ro 3

Ro 3-5940 HCl is a psychoactive agent, increasing in production of serotonin in central nervous system tissue.

Ro 3-7410 is an active hydroxy metabolite of bufuralol.

RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2 3 receptor

Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor for PKC-α βI βII γ ε (IC50: 5 24 14 27 24 nM), and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.

Ro 31-8220 is a potent inhibitor of PKC with IC50 values of 5, 24, 14, 27, 24, and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε, and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1, and GSK3β with IC50 values of 3, 8, 15, and 38 nM, respectively, without affecting MKK3, MKK4, MKK6, and MKK7.

Ro 31-9790, a synthetic inhibitor of metalloproteinase (MMP), is designed to target and inhibit the action of MMP enzymes.

RO 363 is an effective inotropic stimulant and is a cardiovascular modulator that decreases diastolic blood pressure and pronounces increases in myocardial contractility. Ro 363 is an effective and highly selective β1-adrenoceptor agonist.

Ro 32-0432 hydrochloride is a protein kinase C inhibitor.

Ro 32-7315 is a selective inhibitor of ADAM17.

Ro 31-1118 is a partial agonist of beta-adrenoceptor.

Ro 31-2201 is a potent inhibitor of angiotensin converting enzyme.

Ro 31-4639 is a phospholipase A2 inhibitor in vitro.

Ro 31-7837 is an opener of potassium channel.

Ro 31-8472 is an angiotensin-converting enzyme (ACE) inhibitor and an analog of cilazaprilat.

Talviraline is a RNA-directed DNA polymerase inhibitor. HBY 097 is a highly potent inhibitor of HIV-1 replication and HIV-1 induced cell killing in a variety of human cell lines as well as in fresh human peripheral blood lymphocytes and macrophages.

Ro 31-8830, a derivative of Ro 31-8425, has in vivo anti-inflammatory activity.

Ro 31-0052 is a bioactive chemical.

Ro 31-0313 is a metabolite of Ro 03-8799, radiation sensitizing agent.

Ro 31-8875 is a biochemical.

Mycro 3 is potent and selective for c-Myc in whole cell assays.

Ro 363 hydrochloride is an effective, highly selective agonist of β 1-adrenoceptor. Ro 363 hydrochloride is an effective inotropic stimulant. Ro 363 hydrochloride is a cardiovascular regulator, which can reduce diastolic blood pressure and significantly increase myocardial contractility.

(S)-Ro 32-0432 is a potent, selective inhibitor of protein kinase C (PKC) and G protein-coupled receptor kinase 5 (GRK5), demonstrating ATP-competitive and oral activity. It presents IC50 values of 9.3 nM for PKCα, 28 nM for PKCβI, 30 nM for PKCβII, 36.5 nM for PKCγ, and 108.3 nM for PKCε, showcasing its effectiveness against multiple PKC isoforms. Additionally, (S)-Ro 32-0432 inhibits T-cell activation, indicating its potential application in the research of chronic inflammatory and autoimmune diseases [1] [2].

R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1 2 4 with Ki of 2 nM 3 nM 1 nM. It is less potent to CDK7 and GSK3α β, while inactive to other kinases. Phase 1.

Zalcitabine (Dideoxycytidine)(Dideoxycytidine;ddC; 2', 3'-Dideoxycytidine) is a nucleoside analog reverse transcriptase inhibitor (NRTI); At low concentrations, It can potently inhibit HIV replication by binding to reverse transcriptase terminated synthesis of viral DNA chain.