 930-33-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1,2-Dihydro-3H-1,2,4-triazol-3-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Nitro-3-cresol exhibits ciliate toxicity against Tetrahymena pyriformis and is widely used in biochemical experiments and drug synthesis research.

sn-Glycero-3-phosphocholine (Choline glycerophosphate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a potential for the treatment of Alzheimer's disease and dementia. sn-Glycero-3-phosphocholine rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter. It is a non-prescription drug in most countries due to its Generally Recognised As Safe (GRAS) status [1]. Studies have investigated its efficacy for cognitive disorders including stroke and Alzheimer's disease. An Italian multicentre clinical trial on 2, 044 patients suffering from recent stroke were supplied Glycerylphosphorylcholine in doses of 1, 000 mg/day for 28 days and 400 mg three times per day for the five ensuing months. The trial confirmed the therapeutic role of alpha-GPC on the cognitive recovery of patients based on four measurement scales, three of which reached statistical significance [2].

1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (1,2-DSPE) is a phosphatidylethanolamine (PE or GPEtn). The stearic acid moieties are derived from animal fats, cocoa butter, and sesame oil. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling.

1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1H)-pyridinone has broad-spectrum antifungal activity with inhibitory effects on Candida albicans, Aspergillus niger, Pseudomonas aeruginosa and Staphylococcus aureus.

4-Chloro-3-(trifluoromethyl)phenyl isocyanate is a biochemical reagent that can be produced by a series of reactions between o-chlorobenzotrifluoride and acetic anhydride.

1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid containing the unsaturated long-chain (18:1) oleic acid inserted at the sn-1 and sn-2 positions.

4-Chloro-3-nitrobenzoic acid is a nitric oxide scavenger and has been used to study the effects of nitric oxide on the cardiovascular system and the effects of nitric oxide on the immune system.