nucleic acid

Locked nucleic acid 1 is an LNA-type nucleoside derivative.

Deoxyribonucleic Acid Sodium (Salmon testes) is a natural DNA used in studies of DNA binding agents that modulate DNA structure and function.

Ribonucleic Acid, Transfer from Brewing yeast (RNA) is a vital biomacromolecule, a polymer composed of covalently linked ribonucleotides, playing a pivotal role in processes such as protein synthesis and gene regulation.

Deoxyribonucleic acid (DNA) is a polymer formed by two polynucleotide chains winding into a double helix structure, with a backbone composed of alternating deoxyribose and phosphate groups. Deoxyribonucleic acid constitutes the fundamental component of chromosomes, serving as the molecular carrier of genetic information governing organismal development and function.

Deoxyribonucleic acid sodium salt from salmon testes (ssstDNA) is utilized in creating anti-adhesion layers (AAL) for the passivation of gold plasma sensor surfaces.

Deoxyribonucleic acid, single stranded from salmon testes, is a sodium salt form of DNA derived from salmon testes. It is utilized in basal media to support the anaerobic growth of various Bacillus mojavensis strains. Additionally, it serves as a substrate for the development of DNA detection assays.

Ribonucleic acid (yeast) is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

DMG-PEG2000 (DMG-PEG2000) can be used for the preparation of lipid nanoparticles for oral delivery of plasmid DNA in vivo to improve the mucus permeability and delivery efficiency of nanoparticles. DMG-PEG 2000 can be used for the preparation of siRNA transfected liposomes, which can improve the transfection efficiency.

Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) is a high-quality double-stranded template DNA extracted from the bovine thymus gland, widely used in studying DNA binding anticancer agents and DNA binding agents that regulate DNA structure and function.

Epimedokoreanin B (EKB), an isoprenylated flavonoid isolated from Korean Epimedium, exhibited anticancer activity in human non-small cell lung cancer (NSCLC) A549 and NCI-H292 cells.Epimedokoreanin B also possesses anti-inflammatory and antibacterial activities, and may have scavenging activity against DPPH radicals, inhibiting the proliferation of MCF-7 and HepG2 in a dose-dependent manner. Epimedokoreanin B also exhibits anti-inflammatory and antibacterial activity, with DPPH radical scavenging activity, and inhibits the proliferation of MCF-7 and HepG2 in a dose-dependent manner.Epimedokoreanin B significantly inhibits the formation of N (α)-(carboxymethyl)lysine (CML) and N (Ï)-(carboxymethyl)arginine (CMA), and prevents clinical complications of diabetes mellitus through the inhibition of advanced glycation end-products (AGEs).

Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation. Fludarabine has antitumor activity and can be used for the treatment of leukemia and lymphoma.

Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM. It plays a central role in purine catabolism through the degradation of bioactive nucleotides facilitated by nucleic acid and nucleotide intermediates.

Pyrazoloacridine (PD 115934) is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 μM in K562 cells. Pyrazoloacridine shows anti-cancer activity.

DC 07090 is a human enterovirus 71 3C protease inhibitor with antiviral activity for the study of nucleic acid virus infections.

6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.

Hypoxanthine (Purin-6-ol), also known as purine-6-ol or Hyp. Hypoxanthine is a naturally occurring purine derivative and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the nucleotide salvage pathway. Under normal circumstances hypoxanthine is readily converted to uric acid.hypoxanthine is first oxidized to xanthine, which is further oxidized to uric acid by xanthine oxidase.

Phenanthridine is a nitrogen-containing heterocyclic compound. Phenanthridine serves as the structural backbone of fluorescent dyes that bind to DNA, enabling visualization of nucleic acid positions post-electrophoresis, as seen with dyes like ethidium bromide and propidium iodide. Acridine is an isomer of Phenanthridine. Used in ecotoxicological studies. Employed in rotational spectroscopy and radio astronomy research. Functions as a dye in biological and chemical sensors.

Maleic hydrazide is a plant growth regulator and germination inhibitor that participates in nucleic acid metabolism pathways within plants, thereby inhibiting cell division in the apical meristem.

6-Mercaptopurine hydrate (6-Mercaptopurine monohydrate) is a Nucleoside Metabolic Inhibitor. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.

2'-Deoxyguanosine 5'-monophosphate disodium (5'-dGMP disodium) is a GTP derivative that serves as an oxidizable target and is used in forming polycomplexes with other compounds.

Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) are a mixture of phosphatidylethanolamines isolated from eggs, with various fatty acyl groups at the sn-1 and sn-2 positions. Glycerophospholipids and cephalins can be completely hydrolyzed to obtain 1 mol of glycerol, phosphoric acid, ethanolamine and 2 mol of fatty acids. Phosphatidylethanolamines play a role in membrane fusion and disassembly of contractile rings during cell division, regulating membrane curvature. Phosphatidylethanolamines are able to transmit infectious prions without the help of any proteins or nucleic acids. One of the main roles of Phosphatidylethanolamines in bacterial membranes is to disperse the negative charges caused by anionic membrane phospholipids.

2′-Deoxyadenosine 5′-monophosphate disodium (a nucleic acid AMP derivative) is a deoxyribonucleotide in DNA, used for studying adenosine-based interactions in DNA synthesis and damage analysis.

Pemetrexed disodium heptahydrate (LY231514) is an antifolate that inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinyl-adenosine 5'-monophosphate (GARMT) with K_i values of 1.3 nM, 7.2 nM, and 65 nM respectively. This inhibits the formation of precursor purine and pyrimidine nucleotides and cancer cell proliferation, making it suitable for research into pleural mesothelioma and non-small cell lung cancer (NSCLC).

5-Bromocytidine is a nucleoside analog that is a priority disinfection byproduct of drinking water and may interfere with nucleic acid synthesis.