nucleic acid

DMG-PEG2000 (DMG-PEG2000) can be used for the preparation of lipid nanoparticles for oral delivery of plasmid DNA in vivo to improve the mucus permeability and delivery efficiency of nanoparticles. DMG-PEG 2000 can be used for the preparation of siRNA transfected liposomes, which can improve the transfection efficiency.

Ribonucleic Acid, Transfer from Brewing yeast (RNA) is a vital biomacromolecule, a polymer composed of covalently linked ribonucleotides, playing a pivotal role in processes such as protein synthesis and gene regulation.

Deoxyribonucleic acid is a polymer composed of two polynucleotide chains that intertwine to form a double helix structure. Deoxyribonucleic acid is present in all dividing cells and is an essential component of chromosomes.

Deoxyribonucleic acid sodium salt from salmon testes (ssstDNA) is utilized in creating anti-adhesion layers (AAL) for the passivation of gold plasma sensor surfaces.

Ribonucleic acid (yeast) is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Phenanthridine is a nitrogen-containing heterocyclic compound. Phenanthridine serves as the structural backbone of fluorescent dyes that bind to DNA, enabling visualization of nucleic acid positions post-electrophoresis, as seen with dyes like ethidium bromide and propidium iodide. Acridine is an isomer of Phenanthridine. Used in ecotoxicological studies. Employed in rotational spectroscopy and radio astronomy research. Functions as a dye in biological and chemical sensors.

DLIN-MC2-DMA (DLin-M-C2-DMA) is a lipid membrane and a potential nucleic acid carrier.

DOTAP chloride (1, 2-dioleoyl-3-trimethylammonium-propane chloride) is an efficient cationic lipid, and its target is mainly the negatively charged components on the cell membrane. DOTAP chloride binds to negatively charged nucleic acids (such as DNA and RNA) by electrostatic interaction to form complexes, thereby achieving the delivery of nucleic acids.

DLinDMA, as a benchmark, is a key stable nucleic acid lipid particleslipid component.

Lipid A-11 is a lipid component of endotoxin that is primarily responsible for the toxic properties of gram-negative bacteria. Lipid A-11 constitutes the innermost region of the lipopolysaccharide (LPS) molecule, also known as endotoxin, and its hydrophobic nature facilitates anchoring of the LPS structure into the bacterial outer membrane. Lipid A-11 plays a critical role in host-pathogen interactions, contributing to septic shock and immunological activation during bacterial infections.

2-Thiouridine (s2U) is a modified nucleobase found in tRNAs that is known to stabilize U:A pairs and modestly destabilize U:G wobble pairs. Modified nucleobases, including 2-thiouridine, are used to study nucleic acid structure and function as well as to engineer novel RNA-based biomolecules.

5-Propargylamino-dCTP, also known as dCTP-PA, is a nucleoside molecule. It can form conjugates with molecular markers, enabling its application in nucleic acid labeling and sequence analysis.

L319 (Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate) is a lipid membrane, a potential nucleic acid carrier.

Dlin-MeOH is a lipid membrane and a potential nucleic acid carrier for the synthesis of DLin-MC3-DMA.

BGTC, a non-amino acid cationic lipid, serves as a vehicle for nucleic acid delivery [1].

Fluorescent DOTAP, a cationic lipid, aids research in the delivery of nucleic acids and proteins [1].

DLin-K-C3-DMA is a cationic lipid that binds to negatively charged mRNA and siRNA, commonly used in the synthesis of lipid nanoparticles (LNP) for nucleic acid delivery.

3'Ome-m7GpppAmpG ammonium, a trinucleotide Cap analogue with a locked nucleic acid (LNA) component, demonstrates substantial translational efficiency. It emerges as a promising tool in molecular biology, applicable in mRNA vaccines and transfection processes including protein production, gene therapy, and anti-cancer immunization [1].

Lipid C24, a cationic ionizable compound, plays a crucial role in creating lipid nanoparticles (LNPs) and is utilized in nucleic acid delivery research [1].

DLIN-MC4-DMA is a lipid membrane and is a potential nucleic acid carrier.

GL67 (N4-Spermine cholesteryl carbamate), a cationic lipid, facilitates the delivery of nucleic acid agents and vaccines, and is effective in gene transfection [1].

6-((4-Hydroxybutyl)amino)hexyl 2-hexyldecanoate is a lipid compound utilized in the synthesis of nanomaterials. Additionally, 6-((4-Hydroxybutyl)amino)hexyl is pivotal in creating nucleic acid delivery systems and forms a crucial component of nanolipid particles used for delivery vectors.

GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. It is utilized for the delivery of nucleic acid active molecules, vaccines, and for gene transfection.

DSPE-PEG-NHS (MW 2000), is a PEGylated phospholipid derivative containing a reactive N-hydroxysuccinimide (NHS) ester functional group. DSPE-PEG-NHS (MW 2000), is utilized in the fabrication of liposomes and lipid nanoparticles for the encapsulation and delivery of DNA and mRNA vaccines, improving stability, circulation time, and targeting capability of nucleic acid-based therapeutics.