mt-2

TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.

LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2.

Dmt-2'fluoro-da(bz) amidite is a 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotide with high affinity and specificity for RNA targets and serves as an intermediate in the synthesis of 5'-DMT-3'-phosphoramidite, an antisense compound resistant to nuclease.

DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.

Mt KARI-IN-2 (compound 5b) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 2.02 μM. It also inhibits Mtb H37Rv with a MIC value of 0.78 μM and demonstrates low cytotoxicity, as indicated by a HEK IC50 greater than 86 μg/mL [1].

2-MT 63 is a novel TIE-2 kinase inhibitor that demonstrates unique and improved kinase selectivity compared to other inhibitors known to interact with TIE-2. 2-MT 63 has a good kinase selectivity profile in enzyme assays with >30-fold selectivity (typically much greater) against the tested kinases. Importantly, the profile includes selectivity against other targets of relevance for angiogenesis (KDR, PDGFR, EPHB4).

SAMT-247 is an HIV inhibitor that acts by modifying the nucleocapsid NCp7 region of Gag in infected cells and blocking Gag processing and reducing infectivity.

5'-O-DMT-2'-O-TBDMS-Ac-rC is a modified nucleoside used in the synthesis of DNA or RNA.

5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine, an adenosine derivative, functions as an intermediate in oligonucleotide synthesis.

5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside used in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.

DMT-2'-Fluoro-DG(IB) Amidite, also known as 2'-F-ibu-dG Phosphoramidite, is a nucleoside used in the synthesis of 4'-modified 2'-deoxy-2'-fluorouridine.

2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue derived from 5'-O-DMTr-5-FUDR, exhibits strong anti-yellow fever (YFV) activity.

2'-F-Ac-dC Phosphoramidite (Dmt-2'-F-dC Ac Amidite) is a compound used in the synthesis of cyclic purine dinucleotides.

BMT-297376, the optimized Linrodostat, is a potent inhibitor of IDO1 (Indoleamine 2,3-dioxygenase 1).

5'-O-DMT-2'-O-TBDMS-Bz-rC, a modified nucleoside, is used in DNA or RNA synthesis.

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine can be used for the silyl protection of ribonucleosides.

DMT-2'-F-Bz-dA is a useful organic compound for research related to life sciences. The catalog number is T66056 and the CAS number is 136834-21-4.

DMT-2'O-Methyl-rU Phosphoramidite (catalog number T66403, CAS number 110764-79-9) is a valuable organic compound used in life sciences research.

N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor activity, especially against indolent lymphoid malignancies, through mechanisms such as inhibiting DNA synthesis and inducing apoptosis, among others [1].

3-Cyanovinyl-9-(5'-O-DMT-2'-deoxyribofuranosyl)carbazole, a purine nucleoside analog, demonstrates extensive antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms encompass DNA synthesis inhibition and apoptosis induction, among others [1].

N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog that inhibits DNA methyltransferases (such as Zebularine).

DMT-2'-OMe-Bz-C is a 2'-O-Methyl nucleoside.

N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is a 2'-modified nucleoside derivative; a protected nucleoside with (NH2/OH) groups.

5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is a valuable organic compound for life sciences research (catalog number: TNU0961, CAS number: 875302-45-7).